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Left Ventricular Hypertrophy with Strain

MedGen UID:
1695111
•Concept ID:
C5202584
•
Disease or Syndrome

Definition

A finding of left ventricular hypertrophy based on the analysis of diagnostic metrics that may indicate a higher risk for cardiovascular events. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLeft Ventricular Hypertrophy with Strain

Professional guidelines

PubMed

Efficacy of echocardiography for differential diagnosis of left ventricular hypertrophy: special focus on speckle-tracking longitudinal strain.
Tanaka H
J Echocardiogr 2021 Jun;19(2):71-79. Epub 2021 Jan 18 doi: 10.1007/s12574-020-00508-3. PMID: 33460030Free PMC Article
Challenges in the diagnosis and management of acromegaly: a focus on comorbidities.
Abreu A, Tovar AP, Castellanos R, Valenzuela A, Giraldo CM, Pinedo AC, Guerrero DP, Barrera CA, Franco HI, Ribeiro-Oliveira A Jr, Vilar L, Jallad RS, Duarte FG, Gadelha M, Boguszewski CL, Abucham J, Naves LA, Musolino NR, de Faria ME, Rossato C, Bronstein MD
Pituitary 2016 Aug;19(4):448-57. doi: 10.1007/s11102-016-0725-2. PMID: 27279011Free PMC Article
Differential diagnosis between left ventricular hypertrophy and cardiomyopathy in childhood.
Östman-Smith I
J Electrocardiol 2014 Sep-Oct;47(5):661-8. Epub 2014 Jul 3 doi: 10.1016/j.jelectrocard.2014.07.002. PMID: 25060129

Recent clinical studies

Etiology

Nonspecific electrocardiographic abnormalities are associated with increased length of stay and adverse cardiac outcomes in prehospital chest pain.
Rivero D, Alhamaydeh M, Faramand Z, Alrawashdeh M, Martin-Gill C, Callaway C, Drew B, Al-Zaiti S
Heart Lung 2019 Mar-Apr;48(2):121-125. Epub 2018 Oct 8 doi: 10.1016/j.hrtlng.2018.09.001. PMID: 30309629Free PMC Article
Electrocardiographic abnormalities and mortality in aging survivors of childhood cancer: A report from the St Jude Lifetime Cohort Study.
Mulrooney DA, Soliman EZ, Ehrhardt MJ, Lu L, Duprez DA, Luepker RV, Armstrong GT, Joshi VM, Green DM, Srivastava D, Krasin MJ, Morris GS, Robison LL, Hudson MM, Ness KK
Am Heart J 2017 Jul;189:19-27. Epub 2017 Apr 4 doi: 10.1016/j.ahj.2017.03.023. PMID: 28625376Free PMC Article
Electrocardiographic left ventricular hypertrophy with strain pattern: prevalence, mechanisms and prognostic implications.
Ogah OS, Oladapo OO, Adebiyi AA, Adebayo AK, Aje A, Ojji DB, Salako BL, Falase AO
Cardiovasc J Afr 2008 Jan-Feb;19(1):39-45. PMID: 18320088Free PMC Article
Association between electrocardiographic left ventricular hypertrophy with strain pattern and left ventricular structure and function.
Ogah OS, Adebiyi AA, Oladapo OO, Aje A, Ojji DB, Adebayo AK, Salako BL, Falase AO
Cardiology 2006;106(1):14-21. Epub 2006 Apr 4 doi: 10.1159/000092478. PMID: 16601328
Discrete subaortic stenosis.
Khan MM, Varma MP, Cleland J, O'Kane HO, Webb SW, Mulholland HC, Adgey AA
Br Heart J 1981 Oct;46(4):421-31. doi: 10.1136/hrt.46.4.421. PMID: 6457617Free PMC Article

