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Resectable Lung Non-Small Cell Carcinoma

MedGen UID:
1718964
•Concept ID:
C5237442
•
Neoplastic Process

Definition

Lung non-small cell carcinoma that is amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVResectable Lung Non-Small Cell Carcinoma

Professional guidelines

PubMed

Radiation therapy in the management of medically inoperable carcinoma of the lung: results and implications for future treatment strategies.
Dosoretz DE, Katin MJ, Blitzer PH, Rubenstein JH, Salenius S, Rashid M, Dosani RA, Mestas G, Siegel AD, Chadha TT
Int J Radiat Oncol Biol Phys 1992;24(1):3-9. doi: 10.1016/0360-3016(92)91013-d. PMID: 1324899

Recent clinical studies

Etiology

Rapid Advances in Resectable Non-Small Cell Lung Cancer: A Narrative Review.
West HJ, Kim JY
JAMA Oncol 2024 Feb 1;10(2):249-255. doi: 10.1001/jamaoncol.2023.5276. PMID: 38153722
Moving Immunotherapy Into Early-Stage Lung Cancer.
Linehan A, Forde PM
Cancer J 2020 Nov/Dec;26(6):543-547. doi: 10.1097/PPO.0000000000000493. PMID: 33298726
Management of stage I and II nonsmall cell lung cancer.
McDonald F, De Waele M, Hendriks LE, Faivre-Finn C, Dingemans AC, Van Schil PE
Eur Respir J 2017 Jan;49(1) Epub 2017 Jan 3 doi: 10.1183/13993003.00764-2016. PMID: 28049169
Non-small cell lung cancer: when to offer sublobar resection.
Sihoe AD, Van Schil P
Lung Cancer 2014 Nov;86(2):115-20. Epub 2014 Sep 16 doi: 10.1016/j.lungcan.2014.09.004. PMID: 25249427
Management of centrally located non-small-cell carcinoma.
Backhus LM, Wood DE
Oncology (Williston Park) 2014 Mar;28(3):215-21. PMID: 24855729

Diagnosis

Advances in systemic therapy for non-small cell lung cancer.
Miller M, Hanna N
BMJ 2021 Nov 9;375:n2363. doi: 10.1136/bmj.n2363. PMID: 34753715
Resectable non-small cell lung cancer Adjuvant chemotherapy: slightly longer survival.
Prescrire Int 2016 Dec;25(177):299-301. PMID: 30758927
Stage III Non-small Cell Lung Cancer.
Rusch VW
Semin Respir Crit Care Med 2016 Oct;37(5):727-735. Epub 2016 Oct 12 doi: 10.1055/s-0036-1592112. PMID: 27732994
Management of centrally located non-small-cell carcinoma.
Backhus LM, Wood DE
Oncology (Williston Park) 2014 Mar;28(3):215-21. PMID: 24855729
Revised ESTS guidelines for preoperative mediastinal lymph node staging for non-small-cell lung cancer.
De Leyn P, Dooms C, Kuzdzal J, Lardinois D, Passlick B, Rami-Porta R, Turna A, Van Schil P, Venuta F, Waller D, Weder W, Zielinski M
Eur J Cardiothorac Surg 2014 May;45(5):787-98. Epub 2014 Feb 26 doi: 10.1093/ejcts/ezu028. PMID: 24578407

Therapy

Rapid Advances in Resectable Non-Small Cell Lung Cancer: A Narrative Review.
West HJ, Kim JY
JAMA Oncol 2024 Feb 1;10(2):249-255. doi: 10.1001/jamaoncol.2023.5276. PMID: 38153722
Preoperative and Postoperative Systemic Therapy for Operable Non-Small-Cell Lung Cancer.
Chaft JE, Shyr Y, Sepesi B, Forde PM
J Clin Oncol 2022 Feb 20;40(6):546-555. Epub 2022 Jan 5 doi: 10.1200/JCO.21.01589. PMID: 34985966Free PMC Article
Evolution of systemic therapy for stages I-III non-metastatic non-small-cell lung cancer.
Chaft JE, Rimner A, Weder W, Azzoli CG, Kris MG, Cascone T
Nat Rev Clin Oncol 2021 Sep;18(9):547-557. Epub 2021 Apr 28 doi: 10.1038/s41571-021-00501-4. PMID: 33911215Free PMC Article
Treatment of Non-small Cell Lung Cancer with EGFR-mutations.
Yoneda K, Imanishi N, Ichiki Y, Tanaka F
J UOEH 2019;41(2):153-163. doi: 10.7888/juoeh.41.153. PMID: 31292359
Preoperative chemotherapy for non-small-cell lung cancer: a systematic review and meta-analysis of individual participant data.
NSCLC Meta-analysis Collaborative Group
Lancet 2014 May 3;383(9928):1561-71. Epub 2014 Feb 25 doi: 10.1016/S0140-6736(13)62159-5. PMID: 24576776Free PMC Article

