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Reduced terminal:vellus ratio

MedGen UID:
1706135
•Concept ID:
C5139385
•
Finding
HPO: HP:0032497

Definition

A terminal:vellus ratio under 4:1 is characteristic of androgenetic alopecia. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVReduced terminal:vellus ratio

Conditions with this feature

Congenital hypotrichosis with juvenile macular dystrophy
MedGen UID:
316921
•Concept ID:
C1832162
•
Disease or Syndrome
Hypotrichosis with juvenile macular degeneration (HJMD) is a very rare syndrome characterized by sparse and short hair from birth followed by progressive macular degeneration leading to blindness.
See: Condition Record
Congenital hypotrichosis with juvenile macular dystrophy

Recent clinical studies

Etiology

Topical odorant application of the specific olfactory receptor OR2AT4 agonist, Sandalore(®) , improves telogen effluvium-associated parameters.
Jimenez F, López E, Bertolini M, Alam M, Chéret J, Westgate G, Rinaldi F, Marzani B, Paus R
J Cosmet Dermatol 2021 Mar;20(3):784-791. Epub 2020 Jul 29 doi: 10.1111/jocd.13608. PMID: 32645251
Characteristic findings by phototrichogram in southern Chinese women with Female pattern hair loss.
Mai W, Sun Y, Liu X, Lin D, Lu D
Skin Res Technol 2019 Jul;25(4):447-455. Epub 2019 Jan 7 doi: 10.1111/srt.12672. PMID: 30614573

Therapy

Topical odorant application of the specific olfactory receptor OR2AT4 agonist, Sandalore(®) , improves telogen effluvium-associated parameters.
Jimenez F, López E, Bertolini M, Alam M, Chéret J, Westgate G, Rinaldi F, Marzani B, Paus R
J Cosmet Dermatol 2021 Mar;20(3):784-791. Epub 2020 Jul 29 doi: 10.1111/jocd.13608. PMID: 32645251
The Effect of Plasma Rich in Growth Factors on Pattern Hair Loss: A Pilot Study.
Anitua E, Pino A, Martinez N, Orive G, Berridi D
Dermatol Surg 2017 May;43(5):658-670. doi: 10.1097/DSS.0000000000001049. PMID: 28221183

Clinical prediction guides

Topical odorant application of the specific olfactory receptor OR2AT4 agonist, Sandalore(®) , improves telogen effluvium-associated parameters.
Jimenez F, López E, Bertolini M, Alam M, Chéret J, Westgate G, Rinaldi F, Marzani B, Paus R
J Cosmet Dermatol 2021 Mar;20(3):784-791. Epub 2020 Jul 29 doi: 10.1111/jocd.13608. PMID: 32645251
Characteristic findings by phototrichogram in southern Chinese women with Female pattern hair loss.
Mai W, Sun Y, Liu X, Lin D, Lu D
Skin Res Technol 2019 Jul;25(4):447-455. Epub 2019 Jan 7 doi: 10.1111/srt.12672. PMID: 30614573
The Effect of Plasma Rich in Growth Factors on Pattern Hair Loss: A Pilot Study.
Anitua E, Pino A, Martinez N, Orive G, Berridi D
Dermatol Surg 2017 May;43(5):658-670. doi: 10.1097/DSS.0000000000001049. PMID: 28221183

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