Diagnosis

Nonspecific electrocardiographic abnormalities are associated with increased length of stay and adverse cardiac outcomes in prehospital chest pain.
Rivero D, Alhamaydeh M, Faramand Z, Alrawashdeh M, Martin-Gill C, Callaway C, Drew B, Al-Zaiti S
Heart Lung 2019 Mar-Apr;48(2):121-125. Epub 2018 Oct 8 doi: 10.1016/j.hrtlng.2018.09.001. PMID: 30309629Free PMC Article
Electrocardiographic abnormalities and mortality in aging survivors of childhood cancer: A report from the St Jude Lifetime Cohort Study.
Mulrooney DA, Soliman EZ, Ehrhardt MJ, Lu L, Duprez DA, Luepker RV, Armstrong GT, Joshi VM, Green DM, Srivastava D, Krasin MJ, Morris GS, Robison LL, Hudson MM, Ness KK
Am Heart J 2017 Jul;189:19-27. Epub 2017 Apr 4 doi: 10.1016/j.ahj.2017.03.023. PMID: 28625376Free PMC Article
Left ventricular hypertrophy with strain and aortic stenosis.
Shah AS, Chin CW, Vassiliou V, Cowell SJ, Doris M, Kwok TC, Semple S, Zamvar V, White AC, McKillop G, Boon NA, Prasad SK, Mills NL, Newby DE, Dweck MR
Circulation 2014 Oct 28;130(18):1607-16. Epub 2014 Aug 28 doi: 10.1161/CIRCULATIONAHA.114.011085. PMID: 25170097
Electrocardiographic left ventricular hypertrophy with strain pattern: prevalence, mechanisms and prognostic implications.
Ogah OS, Oladapo OO, Adebiyi AA, Adebayo AK, Aje A, Ojji DB, Salako BL, Falase AO
Cardiovasc J Afr 2008 Jan-Feb;19(1):39-45. PMID: 18320088Free PMC Article
Initial ECG in Q wave and non-Q wave myocardial infarction.
Fesmire FM, Percy RF, Wears RL, MacMath TL
Ann Emerg Med 1989 Jul;18(7):741-6. doi: 10.1016/s0196-0644(89)80007-1. PMID: 2735591

Therapy

Electrocardiographic abnormalities and mortality in aging survivors of childhood cancer: A report from the St Jude Lifetime Cohort Study.
Mulrooney DA, Soliman EZ, Ehrhardt MJ, Lu L, Duprez DA, Luepker RV, Armstrong GT, Joshi VM, Green DM, Srivastava D, Krasin MJ, Morris GS, Robison LL, Hudson MM, Ness KK
Am Heart J 2017 Jul;189:19-27. Epub 2017 Apr 4 doi: 10.1016/j.ahj.2017.03.023. PMID: 28625376Free PMC Article
Left ventricular hypertrophy with strain and aortic stenosis.
Shah AS, Chin CW, Vassiliou V, Cowell SJ, Doris M, Kwok TC, Semple S, Zamvar V, White AC, McKillop G, Boon NA, Prasad SK, Mills NL, Newby DE, Dweck MR
Circulation 2014 Oct 28;130(18):1607-16. Epub 2014 Aug 28 doi: 10.1161/CIRCULATIONAHA.114.011085. PMID: 25170097
Electrocardiographic left ventricular hypertrophy with strain pattern: prevalence, mechanisms and prognostic implications.
Ogah OS, Oladapo OO, Adebiyi AA, Adebayo AK, Aje A, Ojji DB, Salako BL, Falase AO
Cardiovasc J Afr 2008 Jan-Feb;19(1):39-45. PMID: 18320088Free PMC Article
The influence of pre-operative electrocardiographic abnormalities and cardiovascular risk factors on patient and graft survival following renal transplantation.
Woo YM, McLean D, Kavanagh D, Ward L, Aitken S, Miller GJ, Egan P, Hughes K, Clark L, Carswell K, Morris ST, Northridge DB, Rodger RS, Jardine AG
J Nephrol 2002 Jul-Aug;15(4):380-6. PMID: 12243367
The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial of cardiovascular events in hypertension. Rationale and design.
Mann J, Julius S
Blood Press 1998 May;7(3):176-83. doi: 10.1080/080370598437394. PMID: 9758088

