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Invasive Adenocarcinoma in Adenomatous Polyp

MedGen UID:
1707342
•Concept ID:
C5206628
•
Neoplastic Process

Definition

An invasive adenocarcinoma that arises in an adenomatous polyp. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVInvasive Adenocarcinoma in Adenomatous Polyp

Professional guidelines

PubMed

Bowel cancer screening-generated diagnostic conundrum of the century: pseudoinvasion in sigmoid colonic polyps.
Shepherd NA, Griggs RK
Mod Pathol 2015 Jan;28 Suppl 1:S88-94. doi: 10.1038/modpathol.2014.138. PMID: 25560603
Small bowel adenocarcinoma: epidemiology, risk factors, diagnosis and treatment.
Aparicio T, Zaanan A, Svrcek M, Laurent-Puig P, Carrere N, Manfredi S, Locher C, Afchain P
Dig Liver Dis 2014 Feb;46(2):97-104. Epub 2013 Jun 21 doi: 10.1016/j.dld.2013.04.013. PMID: 23796552
Management of advanced duodenal polyposis in familial adenomatous polyposis.
Soravia C, Berk T, Haber G, Cohen Z, Gallinger S
J Gastrointest Surg 1997 Sep-Oct;1(5):474-8. doi: 10.1016/s1091-255x(97)80136-9. PMID: 9834381

Recent clinical studies

Etiology

Histologic Evaluation of Malignant Polyps and Low-Stage Colorectal Carcinoma.
Hagen CE, Farooq A
Arch Pathol Lab Med 2019 Dec;143(12):1450-1454. Epub 2019 Sep 11 doi: 10.5858/arpa.2019-0291-RA. PMID: 31509454
Serrated and non-serrated precursor lesions of colorectal cancer.
Langner C
Dig Dis 2015;33(1):28-37. Epub 2014 Dec 17 doi: 10.1159/000366032. PMID: 25531494
Small bowel adenocarcinoma: epidemiology, risk factors, diagnosis and treatment.
Aparicio T, Zaanan A, Svrcek M, Laurent-Puig P, Carrere N, Manfredi S, Locher C, Afchain P
Dig Liver Dis 2014 Feb;46(2):97-104. Epub 2013 Jun 21 doi: 10.1016/j.dld.2013.04.013. PMID: 23796552
Pulmonary preinvasive neoplasia.
Kerr KM
J Clin Pathol 2001 Apr;54(4):257-71. doi: 10.1136/jcp.54.4.257. PMID: 11304841Free PMC Article
Colonoscopic polypectomy.
Leaverton GH, Haun TM, Meihoff WE
Am Surg 1976 Jul;42(7):449-54. PMID: 937851

Diagnosis

Histopathological features for coexistent invasive cancer in large colorectal adenomatous polyps.
Emmanuel A, Haji A, Gulati S, Moorhead J, Papagrigoriadis S, Hayee B, Diaz-Cano S
BJS Open 2021 May 7;5(3) doi: 10.1093/bjsopen/zraa053. PMID: 34131706Free PMC Article
The pathology of bowel cancer screening.
Loughrey MB, Shepherd NA
Histopathology 2015 Jan;66(1):66-77. doi: 10.1111/his.12530. PMID: 25123305
Small bowel adenocarcinoma: epidemiology, risk factors, diagnosis and treatment.
Aparicio T, Zaanan A, Svrcek M, Laurent-Puig P, Carrere N, Manfredi S, Locher C, Afchain P
Dig Liver Dis 2014 Feb;46(2):97-104. Epub 2013 Jun 21 doi: 10.1016/j.dld.2013.04.013. PMID: 23796552
Management of early rectal cancer.
Tytherleigh MG, Warren BF, Mortensen NJ
Br J Surg 2008 Apr;95(4):409-23. doi: 10.1002/bjs.6127. PMID: 18314929
Colonoscopic polypectomy.
Leaverton GH, Haun TM, Meihoff WE
Am Surg 1976 Jul;42(7):449-54. PMID: 937851

Therapy

Endoscopic ampullectomy for non-invasive ampullary lesions: a single-center 10-year retrospective cohort study.
Lee R, Huelsen A, Gupta S, Hourigan LF
Surg Endosc 2021 Feb;35(2):684-692. Epub 2020 Mar 25 doi: 10.1007/s00464-020-07433-7. PMID: 32215745
Adenocarcinoma at the Ileostomy Site After a Proctocolectomy for Ulcerative Colitis and/or Familial Adenomatous Polyposis: An Overview.
James SD, Hawkins AT, M'Koma AE
Ostomy Wound Manage 2018 Jun;64(6):30-40. PMID: 30059346Free PMC Article
Management of malignant colon polyps: current status and controversies.
Aarons CB, Shanmugan S, Bleier JI
World J Gastroenterol 2014 Nov 21;20(43):16178-83. doi: 10.3748/wjg.v20.i43.16178. PMID: 25473171Free PMC Article
Small bowel adenocarcinoma: epidemiology, risk factors, diagnosis and treatment.
Aparicio T, Zaanan A, Svrcek M, Laurent-Puig P, Carrere N, Manfredi S, Locher C, Afchain P
Dig Liver Dis 2014 Feb;46(2):97-104. Epub 2013 Jun 21 doi: 10.1016/j.dld.2013.04.013. PMID: 23796552
Aspirin and other nonsteroidal anti-inflammatory agents in the prevention of colorectal cancer.
Sandler RS
Important Adv Oncol 1996:123-37. PMID: 8791132

