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Cisplatin-Induced Tinnitus

MedGen UID:
1720225
•Concept ID:
C5237234
•
Disease or Syndrome

Definition

Tinnitus that is caused by exposure to cisplatin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCisplatin-Induced Tinnitus

Professional guidelines

PubMed

Long-term ototoxicity in women after cisplatin treatment for ovarian germ cell cancer.
Skalleberg J, Solheim O, Fosså SD, Småstuen MC, Osnes T, Gundersen POM, Bunne M
Gynecol Oncol 2017 Apr;145(1):148-153. Epub 2017 Feb 12 doi: 10.1016/j.ygyno.2017.02.006. PMID: 28202195

Recent clinical studies

Etiology

Clinical and Genome-wide Analysis of Cisplatin-induced Tinnitus Implicates Novel Ototoxic Mechanisms.
El Charif O, Mapes B, Trendowski MR, Wheeler HE, Wing C, Dinh PC Jr, Frisina RD, Feldman DR, Hamilton RJ, Vaughn DJ, Fung C, Kollmannsberger C, Mushiroda T, Kubo M, Gamazon ER, Cox NJ, Huddart R, Ardeshir-Rouhani-Fard S, Monahan P, Fossa SD, Einhorn LH, Travis LB, Dolan ME
Clin Cancer Res 2019 Jul 1;25(13):4104-4116. Epub 2019 Apr 5 doi: 10.1158/1078-0432.CCR-18-3179. PMID: 30952644Free PMC Article
Increases in spontaneous neural activity in the hamster dorsal cochlear nucleus following cisplatin treatment: a possible basis for cisplatin-induced tinnitus.
Rachel JD, Kaltenbach JA, Janisse J
Hear Res 2002 Feb;164(1-2):206-14. doi: 10.1016/s0378-5955(02)00287-3. PMID: 11950539

Diagnosis

Clinical and Genome-wide Analysis of Cisplatin-induced Tinnitus Implicates Novel Ototoxic Mechanisms.
El Charif O, Mapes B, Trendowski MR, Wheeler HE, Wing C, Dinh PC Jr, Frisina RD, Feldman DR, Hamilton RJ, Vaughn DJ, Fung C, Kollmannsberger C, Mushiroda T, Kubo M, Gamazon ER, Cox NJ, Huddart R, Ardeshir-Rouhani-Fard S, Monahan P, Fossa SD, Einhorn LH, Travis LB, Dolan ME
Clin Cancer Res 2019 Jul 1;25(13):4104-4116. Epub 2019 Apr 5 doi: 10.1158/1078-0432.CCR-18-3179. PMID: 30952644Free PMC Article

Therapy

Clinical and Genome-wide Analysis of Cisplatin-induced Tinnitus Implicates Novel Ototoxic Mechanisms.
El Charif O, Mapes B, Trendowski MR, Wheeler HE, Wing C, Dinh PC Jr, Frisina RD, Feldman DR, Hamilton RJ, Vaughn DJ, Fung C, Kollmannsberger C, Mushiroda T, Kubo M, Gamazon ER, Cox NJ, Huddart R, Ardeshir-Rouhani-Fard S, Monahan P, Fossa SD, Einhorn LH, Travis LB, Dolan ME
Clin Cancer Res 2019 Jul 1;25(13):4104-4116. Epub 2019 Apr 5 doi: 10.1158/1078-0432.CCR-18-3179. PMID: 30952644Free PMC Article
Increases in spontaneous neural activity in the hamster dorsal cochlear nucleus following cisplatin treatment: a possible basis for cisplatin-induced tinnitus.
Rachel JD, Kaltenbach JA, Janisse J
Hear Res 2002 Feb;164(1-2):206-14. doi: 10.1016/s0378-5955(02)00287-3. PMID: 11950539

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