Prognosis

Nonspecific electrocardiographic abnormalities are associated with increased length of stay and adverse cardiac outcomes in prehospital chest pain.
Rivero D, Alhamaydeh M, Faramand Z, Alrawashdeh M, Martin-Gill C, Callaway C, Drew B, Al-Zaiti S
Heart Lung 2019 Mar-Apr;48(2):121-125. Epub 2018 Oct 8 doi: 10.1016/j.hrtlng.2018.09.001. PMID: 30309629Free PMC Article
Left ventricular hypertrophy with strain and aortic stenosis.
Shah AS, Chin CW, Vassiliou V, Cowell SJ, Doris M, Kwok TC, Semple S, Zamvar V, White AC, McKillop G, Boon NA, Prasad SK, Mills NL, Newby DE, Dweck MR
Circulation 2014 Oct 28;130(18):1607-16. Epub 2014 Aug 28 doi: 10.1161/CIRCULATIONAHA.114.011085. PMID: 25170097
Electrocardiographic left ventricular hypertrophy with strain pattern: prevalence, mechanisms and prognostic implications.
Ogah OS, Oladapo OO, Adebiyi AA, Adebayo AK, Aje A, Ojji DB, Salako BL, Falase AO
Cardiovasc J Afr 2008 Jan-Feb;19(1):39-45. PMID: 18320088Free PMC Article
Association between electrocardiographic left ventricular hypertrophy with strain pattern and left ventricular structure and function.
Ogah OS, Adebiyi AA, Oladapo OO, Aje A, Ojji DB, Adebayo AK, Salako BL, Falase AO
Cardiology 2006;106(1):14-21. Epub 2006 Apr 4 doi: 10.1159/000092478. PMID: 16601328
Discrete subaortic stenosis.
Khan MM, Varma MP, Cleland J, O'Kane HO, Webb SW, Mulholland HC, Adgey AA
Br Heart J 1981 Oct;46(4):421-31. doi: 10.1136/hrt.46.4.421. PMID: 6457617Free PMC Article

Clinical prediction guides

Nonspecific electrocardiographic abnormalities are associated with increased length of stay and adverse cardiac outcomes in prehospital chest pain.
Rivero D, Alhamaydeh M, Faramand Z, Alrawashdeh M, Martin-Gill C, Callaway C, Drew B, Al-Zaiti S
Heart Lung 2019 Mar-Apr;48(2):121-125. Epub 2018 Oct 8 doi: 10.1016/j.hrtlng.2018.09.001. PMID: 30309629Free PMC Article
Electrocardiographic abnormalities and mortality in aging survivors of childhood cancer: A report from the St Jude Lifetime Cohort Study.
Mulrooney DA, Soliman EZ, Ehrhardt MJ, Lu L, Duprez DA, Luepker RV, Armstrong GT, Joshi VM, Green DM, Srivastava D, Krasin MJ, Morris GS, Robison LL, Hudson MM, Ness KK
Am Heart J 2017 Jul;189:19-27. Epub 2017 Apr 4 doi: 10.1016/j.ahj.2017.03.023. PMID: 28625376Free PMC Article
Left ventricular hypertrophy with strain and aortic stenosis.
Shah AS, Chin CW, Vassiliou V, Cowell SJ, Doris M, Kwok TC, Semple S, Zamvar V, White AC, McKillop G, Boon NA, Prasad SK, Mills NL, Newby DE, Dweck MR
Circulation 2014 Oct 28;130(18):1607-16. Epub 2014 Aug 28 doi: 10.1161/CIRCULATIONAHA.114.011085. PMID: 25170097
Electrocardiographic left ventricular hypertrophy with strain pattern: prevalence, mechanisms and prognostic implications.
Ogah OS, Oladapo OO, Adebiyi AA, Adebayo AK, Aje A, Ojji DB, Salako BL, Falase AO
Cardiovasc J Afr 2008 Jan-Feb;19(1):39-45. PMID: 18320088Free PMC Article
Discrete subaortic stenosis.
Khan MM, Varma MP, Cleland J, O'Kane HO, Webb SW, Mulholland HC, Adgey AA
Br Heart J 1981 Oct;46(4):421-31. doi: 10.1136/hrt.46.4.421. PMID: 6457617Free PMC Article

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