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t(2;12)

MedGen UID:
1732021
•Concept ID:
C5420255
•
Cell or Molecular Dysfunction

Definition

A cytogenetic abnormality that involves a translocation between chromosomes 2 and 12. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVt(2;12)

Professional guidelines

PubMed

Health complexity assessment in primary care: A validity and feasibility study of the INTERMED tool.
Oliveira CA, Weber B, Dos Santos JLF, Zucoloto ML, de Camargo LL, Zanetti ACG, Rzewuska M, de Azevedo-Marques JM
PLoS One 2022;17(2):e0263702. Epub 2022 Feb 18 doi: 10.1371/journal.pone.0263702. PMID: 35180262Free PMC Article
Pilot Study of "Less is More" Rezum for Treatment of BPH.
Aladesuru O, Amankwah K, Elterman D, Zorn KC, Bhojani N, Te A, Chughtai B
Urology 2022 Jul;165:256-260. Epub 2022 Feb 6 doi: 10.1016/j.urology.2022.01.039. PMID: 35139413
Is Thought Management a Resource for Functioning in Women with Fibromyalgia Irrespective of Pain Levels?
Catala P, Suso-Ribera C, Gutierrez L, Perez S, Lopez-Roig S, Peñacoba C
Pain Med 2021 Aug 6;22(8):1827-1836. doi: 10.1093/pm/pnab073. PMID: 33595650

Recent clinical studies

Etiology

Ictal Theta Power as an Electroconvulsive Therapy Safety Biomarker: A Pilot Study.
Miller J, Jones T, Upston J, Deng ZD, McClintock SM, Ryman S, Quinn D, Abbott CC
J ECT 2022 Jun 1;38(2):88-94. doi: 10.1097/YCT.0000000000000812. PMID: 35613008Free PMC Article
Blood Pressure Monitoring as a Digital Health Tool for Improving Diabetes Clinical Outcomes: Retrospective Real-world Study.
Fundoiano-Hershcovitz Y, Bacher D, Ritholz MD, Horwitz DL, Manejwala O, Goldstein P
J Med Internet Res 2022 Feb 8;24(2):e32923. doi: 10.2196/32923. PMID: 35133284Free PMC Article
Frailty Worsens Antidepressant Treatment Outcomes in Late Life Depression.
Brown PJ, Ciarleglio A, Roose SP, Garcia CM, Chung S, Alvarez J, Stein A, Gomez S, Rutherford BR
Am J Geriatr Psychiatry 2021 Sep;29(9):944-955. Epub 2020 Dec 25 doi: 10.1016/j.jagp.2020.12.024. PMID: 33388223Free PMC Article
The Effect of Age on Binocular Vision Normative Values.
Sánchez-González MC, Sánchez-González JM, De-Hita-Cantalejo C, Vega-Holm M, Jiménez-Rejano JJ, Gutiérrez-Sánchez E
J Pediatr Ophthalmol Strabismus 2020 Nov 1;57(6):363-371. doi: 10.3928/01913913-20200622-01. PMID: 33211893
The role of bone marrow edema on osteochondral lesions of the talus.
D'Ambrosi R, Maccario C, Ursino C, Serra N, Usuelli FG
Foot Ankle Surg 2018 Jun;24(3):229-235. Epub 2017 Mar 6 doi: 10.1016/j.fas.2017.02.010. PMID: 29409254

Diagnosis

Frailty Worsens Antidepressant Treatment Outcomes in Late Life Depression.
Brown PJ, Ciarleglio A, Roose SP, Garcia CM, Chung S, Alvarez J, Stein A, Gomez S, Rutherford BR
Am J Geriatr Psychiatry 2021 Sep;29(9):944-955. Epub 2020 Dec 25 doi: 10.1016/j.jagp.2020.12.024. PMID: 33388223Free PMC Article
Cognitive-behavioral longitudinal assessment in ALS: the Italian Edinburgh Cognitive and Behavioral ALS screen (ECAS).
Poletti B, Solca F, Carelli L, Faini A, Madotto F, Lafronza A, Monti A, Zago S, Ciammola A, Ratti A, Ticozzi N, Abrahams S, Silani V
Amyotroph Lateral Scler Frontotemporal Degener 2018 Aug;19(5-6):387-395. Epub 2018 May 26 doi: 10.1080/21678421.2018.1473443. PMID: 29804470
Long-term neurophysiological and clinical response in patients with chronic inflammatory demyelinating polyradiculoneuropathy treated with subcutaneous immunoglobulin.
Cirillo G, Todisco V, Tedeschi G
Clin Neurophysiol 2018 May;129(5):967-973. Epub 2018 Feb 19 doi: 10.1016/j.clinph.2018.01.070. PMID: 29554579
The role of bone marrow edema on osteochondral lesions of the talus.
D'Ambrosi R, Maccario C, Ursino C, Serra N, Usuelli FG
Foot Ankle Surg 2018 Jun;24(3):229-235. Epub 2017 Mar 6 doi: 10.1016/j.fas.2017.02.010. PMID: 29409254
Molecular karyotyping of human single sperm by array- comparative genomic hybridization.
Patassini C, Garolla A, Bottacin A, Menegazzo M, Speltra E, Foresta C, Ferlin A
PLoS One 2013;8(4):e60922. Epub 2013 Apr 2 doi: 10.1371/journal.pone.0060922. PMID: 23565289Free PMC Article

