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Oligometastatic Esophageal Adenocarcinoma

MedGen UID:
1709233
•Concept ID:
C5237719
•
Neoplastic Process

Definition

Esophageal adenocarcinoma that has metastasized to a limited number of sites. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOligometastatic Esophageal Adenocarcinoma

Professional guidelines

PubMed

Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer: A Delphi consensus study in Europe.
Kroese TE, van Laarhoven HWM, Schoppman SF, Deseyne PRAJ, van Cutsem E, Haustermans K, Nafteux P, Thomas M, Obermannova R, Mortensen HR, Nordsmark M, Pfeiffer P, Elme A, Adenis A, Piessen G, Bruns CJ, Lordick F, Gockel I, Moehler M, Gani C, Liakakos T, Reynolds J, Morganti AG, Rosati R, Castoro C, Cellini F, D'Ugo D, Roviello F, Bencivenga M, de Manzoni G, van Berge Henegouwen MI, Hulshof MCCM, van Dieren J, Vollebergh M, van Sandick JW, Jeene P, Muijs CT, Slingerland M, Voncken FEM, Hartgrink H, Creemers GJ, van der Sangen MJC, Nieuwenhuijzen G, Berbee M, Verheij M, Wijnhoven B, Beerepoot LV, Mohammad NH, Mook S, Ruurda JP, Kolodziejczyk P, Polkowski WP, Wyrwicz L, Alsina M, Pera M, Kanonnikoff TF, Cervantes A, Nilsson M, Monig S, Wagner AD, Guckenberger M, Griffiths EA, Smyth E, Hanna GB, Markar S, Chaudry MA, Hawkins MA, Cheong E, van Hillegersberg R, van Rossum PSN; OMEC collaborators
Eur J Cancer 2023 May;185:28-39. Epub 2023 Feb 24 doi: 10.1016/j.ejca.2023.02.015. PMID: 36947929

Recent clinical studies

Etiology

An International Multicenter Study Exploring Whether Surveillance After Esophageal Cancer Surgery Impacts Oncological and Quality of Life Outcomes (ENSURE).
Elliott JA, Markar SR, Klevebro F, Johar A, Goense L, Lagergren P, Zaninotto G, van Hillegersberg R, van Berge Henegouwen MI, Nilsson M, Hanna GB, Reynolds JV; ENSURE Study Group
Ann Surg 2023 May 1;277(5):e1035-e1044. Epub 2022 Jan 27 doi: 10.1097/SLA.0000000000005378. PMID: 35129466Free PMC Article
Incidence and survival of patients with oligometastatic esophagogastric cancer: A multicenter cohort study.
Kroese TE, Christ SM, van Rossum PSN, Burger MDL, Buijs GS, Mühlematter U, Andratschke N, Ruurda JP, Hüllner M, Gutschow CA, van Hillegersberg R, Guckenberger M
Radiother Oncol 2022 Aug;173:269-276. Epub 2022 Jun 24 doi: 10.1016/j.radonc.2022.06.012. PMID: 35753555
Metastasectomy or Stereotactic Body Radiation Therapy With or Without Systemic Therapy for Oligometastatic Esophagogastric Cancer.
Kroese TE, Buijs GS, Burger MDL, Ruurda JP, Mook S, Brosens LAA, van Rossum PSN, van Hillegersberg R
Ann Surg Oncol 2022 Aug;29(8):4848-4857. Epub 2022 Apr 5 doi: 10.1245/s10434-022-11541-0. PMID: 35381938Free PMC Article
Perioperative FLOT chemotherapy plus surgery for oligometastatic esophagogastric adenocarcinoma: surgical outcome and overall survival.
Runkel M, Verst R, Spiegelberg J, Fichtner-Feigl S, Hoeppner J, Glatz T
BMC Surg 2021 Jan 13;21(1):35. doi: 10.1186/s12893-020-01035-9. PMID: 33435947Free PMC Article
Phase I trial of everolimus in combination with thoracic radiotherapy in non-small-cell lung cancer.
Deutsch E, Le Péchoux C, Faivre L, Rivera S, Tao Y, Pignon JP, Angokai M, Bahleda R, Deandreis D, Angevin E, Hennequin C, Besse B, Levy A, Soria JC
Ann Oncol 2015 Jun;26(6):1223-1229. Epub 2015 Feb 20 doi: 10.1093/annonc/mdv105. PMID: 25701455

