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Increased circulating specific IgE antibody

MedGen UID:
1702753
•Concept ID:
C5139278
•
Finding
HPO: HP:0032336

Professional guidelines

PubMed

The Interaction of Innate and Adaptive Immunity and Stabilization of Mast Cell Activation in Management of Infusion Related Reactions in Patients with Fabry Disease.
Limgala RP, Fikry J, Veligatla V, Goker-Alpan O
Int J Mol Sci 2020 Sep 29;21(19) doi: 10.3390/ijms21197213. PMID: 33003611Free PMC Article
Activated circulating T follicular helper cells and skewing of T follicular helper 2 cells are down-regulated by treatment including an inhaled corticosteroid in patients with allergic asthma.
Miyajima S, Shigehara K, Kamekura R, Takaki H, Yabe H, Ikegami I, Asai Y, Nishikiori H, Chiba H, Uno E, Takahashi H, Ichimiya S
Allergol Int 2020 Jan;69(1):66-77. Epub 2019 Oct 22 doi: 10.1016/j.alit.2019.08.008. PMID: 31648923
Anti-IgE treatment in allergic rhinitis.
Bayar Muluk N, Bafaqeeh SA, Cingi C
Int J Pediatr Otorhinolaryngol 2019 Dec;127:109674. Epub 2019 Sep 10 doi: 10.1016/j.ijporl.2019.109674. PMID: 31526939

Recent clinical studies

Etiology

Anti-IgE Significantly Changes Circulating Interleukin-25, Vitamin-D and Interleukin-33 Levels in Patients with Allergic Asthma.
Yalcin AD, Uzun R
Curr Pharm Des 2019;25(35):3784-3795. doi: 10.2174/1381612825666190930095725. PMID: 31566129
Role of allergen-specific T-follicular helper cells in immunotherapy.
Yao Y, Wang ZC, Yu D, Liu Z
Curr Opin Allergy Clin Immunol 2018 Dec;18(6):495-501. doi: 10.1097/ACI.0000000000000480. PMID: 30124489
Risk and safety of immunotherapy.
Rogala B
Allergy 1998 May;53(5):473-6. doi: 10.1111/j.1398-9995.1998.tb04083.x. PMID: 9636805
Atopic dermatitis: recent therapeutic advances.
de Prost Y
Pediatr Dermatol 1992 Dec;9(4):386-9. doi: 10.1111/j.1525-1470.1992.tb00639.x. PMID: 1492066
IgG-containing and IgE-containing circulating immune complexes in patients with asthma and rhinitis.
Stevens WJ, Bridts CH
J Allergy Clin Immunol 1984 Feb;73(2):276-82. doi: 10.1016/s0091-6749(84)80020-2. PMID: 6699311

Diagnosis

Immunotherapy-induced neutralizing antibodies disrupt allergen binding and sustain allergen tolerance in peanut allergy.
LaHood NA, Min J, Keswani T, Richardson CM, Amoako K, Zhou J, Marini-Rapoport O, Bernard H, Hazebrouck S, Shreffler WG, Love JC, Pomes A, Pedersen LC, Mueller GA, Patil SU
J Clin Invest 2023 Jan 17;133(2) doi: 10.1172/JCI164501. PMID: 36647835Free PMC Article
Alcohol consumption alters anti-Strongyloides stercoralis antibodies production.
De Souza JN, Cruz ADV, Araújo WAC, Sampaio LM, Allegretti SM, Teixeira MCA, Handali S, Galvão-Castro B, Soares NM
Immunobiology 2020 Mar;225(2):151898. Epub 2019 Dec 12 doi: 10.1016/j.imbio.2019.151898. PMID: 31902530
Impaired memory B-cell development and antibody maturation with a skewing toward IgE in patients with STAT3 hyper-IgE syndrome.
van de Veen W, Krätz CE, McKenzie CI, Aui PM, Neumann J, van Noesel CJM, Wirz OF, Hagl B, Kröner C, Spielberger BD, Akdis CA, van Zelm MC, Akdis M, Renner ED
Allergy 2019 Dec;74(12):2394-2405. Epub 2019 Aug 16 doi: 10.1111/all.13969. PMID: 31269238
Local IgE in non-allergic rhinitis.
Campo P, Rondón C, Gould HJ, Barrionuevo E, Gevaert P, Blanca M
Clin Exp Allergy 2015 May;45(5):872-881. doi: 10.1111/cea.12476. PMID: 25495772
Chapter 21: Urticaria and angioedema.
Carr TF, Saltoun CA
Allergy Asthma Proc 2012 May-Jun;33 Suppl 1:70-72. doi: 10.2500/aap.2012.33.3554. PMID: 22794694

