Definition

Breast carcinoma caused by deleterious germline mutation in a gene of the BRCA family. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVBRCA-Associated Breast Carcinoma

Hereditary cancer
- BRCA-Associated Malignant Neoplasm
  - BRCA-Associated Breast Carcinoma
    - Metastatic BRCA-Associated Breast Carcinoma

Professional guidelines

PubMed

Appropriateness of breast-conserving treatment of breast carcinoma in women with germline mutations in BRCA1 or BRCA2: a clinic-based series.

Robson M, Svahn T, McCormick B, Borgen P, Hudis CA, Norton L, Offit K
Cancer 2005 Jan 1;103(1):44-51. doi: 10.1002/cncr.20728. PMID: 15558796

See all (1)

Recent clinical studies

Etiology

Breast-conserving surgery in BRCA1/2 mutation carriers: are we approaching an answer?

Garcia-Etienne CA, Barile M, Gentilini OD, Botteri E, Rotmensz N, Sagona A, Farante G, Galimberti V, Luini A, Veronesi P, Bonanni B
Ann Surg Oncol 2009 Dec;16(12):3380-7. doi: 10.1245/s10434-009-0638-7. PMID: 19649554

Appropriateness of breast-conserving treatment of breast carcinoma in women with germline mutations in BRCA1 or BRCA2: a clinic-based series.

Robson M, Svahn T, McCormick B, Borgen P, Hudis CA, Norton L, Offit K
Cancer 2005 Jan 1;103(1):44-51. doi: 10.1002/cncr.20728. PMID: 15558796

Breast imaging findings in women with BRCA1- and BRCA2-associated breast carcinoma.

Hamilton LJ, Evans AJ, Wilson AR, Scott N, Cornford EJ, Pinder SE, Khan HN, Macmillan RD
Clin Radiol 2004 Oct;59(10):895-902. doi: 10.1016/j.crad.2004.03.013. PMID: 15451348

Epithelial lesions in prophylactic mastectomy specimens from women with BRCA mutations.

Kauff ND, Brogi E, Scheuer L, Pathak DR, Borgen PI, Hudis CA, Offit K, Robson ME
Cancer 2003 Apr 1;97(7):1601-8. doi: 10.1002/cncr.11225. PMID: 12655515

See all (4)

Diagnosis

Breast-conserving surgery in BRCA1/2 mutation carriers: are we approaching an answer?

Garcia-Etienne CA, Barile M, Gentilini OD, Botteri E, Rotmensz N, Sagona A, Farante G, Galimberti V, Luini A, Veronesi P, Bonanni B
Ann Surg Oncol 2009 Dec;16(12):3380-7. doi: 10.1245/s10434-009-0638-7. PMID: 19649554

Breast imaging findings in women with BRCA1- and BRCA2-associated breast carcinoma.

Hamilton LJ, Evans AJ, Wilson AR, Scott N, Cornford EJ, Pinder SE, Khan HN, Macmillan RD
Clin Radiol 2004 Oct;59(10):895-902. doi: 10.1016/j.crad.2004.03.013. PMID: 15451348

Incidence of BRCA1 and BRCA2 mutations in young Korean breast cancer patients.

Choi DH, Lee MH, Bale AE, Carter D, Haffty BG
J Clin Oncol 2004 May 1;22(9):1638-45. doi: 10.1200/JCO.2004.04.179. PMID: 15117986

See all (3)

Therapy

Breast-conserving surgery in BRCA1/2 mutation carriers: are we approaching an answer?

Garcia-Etienne CA, Barile M, Gentilini OD, Botteri E, Rotmensz N, Sagona A, Farante G, Galimberti V, Luini A, Veronesi P, Bonanni B
Ann Surg Oncol 2009 Dec;16(12):3380-7. doi: 10.1245/s10434-009-0638-7. PMID: 19649554

See all (1)

Prognosis

Breast-conserving surgery in BRCA1/2 mutation carriers: are we approaching an answer?

Garcia-Etienne CA, Barile M, Gentilini OD, Botteri E, Rotmensz N, Sagona A, Farante G, Galimberti V, Luini A, Veronesi P, Bonanni B
Ann Surg Oncol 2009 Dec;16(12):3380-7. doi: 10.1245/s10434-009-0638-7. PMID: 19649554

Appropriateness of breast-conserving treatment of breast carcinoma in women with germline mutations in BRCA1 or BRCA2: a clinic-based series.

Robson M, Svahn T, McCormick B, Borgen P, Hudis CA, Norton L, Offit K
Cancer 2005 Jan 1;103(1):44-51. doi: 10.1002/cncr.20728. PMID: 15558796

See all (2)