Diagnosis

Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer: A Delphi consensus study in Europe.
Kroese TE, van Laarhoven HWM, Schoppman SF, Deseyne PRAJ, van Cutsem E, Haustermans K, Nafteux P, Thomas M, Obermannova R, Mortensen HR, Nordsmark M, Pfeiffer P, Elme A, Adenis A, Piessen G, Bruns CJ, Lordick F, Gockel I, Moehler M, Gani C, Liakakos T, Reynolds J, Morganti AG, Rosati R, Castoro C, Cellini F, D'Ugo D, Roviello F, Bencivenga M, de Manzoni G, van Berge Henegouwen MI, Hulshof MCCM, van Dieren J, Vollebergh M, van Sandick JW, Jeene P, Muijs CT, Slingerland M, Voncken FEM, Hartgrink H, Creemers GJ, van der Sangen MJC, Nieuwenhuijzen G, Berbee M, Verheij M, Wijnhoven B, Beerepoot LV, Mohammad NH, Mook S, Ruurda JP, Kolodziejczyk P, Polkowski WP, Wyrwicz L, Alsina M, Pera M, Kanonnikoff TF, Cervantes A, Nilsson M, Monig S, Wagner AD, Guckenberger M, Griffiths EA, Smyth E, Hanna GB, Markar S, Chaudry MA, Hawkins MA, Cheong E, van Hillegersberg R, van Rossum PSN; OMEC collaborators
Eur J Cancer 2023 May;185:28-39. Epub 2023 Feb 24 doi: 10.1016/j.ejca.2023.02.015. PMID: 36947929
Incidence and survival of patients with oligometastatic esophagogastric cancer: A multicenter cohort study.
Kroese TE, Christ SM, van Rossum PSN, Burger MDL, Buijs GS, Mühlematter U, Andratschke N, Ruurda JP, Hüllner M, Gutschow CA, van Hillegersberg R, Guckenberger M
Radiother Oncol 2022 Aug;173:269-276. Epub 2022 Jun 24 doi: 10.1016/j.radonc.2022.06.012. PMID: 35753555
Perioperative FLOT chemotherapy plus surgery for oligometastatic esophagogastric adenocarcinoma: surgical outcome and overall survival.
Runkel M, Verst R, Spiegelberg J, Fichtner-Feigl S, Hoeppner J, Glatz T
BMC Surg 2021 Jan 13;21(1):35. doi: 10.1186/s12893-020-01035-9. PMID: 33435947Free PMC Article
Oligometastatic Gastroesophageal Adenocarcinoma: Molecular Pathophysiology and Current Therapeutic Approach.
Jung JO, Nienhüser H, Schleussner N, Schmidt T
Int J Mol Sci 2020 Jan 31;21(3) doi: 10.3390/ijms21030951. PMID: 32023907Free PMC Article
The role of surgery in advanced disease for esophageal and junctional cancer.
Mönig S, van Hootegem S, Chevallay M, Wijnhoven BPL
Best Pract Res Clin Gastroenterol 2018 Oct-Dec;36-37:91-96. Epub 2018 Nov 24 doi: 10.1016/j.bpg.2018.11.002. PMID: 30551863

