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Focal neonatal sequential seizure

MedGen UID:
1711228
•Concept ID:
C5397832
•
Disease or Syndrome
HPO: HP:0032826

Definition

Focal neonatal electro-clinical sequential motor seizure is a type of neonatal electro-clinical seizure where the predominant feature cannot be detected because of seizures presenting with a variety of clinical and electrographic focal signs, often changing lateralization within or between seizures. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFocal neonatal sequential seizure

Professional guidelines

PubMed

Electroencephalographic criteria for nonconvulsive status epilepticus: synopsis and comprehensive survey.
Sutter R, Kaplan PW
Epilepsia 2012 Aug;53 Suppl 3:1-51. doi: 10.1111/j.1528-1167.2012.03593.x. PMID: 22862158

Recent clinical studies

Etiology

The ILAE classification of seizures and the epilepsies: Modification for seizures in the neonate. Position paper by the ILAE Task Force on Neonatal Seizures.
Pressler RM, Cilio MR, Mizrahi EM, Moshé SL, Nunes ML, Plouin P, Vanhatalo S, Yozawitz E, de Vries LS, Puthenveettil Vinayan K, Triki CC, Wilmshurst JM, Yamamoto H, Zuberi SM
Epilepsia 2021 Mar;62(3):615-628. Epub 2021 Feb 1 doi: 10.1111/epi.16815. PMID: 33522601
Tiagabine in clinical practice: effects on seizure control and behavior.
Vossler DG, Morris GL 3rd, Harden CL, Montouris G, Faught E, Kanner AM, Fix A, French JA; Postmarketing Antiepileptic Drug Survey (PADS) group study investigators
Epilepsy Behav 2013 Aug;28(2):211-6. Epub 2013 Jun 13 doi: 10.1016/j.yebeh.2013.05.006. PMID: 23770680
Clinical evolution of seizures: distribution across time of day and sleep/wakefulness cycle.
Sánchez Fernández I, Ramgopal S, Powell C, Gregas M, Zarowski M, Shah A, Vendrame M, Alexopoulos AV, Kothare SV, Loddenkemper T
J Neurol 2013 Feb;260(2):549-57. Epub 2012 Oct 2 doi: 10.1007/s00415-012-6675-3. PMID: 23052595
Neonatal intracranial aneurysm rupture treated by endovascular management: a case report.
Tai YP, Chou IC, Yang MS, Lin HC, Chiu HY, Kuo HT, Su BH, Tsai CH
Pediatr Neonatol 2010 Aug;51(4):249-251. doi: 10.1016/S1875-9572(10)60048-4. PMID: 20713292
Predictive value of sequential electroencephalogram (EEG) in neonates with seizures and its relation to neurological outcome.
Khan RL, Nunes ML, Garcias da Silva LF, da Costa JC
J Child Neurol 2008 Feb;23(2):144-50. Epub 2007 Dec 26 doi: 10.1177/0883073807308711. PMID: 18160554

Diagnosis

The ILAE classification of seizures and the epilepsies: Modification for seizures in the neonate. Position paper by the ILAE Task Force on Neonatal Seizures.
Pressler RM, Cilio MR, Mizrahi EM, Moshé SL, Nunes ML, Plouin P, Vanhatalo S, Yozawitz E, de Vries LS, Puthenveettil Vinayan K, Triki CC, Wilmshurst JM, Yamamoto H, Zuberi SM
Epilepsia 2021 Mar;62(3):615-628. Epub 2021 Feb 1 doi: 10.1111/epi.16815. PMID: 33522601
Clinical evolution of seizures: distribution across time of day and sleep/wakefulness cycle.
Sánchez Fernández I, Ramgopal S, Powell C, Gregas M, Zarowski M, Shah A, Vendrame M, Alexopoulos AV, Kothare SV, Loddenkemper T
J Neurol 2013 Feb;260(2):549-57. Epub 2012 Oct 2 doi: 10.1007/s00415-012-6675-3. PMID: 23052595
Electroencephalographic criteria for nonconvulsive status epilepticus: synopsis and comprehensive survey.
Sutter R, Kaplan PW
Epilepsia 2012 Aug;53 Suppl 3:1-51. doi: 10.1111/j.1528-1167.2012.03593.x. PMID: 22862158
Predictive value of sequential electroencephalogram (EEG) in neonates with seizures and its relation to neurological outcome.
Khan RL, Nunes ML, Garcias da Silva LF, da Costa JC
J Child Neurol 2008 Feb;23(2):144-50. Epub 2007 Dec 26 doi: 10.1177/0883073807308711. PMID: 18160554
The spectrum of the DiGeorge syndrome.
Conley ME, Beckwith JB, Mancer JF, Tenckhoff L
J Pediatr 1979 Jun;94(6):883-90. doi: 10.1016/s0022-3476(79)80207-3. PMID: 448529

Therapy

Tiagabine in clinical practice: effects on seizure control and behavior.
Vossler DG, Morris GL 3rd, Harden CL, Montouris G, Faught E, Kanner AM, Fix A, French JA; Postmarketing Antiepileptic Drug Survey (PADS) group study investigators
Epilepsy Behav 2013 Aug;28(2):211-6. Epub 2013 Jun 13 doi: 10.1016/j.yebeh.2013.05.006. PMID: 23770680
Focal status epilepticus as atypical presentation of pyridoxine-dependent epilepsy.
Yoshii A, Takeoka M, Kelly PJ, Krishnamoorthy KS
J Child Neurol 2005 Aug;20(8):696-8. doi: 10.1177/08830738050200081301. PMID: 16225819

Prognosis

Tiagabine in clinical practice: effects on seizure control and behavior.
Vossler DG, Morris GL 3rd, Harden CL, Montouris G, Faught E, Kanner AM, Fix A, French JA; Postmarketing Antiepileptic Drug Survey (PADS) group study investigators
Epilepsy Behav 2013 Aug;28(2):211-6. Epub 2013 Jun 13 doi: 10.1016/j.yebeh.2013.05.006. PMID: 23770680
Predictive value of sequential electroencephalogram (EEG) in neonates with seizures and its relation to neurological outcome.
Khan RL, Nunes ML, Garcias da Silva LF, da Costa JC
J Child Neurol 2008 Feb;23(2):144-50. Epub 2007 Dec 26 doi: 10.1177/0883073807308711. PMID: 18160554

Clinical prediction guides

Predictive value of sequential electroencephalogram (EEG) in neonates with seizures and its relation to neurological outcome.
Khan RL, Nunes ML, Garcias da Silva LF, da Costa JC
J Child Neurol 2008 Feb;23(2):144-50. Epub 2007 Dec 26 doi: 10.1177/0883073807308711. PMID: 18160554

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