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Zoonotic Spillover

MedGen UID:
1740540
Concept ID:
C5400989
Disease or Syndrome
Synonyms: Spillovers, Zoonotic; Zoonotic Spillovers

Definition

Transmission of an infectious disease from a reservoir vertebrate population with a high pathogen prevalence coming into contact with a naive human population. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVZoonotic Spillover

Professional guidelines

PubMed

Nicastri E, Kobinger G, Vairo F, Montaldo C, Mboera LEG, Ansunama R, Zumla A, Ippolito G
Infect Dis Clin North Am 2019 Dec;33(4):953-976. doi: 10.1016/j.idc.2019.08.005. PMID: 31668200
Vairo F, Haider N, Kock R, Ntoumi F, Ippolito G, Zumla A
Infect Dis Clin North Am 2019 Dec;33(4):1003-1025. doi: 10.1016/j.idc.2019.08.006. PMID: 31668189
Hemachudha T, Ugolini G, Wacharapluesadee S, Sungkarat W, Shuangshoti S, Laothamatas J
Lancet Neurol 2013 May;12(5):498-513. doi: 10.1016/S1474-4422(13)70038-3. PMID: 23602163

Recent clinical studies

Etiology

Escudero-Pérez B, Lalande A, Mathieu C, Lawrence P
Viruses 2023 Feb 22;15(3) doi: 10.3390/v15030599. PMID: 36992308Free PMC Article
Keusch GT, Amuasi JH, Anderson DE, Daszak P, Eckerle I, Field H, Koopmans M, Lam SK, Das Neves CG, Peiris M, Perlman S, Wacharapluesadee S, Yadana S, Saif L
Proc Natl Acad Sci U S A 2022 Oct 18;119(42):e2202871119. Epub 2022 Oct 10 doi: 10.1073/pnas.2202871119. PMID: 36215506Free PMC Article
Milbank C, Vira B
Lancet Planet Health 2022 May;6(5):e439-e448. doi: 10.1016/S2542-5196(22)00064-X. PMID: 35550083Free PMC Article
Carlson CJ, Albery GF, Merow C, Trisos CH, Zipfel CM, Eskew EA, Olival KJ, Ross N, Bansal S
Nature 2022 Jul;607(7919):555-562. Epub 2022 Apr 28 doi: 10.1038/s41586-022-04788-w. PMID: 35483403
Ruiz-Aravena M, McKee C, Gamble A, Lunn T, Morris A, Snedden CE, Yinda CK, Port JR, Buchholz DW, Yeo YY, Faust C, Jax E, Dee L, Jones DN, Kessler MK, Falvo C, Crowley D, Bharti N, Brook CE, Aguilar HC, Peel AJ, Restif O, Schountz T, Parrish CR, Gurley ES, Lloyd-Smith JO, Hudson PJ, Munster VJ, Plowright RK
Nat Rev Microbiol 2022 May;20(5):299-314. Epub 2021 Nov 19 doi: 10.1038/s41579-021-00652-2. PMID: 34799704Free PMC Article

Diagnosis

Lieber CM, Aggarwal M, Yoon JJ, Cox RM, Kang HJ, Sourimant J, Toots M, Johnson SK, Jones CA, Sticher ZM, Kolykhalov AA, Saindane MT, Tompkins SM, Planz O, Painter GR, Natchus MG, Sakamoto K, Plemper RK
PLoS Pathog 2023 Apr;19(4):e1011342. Epub 2023 Apr 17 doi: 10.1371/journal.ppat.1011342. PMID: 37068076Free PMC Article
Bryer J, Freeman EE, Rosenbach M
J Am Acad Dermatol 2022 Nov;87(5):1069-1074. Epub 2022 Jul 8 doi: 10.1016/j.jaad.2022.07.007. PMID: 35817333Free PMC Article
Yadana S, Cheun-Arom T, Li H, Hagan E, Mendelsohn E, Latinne A, Martinez S, Putcharoen O, Homvijitkul J, Sathaporntheera O, Rattanapreeda N, Chartpituck P, Yamsakul S, Sutham K, Komolsiri S, Pornphatthananikhom S, Petcharat S, Ampoot W, Francisco L, Hemachudha T, Daszak P, Olival KJ, Wacharapluesadee S
BMC Infect Dis 2022 May 16;22(1):472. doi: 10.1186/s12879-022-07439-7. PMID: 35578171Free PMC Article
Das P, Sazzad HMS, Aleem MA, Rahman MZ, Rahman M, Anthony SJ, Lipkin WI, Gurley ES, Luby SP, Openshaw JJ
Philos Trans R Soc Lond B Biol Sci 2019 Sep 30;374(1782):20190019. Epub 2019 Aug 12 doi: 10.1098/rstb.2019.0019. PMID: 31401956Free PMC Article
Gossner C, Danielson N, Gervelmeyer A, Berthe F, Faye B, Kaasik Aaslav K, Adlhoch C, Zeller H, Penttinen P, Coulombier D
Zoonoses Public Health 2016 Feb;63(1):1-9. Epub 2014 Dec 27 doi: 10.1111/zph.12171. PMID: 25545147Free PMC Article

