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Nodular Sclerosis Classic Hodgkin Lymphoma, Syncytial Variant

MedGen UID:
1714683
•Concept ID:
C5235045
•
Neoplastic Process
Synonyms: Nodular Sclerosis Classical Hodgkin Lymphoma, Syncytial Variant; Nodular Sclerosis Hodgkin Lymphoma, Syncytial Variant

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNodular Sclerosis Classic Hodgkin Lymphoma, Syncytial Variant

Recent clinical studies

Etiology

Clinicopathological features of syncytial variant nodular sclerosis Hodgkin lymphoma.
Zhang Q, Kim DH, Xu Y, Wang W, Medeiros LJ
Hum Pathol 2022 Jan;119:105-113. Epub 2021 Nov 19 doi: 10.1016/j.humpath.2021.11.007. PMID: 34801601
Histology of pediatric classic Hodgkin lymphoma: From diagnosis to prognostic stratification.
Pizzi M, Tazzoli S, Carraro E, Chaviano F, Massano D, Lovisa F, Mussolin L, Todesco A, Biffi A, d'Amore ES, Pillon M, Rugge M
Pediatr Blood Cancer 2020 May;67(5):e28230. Epub 2020 Mar 5 doi: 10.1002/pbc.28230. PMID: 32134194
Syncytial Variant Nodular Sclerosis Classical Hodgkin Lymphoma in an Adolescent and Review of the Literature: A Unique Entity.
Al-Antary E, Jesudas R, George A, Poulik J, Savaşan S
J Pediatr Hematol Oncol 2019 Apr;41(3):e167-e170. doi: 10.1097/MPH.0000000000001245. PMID: 30028823

Diagnosis

Syncytial variant of nodular sclerosis Hodgkin lymphoma: an under-emphasized variant.
Wang W, Zhang Q, Medeiros LJ
Hum Pathol 2021 Nov;117:115-125. Epub 2021 May 28 doi: 10.1016/j.humpath.2021.05.008. PMID: 34058246
Histology of pediatric classic Hodgkin lymphoma: From diagnosis to prognostic stratification.
Pizzi M, Tazzoli S, Carraro E, Chaviano F, Massano D, Lovisa F, Mussolin L, Todesco A, Biffi A, d'Amore ES, Pillon M, Rugge M
Pediatr Blood Cancer 2020 May;67(5):e28230. Epub 2020 Mar 5 doi: 10.1002/pbc.28230. PMID: 32134194
Syncytial Variant Nodular Sclerosis Classical Hodgkin Lymphoma in an Adolescent and Review of the Literature: A Unique Entity.
Al-Antary E, Jesudas R, George A, Poulik J, Savaşan S
J Pediatr Hematol Oncol 2019 Apr;41(3):e167-e170. doi: 10.1097/MPH.0000000000001245. PMID: 30028823
GATA3 Immunohistochemical Staining in Hodgkin Lymphoma: Diagnostic Utility in Differentiating Classic Hodgkin Lymphoma From Nodular Lymphocyte Predominant Hodgkin Lymphoma and Other Mimicking Entities.
Kezlarian B, Alhyari M, Venkataraman G, Karner K, Inamdar KV, Menon MP
Appl Immunohistochem Mol Morphol 2019 Mar;27(3):180-184. doi: 10.1097/PAI.0000000000000581. PMID: 28877074
Syncytial Variant of Nodular Sclerosis Classical Hodgkin Lymphoma of the Terminal Ileum in a Patient with Longstanding Crohn's Disease.
Gibson B, Podoll MB, Baumgartner EM, Maley DH
Ann Clin Lab Sci 2016 Spring;46(2):219-21. PMID: 27098632

Therapy

Histology of pediatric classic Hodgkin lymphoma: From diagnosis to prognostic stratification.
Pizzi M, Tazzoli S, Carraro E, Chaviano F, Massano D, Lovisa F, Mussolin L, Todesco A, Biffi A, d'Amore ES, Pillon M, Rugge M
Pediatr Blood Cancer 2020 May;67(5):e28230. Epub 2020 Mar 5 doi: 10.1002/pbc.28230. PMID: 32134194
Nodular lymphocyte predominant Hodgkin lymphoma with clusters of LP Cells, acute inflammation, and fibrosis: a syncytial variant.
Drakos E, Rassidakis GZ, Leventaki V, Cotta CV, Vega F, Medeiros LJ
Am J Surg Pathol 2009 Nov;33(11):1725-31. doi: 10.1097/PAS.0b013e3181b27765. PMID: 19730363

Prognosis

Clinicopathological features of syncytial variant nodular sclerosis Hodgkin lymphoma.
Zhang Q, Kim DH, Xu Y, Wang W, Medeiros LJ
Hum Pathol 2022 Jan;119:105-113. Epub 2021 Nov 19 doi: 10.1016/j.humpath.2021.11.007. PMID: 34801601
Histology of pediatric classic Hodgkin lymphoma: From diagnosis to prognostic stratification.
Pizzi M, Tazzoli S, Carraro E, Chaviano F, Massano D, Lovisa F, Mussolin L, Todesco A, Biffi A, d'Amore ES, Pillon M, Rugge M
Pediatr Blood Cancer 2020 May;67(5):e28230. Epub 2020 Mar 5 doi: 10.1002/pbc.28230. PMID: 32134194
GATA3 Immunohistochemical Staining in Hodgkin Lymphoma: Diagnostic Utility in Differentiating Classic Hodgkin Lymphoma From Nodular Lymphocyte Predominant Hodgkin Lymphoma and Other Mimicking Entities.
Kezlarian B, Alhyari M, Venkataraman G, Karner K, Inamdar KV, Menon MP
Appl Immunohistochem Mol Morphol 2019 Mar;27(3):180-184. doi: 10.1097/PAI.0000000000000581. PMID: 28877074

Clinical prediction guides

GATA3 Immunohistochemical Staining in Hodgkin Lymphoma: Diagnostic Utility in Differentiating Classic Hodgkin Lymphoma From Nodular Lymphocyte Predominant Hodgkin Lymphoma and Other Mimicking Entities.
Kezlarian B, Alhyari M, Venkataraman G, Karner K, Inamdar KV, Menon MP
Appl Immunohistochem Mol Morphol 2019 Mar;27(3):180-184. doi: 10.1097/PAI.0000000000000581. PMID: 28877074

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