Prognosis

Clinicopathological and prognostic features of operable non-small cell lung cancer patients with diabetes mellitus.
Kaseda K, Hishida T, Masai K, Asakura K, Hayashi Y, Asamura H
J Surg Oncol 2021 Jan;123(1):332-341. Epub 2020 Oct 1 doi: 10.1002/jso.26243. PMID: 33002203
Resectable non-small cell lung cancer Adjuvant chemotherapy: slightly longer survival.
Prescrire Int 2016 Dec;25(177):299-301. PMID: 30758927
Stereotactic ablative radiotherapy (SABR) for non-small cell lung cancer.
Iyengar P, Westover K, Timmerman RD
Semin Respir Crit Care Med 2013 Dec;34(6):845-54. Epub 2013 Nov 20 doi: 10.1055/s-0033-1358554. PMID: 24258574
Chemotherapy for non-small-cell lung carcinoma: from a blanket approach to individual therapy.
Reungwetwattana T, Eadens MJ, Molina JR
Semin Respir Crit Care Med 2011 Feb;32(1):78-93. Epub 2011 Apr 15 doi: 10.1055/s-0031-1272872. PMID: 21500127
Randomized trial of lobectomy versus limited resection for T1 N0 non-small cell lung cancer. Lung Cancer Study Group.
Ginsberg RJ, Rubinstein LV
Ann Thorac Surg 1995 Sep;60(3):615-22; discussion 622-3. doi: 10.1016/0003-4975(95)00537-u. PMID: 7677489

Clinical prediction guides

Rapid Advances in Resectable Non-Small Cell Lung Cancer: A Narrative Review.
West HJ, Kim JY
JAMA Oncol 2024 Feb 1;10(2):249-255. doi: 10.1001/jamaoncol.2023.5276. PMID: 38153722
Safety and effectiveness of neoadjuvant PD-1 inhibitor (toripalimab) plus chemotherapy in stage II-III NSCLC (LungMate 002): an open-label, single-arm, phase 2 trial.
Zhu X, Sun L, Song N, He W, Xie B, Hu J, Zhang J, Yang J, Dai J, Bian D, Xia H, Sun F, Xiong A, Luo J, Zhang L, Yu H, Liu M, Liu H, Wang H, Zhang H, Chen C, Wu C, Duan L, Zhu Y, Zhang P, Jiang G
BMC Med 2022 Dec 30;20(1):493. doi: 10.1186/s12916-022-02696-4. PMID: 36581917Free PMC Article
Treatment Sequencing in Resectable Lung Cancer: The Good and the Bad of Adjuvant Versus Neoadjuvant Therapy.
Provencio M, Calvo V, Romero A, Spicer JD, Cruz-Bermúdez A
Am Soc Clin Oncol Educ Book 2022 Apr;42:1-18. doi: 10.1200/EDBK_358995. PMID: 35561296
Striking a balance: Surveillance of non-small cell lung cancer after resection.
Heiden BT, Subramanian MP, Puri V, Kozower BD
J Thorac Cardiovasc Surg 2021 Sep;162(3):680-684. Epub 2020 Dec 10 doi: 10.1016/j.jtcvs.2020.10.166. PMID: 33485663
Management of centrally located non-small-cell carcinoma.
Backhus LM, Wood DE
Oncology (Williston Park) 2014 Mar;28(3):215-21. PMID: 24855729

Recent systematic reviews

Neoadjuvant immunotherapy for advanced, resectable non-small cell lung cancer: A systematic review and meta-analysis.
Wu Y, Verma V, Gay CM, Chen Y, Liang F, Lin Q, Wang J, Zhang W, Hui Z, Zhao M, Wang J, Chang JY
Cancer 2023 Jul 1;129(13):1969-1985. Epub 2023 Mar 30 doi: 10.1002/cncr.34755. PMID: 36994945
PD-L1 expression and Tumor mutation burden as Pathological response biomarkers of Neoadjuvant immunotherapy for Early-stage Non-small cell lung cancer: A systematic review and meta-analysis.
Deng H, Zhao Y, Cai X, Chen H, Cheng B, Zhong R, Li F, Xiong S, Li J, Liu J, He J, Liang W
Crit Rev Oncol Hematol 2022 Feb;170:103582. Epub 2022 Jan 11 doi: 10.1016/j.critrevonc.2022.103582. PMID: 35031441
Treatment for Brain Metastases: ASCO-SNO-ASTRO Guideline.
Vogelbaum MA, Brown PD, Messersmith H, Brastianos PK, Burri S, Cahill D, Dunn IF, Gaspar LE, Gatson NTN, Gondi V, Jordan JT, Lassman AB, Maues J, Mohile N, Redjal N, Stevens G, Sulman E, van den Bent M, Wallace HJ, Weinberg JS, Zadeh G, Schiff D
J Clin Oncol 2022 Feb 10;40(5):492-516. Epub 2021 Dec 21 doi: 10.1200/JCO.21.02314. PMID: 34932393
Preoperative chemotherapy for non-small-cell lung cancer: a systematic review and meta-analysis of individual participant data.
NSCLC Meta-analysis Collaborative Group
Lancet 2014 May 3;383(9928):1561-71. Epub 2014 Feb 25 doi: 10.1016/S0140-6736(13)62159-5. PMID: 24576776Free PMC Article
International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma.
Travis WD, Brambilla E, Noguchi M, Nicholson AG, Geisinger KR, Yatabe Y, Beer DG, Powell CA, Riely GJ, Van Schil PE, Garg K, Austin JH, Asamura H, Rusch VW, Hirsch FR, Scagliotti G, Mitsudomi T, Huber RM, Ishikawa Y, Jett J, Sanchez-Cespedes M, Sculier JP, Takahashi T, Tsuboi M, Vansteenkiste J, Wistuba I, Yang PC, Aberle D, Brambilla C, Flieder D, Franklin W, Gazdar A, Gould M, Hasleton P, Henderson D, Johnson B, Johnson D, Kerr K, Kuriyama K, Lee JS, Miller VA, Petersen I, Roggli V, Rosell R, Saijo N, Thunnissen E, Tsao M, Yankelewitz D
J Thorac Oncol 2011 Feb;6(2):244-85. doi: 10.1097/JTO.0b013e318206a221. PMID: 21252716Free PMC Article

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