Therapy

Hamlet A, Ramos DG, Gaythorpe KAM, Romano APM, Garske T, Ferguson NM
Nat Commun 2021 Jun 15;12(1):3647. doi: 10.1038/s41467-021-23926-y. PMID: 34131128Free PMC Article
Huchting J
Antivir Chem Chemother 2020 Jan-Dec;28:2040206620976786. doi: 10.1177/2040206620976786. PMID: 33297724Free PMC Article
Léger E, Borlase A, Fall CB, Diouf ND, Diop SD, Yasenev L, Catalano S, Thiam CT, Ndiaye A, Emery A, Morrell A, Rabone M, Ndao M, Faye B, Rollinson D, Rudge JW, Sène M, Webster JP
Lancet Planet Health 2020 Aug;4(8):e330-e342. doi: 10.1016/S2542-5196(20)30129-7. PMID: 32800151Free PMC Article
Han BA, O'Regan SM, Paul Schmidt J, Drake JM
Ecol Lett 2020 Aug;23(8):1178-1188. Epub 2020 May 22 doi: 10.1111/ele.13520. PMID: 32441459Free PMC Article
Ponce L, Kinoshita R, Nishiura H
Math Biosci Eng 2019 Apr 11;16(4):3130-3143. doi: 10.3934/mbe.2019155. PMID: 31137254

Prognosis

Friant S
Evol Anthropol 2024 Apr;33(2):e22015. Epub 2023 Dec 21 doi: 10.1002/evan.22015. PMID: 38130075
Escudero-Pérez B, Lalande A, Mathieu C, Lawrence P
Viruses 2023 Feb 22;15(3) doi: 10.3390/v15030599. PMID: 36992308Free PMC Article
Carlson CJ, Albery GF, Merow C, Trisos CH, Zipfel CM, Eskew EA, Olival KJ, Ross N, Bansal S
Nature 2022 Jul;607(7919):555-562. Epub 2022 Apr 28 doi: 10.1038/s41586-022-04788-w. PMID: 35483403
Ruiz-Aravena M, McKee C, Gamble A, Lunn T, Morris A, Snedden CE, Yinda CK, Port JR, Buchholz DW, Yeo YY, Faust C, Jax E, Dee L, Jones DN, Kessler MK, Falvo C, Crowley D, Bharti N, Brook CE, Aguilar HC, Peel AJ, Restif O, Schountz T, Parrish CR, Gurley ES, Lloyd-Smith JO, Hudson PJ, Munster VJ, Plowright RK
Nat Rev Microbiol 2022 May;20(5):299-314. Epub 2021 Nov 19 doi: 10.1038/s41579-021-00652-2. PMID: 34799704Free PMC Article
Plowright RK, Parrish CR, McCallum H, Hudson PJ, Ko AI, Graham AL, Lloyd-Smith JO
Nat Rev Microbiol 2017 Aug;15(8):502-510. Epub 2017 May 30 doi: 10.1038/nrmicro.2017.45. PMID: 28555073Free PMC Article

Clinical prediction guides

Friant S
Evol Anthropol 2024 Apr;33(2):e22015. Epub 2023 Dec 21 doi: 10.1002/evan.22015. PMID: 38130075
Escudero-Pérez B, Lalande A, Mathieu C, Lawrence P
Viruses 2023 Feb 22;15(3) doi: 10.3390/v15030599. PMID: 36992308Free PMC Article
Carlson CJ, Albery GF, Merow C, Trisos CH, Zipfel CM, Eskew EA, Olival KJ, Ross N, Bansal S
Nature 2022 Jul;607(7919):555-562. Epub 2022 Apr 28 doi: 10.1038/s41586-022-04788-w. PMID: 35483403
Ruiz-Aravena M, McKee C, Gamble A, Lunn T, Morris A, Snedden CE, Yinda CK, Port JR, Buchholz DW, Yeo YY, Faust C, Jax E, Dee L, Jones DN, Kessler MK, Falvo C, Crowley D, Bharti N, Brook CE, Aguilar HC, Peel AJ, Restif O, Schountz T, Parrish CR, Gurley ES, Lloyd-Smith JO, Hudson PJ, Munster VJ, Plowright RK
Nat Rev Microbiol 2022 May;20(5):299-314. Epub 2021 Nov 19 doi: 10.1038/s41579-021-00652-2. PMID: 34799704Free PMC Article
Plowright RK, Parrish CR, McCallum H, Hudson PJ, Ko AI, Graham AL, Lloyd-Smith JO
Nat Rev Microbiol 2017 Aug;15(8):502-510. Epub 2017 May 30 doi: 10.1038/nrmicro.2017.45. PMID: 28555073Free PMC Article

Recent systematic reviews

Clifford Astbury C, Lee KM, Mcleod R, Aguiar R, Atique A, Balolong M, Clarke J, Demeshko A, Labonté R, Ruckert A, Sibal P, Togño KC, Viens AM, Wiktorowicz M, Yambayamba MK, Yau A, Penney TL
Global Health 2023 Nov 8;19(1):82. doi: 10.1186/s12992-023-00986-x. PMID: 37940941Free PMC Article
Sánchez CA, Venkatachalam-Vaz J, Drake JM
Zoonoses Public Health 2021 Sep;68(6):563-577. Epub 2021 May 20 doi: 10.1111/zph.12846. PMID: 34018336

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