Therapy

Ictal Theta Power as an Electroconvulsive Therapy Safety Biomarker: A Pilot Study.
Miller J, Jones T, Upston J, Deng ZD, McClintock SM, Ryman S, Quinn D, Abbott CC
J ECT 2022 Jun 1;38(2):88-94. doi: 10.1097/YCT.0000000000000812. PMID: 35613008Free PMC Article
Alcohol, Tobacco and Psychotropic Drugs Use Among a Population with Chronic Pain in Southern Spain. A Cross-Sectional Study.
Cáceres-Matos R, Gil-García E, Vázquez-Santiago S, Cabrera-León A
Pain Manag Nurs 2022 Aug;23(4):494-503. Epub 2021 Nov 30 doi: 10.1016/j.pmn.2021.10.006. PMID: 34857475
Frailty Worsens Antidepressant Treatment Outcomes in Late Life Depression.
Brown PJ, Ciarleglio A, Roose SP, Garcia CM, Chung S, Alvarez J, Stein A, Gomez S, Rutherford BR
Am J Geriatr Psychiatry 2021 Sep;29(9):944-955. Epub 2020 Dec 25 doi: 10.1016/j.jagp.2020.12.024. PMID: 33388223Free PMC Article
Smoking status and cognitive performance among vocational school students in Beijing, China.
Hu P, Huang L, Zhou S, Shi Q, Xiao D, Wang C
Respir Med 2018 Feb;135:8-11. Epub 2017 Dec 16 doi: 10.1016/j.rmed.2017.12.008. PMID: 29414456
The role of bone marrow edema on osteochondral lesions of the talus.
D'Ambrosi R, Maccario C, Ursino C, Serra N, Usuelli FG
Foot Ankle Surg 2018 Jun;24(3):229-235. Epub 2017 Mar 6 doi: 10.1016/j.fas.2017.02.010. PMID: 29409254

Prognosis

Ictal Theta Power as an Electroconvulsive Therapy Safety Biomarker: A Pilot Study.
Miller J, Jones T, Upston J, Deng ZD, McClintock SM, Ryman S, Quinn D, Abbott CC
J ECT 2022 Jun 1;38(2):88-94. doi: 10.1097/YCT.0000000000000812. PMID: 35613008Free PMC Article
Frailty Worsens Antidepressant Treatment Outcomes in Late Life Depression.
Brown PJ, Ciarleglio A, Roose SP, Garcia CM, Chung S, Alvarez J, Stein A, Gomez S, Rutherford BR
Am J Geriatr Psychiatry 2021 Sep;29(9):944-955. Epub 2020 Dec 25 doi: 10.1016/j.jagp.2020.12.024. PMID: 33388223Free PMC Article
The role of bone marrow edema on osteochondral lesions of the talus.
D'Ambrosi R, Maccario C, Ursino C, Serra N, Usuelli FG
Foot Ankle Surg 2018 Jun;24(3):229-235. Epub 2017 Mar 6 doi: 10.1016/j.fas.2017.02.010. PMID: 29409254
Predictors of early retirement after cancer rehabilitation-a longitudinal study.
Mehnert A, Barth J, Gaspar M, Leibbrand B, Kegel CD, Bootsveld W, Friedrich M, Hartung TJ, Berger D, Koch U
Eur J Cancer Care (Engl) 2017 Sep;26(5) Epub 2016 Jun 23 doi: 10.1111/ecc.12528. PMID: 27334307
Novel t(2;12)(q31;p13) in a case of pediatric T-cell acute lymphoblastic leukemia.
Parihar M, Gupta A, Remani AS, Bhattacharyya A, Mishra DK, Chandy M
J Pediatr Hematol Oncol 2014 Jul;36(5):e313-5. doi: 10.1097/MPH.0000000000000119. PMID: 24577543

Clinical prediction guides

Ictal Theta Power as an Electroconvulsive Therapy Safety Biomarker: A Pilot Study.
Miller J, Jones T, Upston J, Deng ZD, McClintock SM, Ryman S, Quinn D, Abbott CC
J ECT 2022 Jun 1;38(2):88-94. doi: 10.1097/YCT.0000000000000812. PMID: 35613008Free PMC Article
Smoking status and cognitive performance among vocational school students in Beijing, China.
Hu P, Huang L, Zhou S, Shi Q, Xiao D, Wang C
Respir Med 2018 Feb;135:8-11. Epub 2017 Dec 16 doi: 10.1016/j.rmed.2017.12.008. PMID: 29414456
The role of bone marrow edema on osteochondral lesions of the talus.
D'Ambrosi R, Maccario C, Ursino C, Serra N, Usuelli FG
Foot Ankle Surg 2018 Jun;24(3):229-235. Epub 2017 Mar 6 doi: 10.1016/j.fas.2017.02.010. PMID: 29409254
Childhood cognitive development in 22q11.2 deletion syndrome: case-control study.
Chawner SJRA, Doherty JL, Moss H, Niarchou M, Walters JTR, Owen MJ, van den Bree MBM
Br J Psychiatry 2017 Oct;211(4):223-230. Epub 2017 Sep 7 doi: 10.1192/bjp.bp.116.195651. PMID: 28882829Free PMC Article
Predictors of early retirement after cancer rehabilitation-a longitudinal study.
Mehnert A, Barth J, Gaspar M, Leibbrand B, Kegel CD, Bootsveld W, Friedrich M, Hartung TJ, Berger D, Koch U
Eur J Cancer Care (Engl) 2017 Sep;26(5) Epub 2016 Jun 23 doi: 10.1111/ecc.12528. PMID: 27334307

Supplemental Content

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