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Renal tubular herpes simplex virus inclusions

MedGen UID:
1716463
•Concept ID:
C5397956
•
Finding
HPO: HP:0032956

Definition

Renal tubular nuclear inclusions that stain positive for herpes simplex virus (HSV). HSV is typically associated with multinucleated giant cells with nuclear inclusions and may cause hemorrhagic interstitial nephritis. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRenal tubular herpes simplex virus inclusions

Recent clinical studies

Etiology

BK virus infection in AIDS.
Cubukcu-Dimopulo O, Greco A, Kumar A, Karluk D, Mittal K, Jagirdar J
Am J Surg Pathol 2000 Jan;24(1):145-9. doi: 10.1097/00000478-200001000-00019. PMID: 10632500

Diagnosis

Tubuloreticular inclusions in peritubular capillaries of renal allografts.
Lee JY, Song SH, Kim YS, Lim BJ, Kim SI, Kim MS, Jeong HJ
Pathol Res Pract 2017 Sep;213(9):1185-1190. Epub 2017 Jun 6 doi: 10.1016/j.prp.2017.06.009. PMID: 28647211
BK virus infection in AIDS.
Cubukcu-Dimopulo O, Greco A, Kumar A, Karluk D, Mittal K, Jagirdar J
Am J Surg Pathol 2000 Jan;24(1):145-9. doi: 10.1097/00000478-200001000-00019. PMID: 10632500
Systemic lupus erythematosus.
Jones JM, Martinez AJ, Joshi VV, McWilliams N
Arch Pathol 1975 Mar;99(3):152-7. PMID: 164172

Therapy

Update on acyclovir: oral therapy for herpesvirus infections.
True BL, Carter BL
Clin Pharm 1984 Nov-Dec;3(6):607-13. PMID: 6096075

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