Therapy

Anti-IgE treatment in allergic rhinitis.
Bayar Muluk N, Bafaqeeh SA, Cingi C
Int J Pediatr Otorhinolaryngol 2019 Dec;127:109674. Epub 2019 Sep 10 doi: 10.1016/j.ijporl.2019.109674. PMID: 31526939
Role of allergen-specific T-follicular helper cells in immunotherapy.
Yao Y, Wang ZC, Yu D, Liu Z
Curr Opin Allergy Clin Immunol 2018 Dec;18(6):495-501. doi: 10.1097/ACI.0000000000000480. PMID: 30124489
Half-life of IgE in serum and skin: Consequences for anti-IgE therapy in patients with allergic disease.
Lawrence MG, Woodfolk JA, Schuyler AJ, Stillman LC, Chapman MD, Platts-Mills TA
J Allergy Clin Immunol 2017 Feb;139(2):422-428.e4. Epub 2016 Jul 14 doi: 10.1016/j.jaci.2016.04.056. PMID: 27496596Free PMC Article
Mechanisms of allergen-specific immunotherapy.
Akdis M, Akdis CA
J Allergy Clin Immunol 2007 Apr;119(4):780-91. Epub 2007 Feb 26 doi: 10.1016/j.jaci.2007.01.022. PMID: 17321578
Risk and safety of immunotherapy.
Rogala B
Allergy 1998 May;53(5):473-6. doi: 10.1111/j.1398-9995.1998.tb04083.x. PMID: 9636805

Prognosis

Induction of IgG(2) and IgG(4) B-cell memory following sublingual immunotherapy for ryegrass pollen allergy.
Heeringa JJ, McKenzie CI, Varese N, Hew M, Bakx ATCM, Aui PM, Rolland JM, O'Hehir RE, van Zelm MC
Allergy 2020 May;75(5):1121-1132. Epub 2019 Nov 4 doi: 10.1111/all.14073. PMID: 31587307Free PMC Article
DNA methylation and childhood asthma in the inner city.
Yang IV, Pedersen BS, Liu A, O'Connor GT, Teach SJ, Kattan M, Misiak RT, Gruchalla R, Steinbach SF, Szefler SJ, Gill MA, Calatroni A, David G, Hennessy CE, Davidson EJ, Zhang W, Gergen P, Togias A, Busse WW, Schwartz DA
J Allergy Clin Immunol 2015 Jul;136(1):69-80. Epub 2015 Mar 11 doi: 10.1016/j.jaci.2015.01.025. PMID: 25769910Free PMC Article
Local IgE in non-allergic rhinitis.
Campo P, Rondón C, Gould HJ, Barrionuevo E, Gevaert P, Blanca M
Clin Exp Allergy 2015 May;45(5):872-881. doi: 10.1111/cea.12476. PMID: 25495772
Urticaria and urticaria related skin condition/disease in children.
Novembre E, Cianferoni A, Mori F, Barni S, Calogero C, Bernardini R, Di Grande L, Pucci N, Azzari C, Vierucci A
Eur Ann Allergy Clin Immunol 2008 May;40(1):5-13. PMID: 18700329
Allergen-specific IgE in circulating immune complexes in patients with inhalant allergy undergoing specific immunotherapy.
Rogala B, Glück J
J Investig Allergol Clin Immunol 1999 May-Jun;9(3):183-9. PMID: 10412681

Clinical prediction guides

Alcohol consumption alters anti-Strongyloides stercoralis antibodies production.
De Souza JN, Cruz ADV, Araújo WAC, Sampaio LM, Allegretti SM, Teixeira MCA, Handali S, Galvão-Castro B, Soares NM
Immunobiology 2020 Mar;225(2):151898. Epub 2019 Dec 12 doi: 10.1016/j.imbio.2019.151898. PMID: 31902530
Anti-IgE Significantly Changes Circulating Interleukin-25, Vitamin-D and Interleukin-33 Levels in Patients with Allergic Asthma.
Yalcin AD, Uzun R
Curr Pharm Des 2019;25(35):3784-3795. doi: 10.2174/1381612825666190930095725. PMID: 31566129
Anti-IgE treatment in allergic rhinitis.
Bayar Muluk N, Bafaqeeh SA, Cingi C
Int J Pediatr Otorhinolaryngol 2019 Dec;127:109674. Epub 2019 Sep 10 doi: 10.1016/j.ijporl.2019.109674. PMID: 31526939
Multi-Method Molecular Characterisation of Human Dust-Mite-associated Allergic Asthma.
Whittle E, Leonard MO, Gant TW, Tonge DP
Sci Rep 2019 Jun 20;9(1):8912. doi: 10.1038/s41598-019-45257-1. PMID: 31221987Free PMC Article
Identification of galectin-3 as an autoantigen in patients with IgG(4)-related disease.
Perugino CA, AlSalem SB, Mattoo H, Della-Torre E, Mahajan V, Ganesh G, Allard-Chamard H, Wallace Z, Montesi SB, Kreuzer J, Haas W, Stone JH, Pillai S
J Allergy Clin Immunol 2019 Feb;143(2):736-745.e6. Epub 2018 May 29 doi: 10.1016/j.jaci.2018.05.011. PMID: 29852256Free PMC Article

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