Therapy

Incidence and survival of patients with oligometastatic esophagogastric cancer: A multicenter cohort study.
Kroese TE, Christ SM, van Rossum PSN, Burger MDL, Buijs GS, Mühlematter U, Andratschke N, Ruurda JP, Hüllner M, Gutschow CA, van Hillegersberg R, Guckenberger M
Radiother Oncol 2022 Aug;173:269-276. Epub 2022 Jun 24 doi: 10.1016/j.radonc.2022.06.012. PMID: 35753555
Perioperative FLOT chemotherapy plus surgery for oligometastatic esophagogastric adenocarcinoma: surgical outcome and overall survival.
Runkel M, Verst R, Spiegelberg J, Fichtner-Feigl S, Hoeppner J, Glatz T
BMC Surg 2021 Jan 13;21(1):35. doi: 10.1186/s12893-020-01035-9. PMID: 33435947Free PMC Article
Oligometastatic Gastroesophageal Adenocarcinoma: Molecular Pathophysiology and Current Therapeutic Approach.
Jung JO, Nienhüser H, Schleussner N, Schmidt T
Int J Mol Sci 2020 Jan 31;21(3) doi: 10.3390/ijms21030951. PMID: 32023907Free PMC Article
The role of surgery in advanced disease for esophageal and junctional cancer.
Mönig S, van Hootegem S, Chevallay M, Wijnhoven BPL
Best Pract Res Clin Gastroenterol 2018 Oct-Dec;36-37:91-96. Epub 2018 Nov 24 doi: 10.1016/j.bpg.2018.11.002. PMID: 30551863
Phase I trial of everolimus in combination with thoracic radiotherapy in non-small-cell lung cancer.
Deutsch E, Le Péchoux C, Faivre L, Rivera S, Tao Y, Pignon JP, Angokai M, Bahleda R, Deandreis D, Angevin E, Hennequin C, Besse B, Levy A, Soria JC
Ann Oncol 2015 Jun;26(6):1223-1229. Epub 2015 Feb 20 doi: 10.1093/annonc/mdv105. PMID: 25701455

Prognosis

Incidence and survival of patients with oligometastatic esophagogastric cancer: A multicenter cohort study.
Kroese TE, Christ SM, van Rossum PSN, Burger MDL, Buijs GS, Mühlematter U, Andratschke N, Ruurda JP, Hüllner M, Gutschow CA, van Hillegersberg R, Guckenberger M
Radiother Oncol 2022 Aug;173:269-276. Epub 2022 Jun 24 doi: 10.1016/j.radonc.2022.06.012. PMID: 35753555
Metastasectomy or Stereotactic Body Radiation Therapy With or Without Systemic Therapy for Oligometastatic Esophagogastric Cancer.
Kroese TE, Buijs GS, Burger MDL, Ruurda JP, Mook S, Brosens LAA, van Rossum PSN, van Hillegersberg R
Ann Surg Oncol 2022 Aug;29(8):4848-4857. Epub 2022 Apr 5 doi: 10.1245/s10434-022-11541-0. PMID: 35381938Free PMC Article
Perioperative FLOT chemotherapy plus surgery for oligometastatic esophagogastric adenocarcinoma: surgical outcome and overall survival.
Runkel M, Verst R, Spiegelberg J, Fichtner-Feigl S, Hoeppner J, Glatz T
BMC Surg 2021 Jan 13;21(1):35. doi: 10.1186/s12893-020-01035-9. PMID: 33435947Free PMC Article
Oligometastatic Gastroesophageal Adenocarcinoma: Molecular Pathophysiology and Current Therapeutic Approach.
Jung JO, Nienhüser H, Schleussner N, Schmidt T
Int J Mol Sci 2020 Jan 31;21(3) doi: 10.3390/ijms21030951. PMID: 32023907Free PMC Article
Fractionated stereotactic radiation therapy for adrenal metastases: contributing to local tumor control with low toxicity.
Burjakow K, Fietkau R, Putz F, Achterberg N, Lettmaier S, Knippen S
Strahlenther Onkol 2019 Mar;195(3):236-245. Epub 2018 Oct 29 doi: 10.1007/s00066-018-1390-3. PMID: 30374590

