U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Refractory Anal Canal Squamous Cell Carcinoma

MedGen UID:
1729500
•Concept ID:
C5420151
•
Neoplastic Process

Definition

Anal canal squamous cell carcinoma that is resistant to treatment. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRefractory Anal Canal Squamous Cell Carcinoma

Professional guidelines

PubMed

The Management and Prevention of Anal Squamous Cell Carcinoma.
Eng C, Messick C, Glynne-Jones R
Am Soc Clin Oncol Educ Book 2019 Jan;39:216-225. Epub 2019 May 17 doi: 10.1200/EDBK_237433. PMID: 31099616

Recent clinical studies

Etiology

Relapsed refractory metastatic squamous cell cancer of anal canal in a patient with retroviral infection responding to cetuximab.
Lerner J, Michel M, Dasanu CA
J Oncol Pharm Pract 2020 Jun;26(4):1025-1028. Epub 2019 Nov 4 doi: 10.1177/1078155219884605. PMID: 31684821
The Management and Prevention of Anal Squamous Cell Carcinoma.
Eng C, Messick C, Glynne-Jones R
Am Soc Clin Oncol Educ Book 2019 Jan;39:216-225. Epub 2019 May 17 doi: 10.1200/EDBK_237433. PMID: 31099616
Nivolumab for previously treated unresectable metastatic anal cancer (NCI9673): a multicentre, single-arm, phase 2 study.
Morris VK, Salem ME, Nimeiri H, Iqbal S, Singh P, Ciombor K, Polite B, Deming D, Chan E, Wade JL, Xiao L, Bekaii-Saab T, Vence L, Blando J, Mahvash A, Foo WC, Ohaji C, Pasia M, Bland G, Ohinata A, Rogers J, Mehdizadeh A, Banks K, Lanman R, Wolff RA, Streicher H, Allison J, Sharma P, Eng C
Lancet Oncol 2017 Apr;18(4):446-453. Epub 2017 Feb 18 doi: 10.1016/S1470-2045(17)30104-3. PMID: 28223062Free PMC Article

Diagnosis

The Management and Prevention of Anal Squamous Cell Carcinoma.
Eng C, Messick C, Glynne-Jones R
Am Soc Clin Oncol Educ Book 2019 Jan;39:216-225. Epub 2019 May 17 doi: 10.1200/EDBK_237433. PMID: 31099616
The promise of immunotherapy in anal squamous cell carcinoma: a novel approach for an orphan disease.
Johnson B, Eng C
Clin Adv Hematol Oncol 2017 Dec;15(12):968-961. PMID: 29315288
Invasive squamous cell carcinoma arising in refractory perianal Bowen's disease in a HIV-positive individual.
Herat A, Shirato K, Damian DL, Finlayson R, Whitfeld M
Australas J Dermatol 2006 May;47(2):120-3. doi: 10.1111/j.1440-0960.2006.00246.x. PMID: 16637809

Therapy

Relapsed refractory metastatic squamous cell cancer of anal canal in a patient with retroviral infection responding to cetuximab.
Lerner J, Michel M, Dasanu CA
J Oncol Pharm Pract 2020 Jun;26(4):1025-1028. Epub 2019 Nov 4 doi: 10.1177/1078155219884605. PMID: 31684821
The Management and Prevention of Anal Squamous Cell Carcinoma.
Eng C, Messick C, Glynne-Jones R
Am Soc Clin Oncol Educ Book 2019 Jan;39:216-225. Epub 2019 May 17 doi: 10.1200/EDBK_237433. PMID: 31099616
The promise of immunotherapy in anal squamous cell carcinoma: a novel approach for an orphan disease.
Johnson B, Eng C
Clin Adv Hematol Oncol 2017 Dec;15(12):968-961. PMID: 29315288
Nivolumab for previously treated unresectable metastatic anal cancer (NCI9673): a multicentre, single-arm, phase 2 study.
Morris VK, Salem ME, Nimeiri H, Iqbal S, Singh P, Ciombor K, Polite B, Deming D, Chan E, Wade JL, Xiao L, Bekaii-Saab T, Vence L, Blando J, Mahvash A, Foo WC, Ohaji C, Pasia M, Bland G, Ohinata A, Rogers J, Mehdizadeh A, Banks K, Lanman R, Wolff RA, Streicher H, Allison J, Sharma P, Eng C
Lancet Oncol 2017 Apr;18(4):446-453. Epub 2017 Feb 18 doi: 10.1016/S1470-2045(17)30104-3. PMID: 28223062Free PMC Article
Cetuximab in refractory squamous cell carcinoma of the anal canal.
Rogers JE, Eng C
J Gastrointest Cancer 2014 Dec;45 Suppl 1:198-200. doi: 10.1007/s12029-014-9626-7. PMID: 24908401

Prognosis

Relapsed refractory metastatic squamous cell cancer of anal canal in a patient with retroviral infection responding to cetuximab.
Lerner J, Michel M, Dasanu CA
J Oncol Pharm Pract 2020 Jun;26(4):1025-1028. Epub 2019 Nov 4 doi: 10.1177/1078155219884605. PMID: 31684821
Nivolumab for previously treated unresectable metastatic anal cancer (NCI9673): a multicentre, single-arm, phase 2 study.
Morris VK, Salem ME, Nimeiri H, Iqbal S, Singh P, Ciombor K, Polite B, Deming D, Chan E, Wade JL, Xiao L, Bekaii-Saab T, Vence L, Blando J, Mahvash A, Foo WC, Ohaji C, Pasia M, Bland G, Ohinata A, Rogers J, Mehdizadeh A, Banks K, Lanman R, Wolff RA, Streicher H, Allison J, Sharma P, Eng C
Lancet Oncol 2017 Apr;18(4):446-453. Epub 2017 Feb 18 doi: 10.1016/S1470-2045(17)30104-3. PMID: 28223062Free PMC Article

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...