Prognosis

Histopathological features for coexistent invasive cancer in large colorectal adenomatous polyps.
Emmanuel A, Haji A, Gulati S, Moorhead J, Papagrigoriadis S, Hayee B, Diaz-Cano S
BJS Open 2021 May 7;5(3) doi: 10.1093/bjsopen/zraa053. PMID: 34131706Free PMC Article
Histologic Evaluation of Malignant Polyps and Low-Stage Colorectal Carcinoma.
Hagen CE, Farooq A
Arch Pathol Lab Med 2019 Dec;143(12):1450-1454. Epub 2019 Sep 11 doi: 10.5858/arpa.2019-0291-RA. PMID: 31509454
Management of malignant colon polyps: current status and controversies.
Aarons CB, Shanmugan S, Bleier JI
World J Gastroenterol 2014 Nov 21;20(43):16178-83. doi: 10.3748/wjg.v20.i43.16178. PMID: 25473171Free PMC Article
Small bowel adenocarcinoma: epidemiology, risk factors, diagnosis and treatment.
Aparicio T, Zaanan A, Svrcek M, Laurent-Puig P, Carrere N, Manfredi S, Locher C, Afchain P
Dig Liver Dis 2014 Feb;46(2):97-104. Epub 2013 Jun 21 doi: 10.1016/j.dld.2013.04.013. PMID: 23796552
Management of early rectal cancer.
Tytherleigh MG, Warren BF, Mortensen NJ
Br J Surg 2008 Apr;95(4):409-23. doi: 10.1002/bjs.6127. PMID: 18314929

Clinical prediction guides

Enrichment of Prevotella intermedia in human colorectal cancer and its additive effects with Fusobacterium nucleatum on the malignant transformation of colorectal adenomas.
Lo CH, Wu DC, Jao SW, Wu CC, Lin CY, Chuang CH, Lin YB, Chen CH, Chen YT, Chen JH, Hsiao KH, Chen YJ, Chen YT, Wang JY, Li LH
J Biomed Sci 2022 Oct 27;29(1):88. doi: 10.1186/s12929-022-00869-0. PMID: 36303164Free PMC Article
The Adaptive Immune Landscape of the Colorectal Adenoma-Carcinoma Sequence.
Freitas JA, Gullo I, Garcia D, Miranda S, Spaans L, Pinho L, Reis J, Sousa F, Baptista M, Resende C, Leitão D, Durães C, Costa JL, Carneiro F, Machado JC
Int J Mol Sci 2021 Sep 10;22(18) doi: 10.3390/ijms22189791. PMID: 34575971Free PMC Article
Histopathological features for coexistent invasive cancer in large colorectal adenomatous polyps.
Emmanuel A, Haji A, Gulati S, Moorhead J, Papagrigoriadis S, Hayee B, Diaz-Cano S
BJS Open 2021 May 7;5(3) doi: 10.1093/bjsopen/zraa053. PMID: 34131706Free PMC Article
Cribriform-morular variant of thyroid carcinoma: a neoplasm with distinctive phenotype associated with the activation of the WNT/β-catenin pathway.
Cameselle-Teijeiro JM, Peteiro-González D, Caneiro-Gómez J, Sánchez-Ares M, Abdulkader I, Eloy C, Melo M, Amendoeira I, Soares P, Sobrinho-Simões M
Mod Pathol 2018 Aug;31(8):1168-1179. Epub 2018 May 21 doi: 10.1038/s41379-018-0070-2. PMID: 29785019
Characteristics and Clinical Outcomes of Duodenal Neoplasia in Japanese Patients With Familial Adenomatous Polyposis.
Yachida T, Nakajima T, Nonaka S, Nakamura K, Suzuki H, Yoshinaga S, Oda I, Moriya Y, Masaki T, Saito Y
J Clin Gastroenterol 2017 May/Jun;51(5):407-411. doi: 10.1097/MCG.0000000000000555. PMID: 27306941

Recent systematic reviews

Risk Factors for Non-Ampullary Duodenal Adenocarcinoma: A Systematic Review.
Yabuuchi Y, Yoshida M, Kakushima N, Kato M, Iguchi M, Yamamoto Y, Kanetaka K, Uraoka T, Fujishiro M, Sho M; Japan Duodenal Cancer Committee
Dig Dis 2022;40(2):147-155. Epub 2021 Apr 22 doi: 10.1159/000516561. PMID: 34000722

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