Clinical prediction guides

Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer: A Delphi consensus study in Europe.
Kroese TE, van Laarhoven HWM, Schoppman SF, Deseyne PRAJ, van Cutsem E, Haustermans K, Nafteux P, Thomas M, Obermannova R, Mortensen HR, Nordsmark M, Pfeiffer P, Elme A, Adenis A, Piessen G, Bruns CJ, Lordick F, Gockel I, Moehler M, Gani C, Liakakos T, Reynolds J, Morganti AG, Rosati R, Castoro C, Cellini F, D'Ugo D, Roviello F, Bencivenga M, de Manzoni G, van Berge Henegouwen MI, Hulshof MCCM, van Dieren J, Vollebergh M, van Sandick JW, Jeene P, Muijs CT, Slingerland M, Voncken FEM, Hartgrink H, Creemers GJ, van der Sangen MJC, Nieuwenhuijzen G, Berbee M, Verheij M, Wijnhoven B, Beerepoot LV, Mohammad NH, Mook S, Ruurda JP, Kolodziejczyk P, Polkowski WP, Wyrwicz L, Alsina M, Pera M, Kanonnikoff TF, Cervantes A, Nilsson M, Monig S, Wagner AD, Guckenberger M, Griffiths EA, Smyth E, Hanna GB, Markar S, Chaudry MA, Hawkins MA, Cheong E, van Hillegersberg R, van Rossum PSN; OMEC collaborators
Eur J Cancer 2023 May;185:28-39. Epub 2023 Feb 24 doi: 10.1016/j.ejca.2023.02.015. PMID: 36947929
An International Multicenter Study Exploring Whether Surveillance After Esophageal Cancer Surgery Impacts Oncological and Quality of Life Outcomes (ENSURE).
Elliott JA, Markar SR, Klevebro F, Johar A, Goense L, Lagergren P, Zaninotto G, van Hillegersberg R, van Berge Henegouwen MI, Nilsson M, Hanna GB, Reynolds JV; ENSURE Study Group
Ann Surg 2023 May 1;277(5):e1035-e1044. Epub 2022 Jan 27 doi: 10.1097/SLA.0000000000005378. PMID: 35129466Free PMC Article
Phase I trial of everolimus in combination with thoracic radiotherapy in non-small-cell lung cancer.
Deutsch E, Le Péchoux C, Faivre L, Rivera S, Tao Y, Pignon JP, Angokai M, Bahleda R, Deandreis D, Angevin E, Hennequin C, Besse B, Levy A, Soria JC
Ann Oncol 2015 Jun;26(6):1223-1229. Epub 2015 Feb 20 doi: 10.1093/annonc/mdv105. PMID: 25701455

Recent systematic reviews

Definition, diagnosis and treatment of oligometastatic oesophagogastric cancer: A Delphi consensus study in Europe.
Kroese TE, van Laarhoven HWM, Schoppman SF, Deseyne PRAJ, van Cutsem E, Haustermans K, Nafteux P, Thomas M, Obermannova R, Mortensen HR, Nordsmark M, Pfeiffer P, Elme A, Adenis A, Piessen G, Bruns CJ, Lordick F, Gockel I, Moehler M, Gani C, Liakakos T, Reynolds J, Morganti AG, Rosati R, Castoro C, Cellini F, D'Ugo D, Roviello F, Bencivenga M, de Manzoni G, van Berge Henegouwen MI, Hulshof MCCM, van Dieren J, Vollebergh M, van Sandick JW, Jeene P, Muijs CT, Slingerland M, Voncken FEM, Hartgrink H, Creemers GJ, van der Sangen MJC, Nieuwenhuijzen G, Berbee M, Verheij M, Wijnhoven B, Beerepoot LV, Mohammad NH, Mook S, Ruurda JP, Kolodziejczyk P, Polkowski WP, Wyrwicz L, Alsina M, Pera M, Kanonnikoff TF, Cervantes A, Nilsson M, Monig S, Wagner AD, Guckenberger M, Griffiths EA, Smyth E, Hanna GB, Markar S, Chaudry MA, Hawkins MA, Cheong E, van Hillegersberg R, van Rossum PSN; OMEC collaborators
Eur J Cancer 2023 May;185:28-39. Epub 2023 Feb 24 doi: 10.1016/j.ejca.2023.02.015. PMID: 36947929
Patients undergoing surgery for oligometastatic oesophageal cancer survive for more than 2 years: bootstrapping systematic review data.
Schizas D, Mylonas KS, Kapsampelis P, Bagias G, Katsaros I, Frountzas M, Hemmati P, Liakakos T
Interact Cardiovasc Thorac Surg 2020 Sep 1;31(3):299-304. doi: 10.1093/icvts/ivaa116. PMID: 32666121

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