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Pituitary gland basophil adenoma

MedGen UID:
1746
•Concept ID:
C0001431
•
Neoplastic Process
Synonyms: Adenoma, Basophil; Adenoma, Basophilic; Adenomas, Basophil; Adenomas, Basophilic; Basophil Adenoma; Basophil Adenomas; Basophilic Adenoma; Basophilic Adenomas
SNOMED CT: Basophil adenoma (9436005); Mucoid cell adenoma (9436005)
 
Monarch Initiative: MONDO:0006673

Definition

An epithelial neoplasm of the anterior pituitary gland in which the neoplastic cells stain positive with basic dyes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPituitary gland basophil adenoma

Professional guidelines

PubMed

Gamma Knife radiosurgery as a primary surgical treatment for hypersecreting pituitary adenomas.
Zhang N, Pan L, Dai J, Wang B, Wang E, Zhang W, Cai P
Stereotact Funct Neurosurg 2000;75(2-3):123-8. doi: 10.1159/000048393. PMID: 11740180
Transcranial management of pituitary tumours with suprasellar extension.
Symon L, Jakubowski J
J Neurol Neurosurg Psychiatry 1979 Feb;42(2):123-33. doi: 10.1136/jnnp.42.2.123. PMID: 217970Free PMC Article
Treatment of Nelson's syndrome by pituitary implantation of yttrium-90 or gold-198.
Cassar J, Doyle FH, Lewis PD, Mashiter K, Noorden S, Joplin GF
Br Med J 1976 Jul 31;2(6030):269-72. doi: 10.1136/bmj.2.6030.269. PMID: 182313Free PMC Article

Recent clinical studies

Etiology

Pre-operative serum inflammation-based scores in patients with pituitary adenomas.
Marques P, de Vries F, Dekkers OM, van Furth WR, Korbonits M, Biermasz NR, Pereira AM
Pituitary 2021 Jun;24(3):334-350. Epub 2020 Nov 24 doi: 10.1007/s11102-020-01112-5. PMID: 33230695
Silent pituitary plurihormonal adenoma: clinical relevance of immunohistochemical analysis.
García-Sáenz M, Uribe-Cortés D, González-Virla B, Mendoza-Zubieta V, Vargas-Ortega G
Rev Med Inst Mex Seguro Soc 2019 Apr 1;57(1):48-55. PMID: 31071255
VEGF, VEGF165b and EG-VEGF expression is specifically related with hormone profile in pituitary adenomas.
Corlan AS, Cîmpean AM, Melnic E, Raica M, Sarb S
Eur J Histochem 2019 Mar 5;63(1) doi: 10.4081/ejh.2019.3010. PMID: 30838843Free PMC Article
Aging and the human pituitary gland.
Sano T, Kovacs KT, Scheithauer BW, Young WF Jr
Mayo Clin Proc 1993 Oct;68(10):971-7. doi: 10.1016/s0025-6196(12)62269-1. PMID: 8412363
Histopathology of the pituitary.
Doniach I
Clin Endocrinol Metab 1985 Nov;14(4):765-89. doi: 10.1016/s0300-595x(85)80077-3. PMID: 3002676

Diagnosis

Silent pituitary plurihormonal adenoma: clinical relevance of immunohistochemical analysis.
García-Sáenz M, Uribe-Cortés D, González-Virla B, Mendoza-Zubieta V, Vargas-Ortega G
Rev Med Inst Mex Seguro Soc 2019 Apr 1;57(1):48-55. PMID: 31071255
Galectin-3 Expression in Functioning and Silent ACTH-Producing Adenomas.
Jin L, Riss D, Ruebel K, Kajita S, Scheithauer BW, Horvath E, Kovacs K, Lloyd RV
Endocr Pathol 2005 Summer;16(2):107-14. doi: 10.1385/ep:16:2:107. PMID: 16199895
The basophil adenomas of the pituitary body and their clinical manifestations (pituitary basophilism). 1932.
Cushing H
Obes Res 1994 Sep;2(5):486-508. doi: 10.1002/j.1550-8528.1994.tb00097.x. PMID: 16353601
An overview of pituitary tumors.
Berry RG, Caplan HJ
Ann Clin Lab Sci 1979 Mar-Apr;9(2):94-102. PMID: 222198
Cerebrospinal fluid rhinorrhea.
Charles DA, Snell D
Laryngoscope 1979 May;89(5 Pt 1):822-6. doi: 10.1288/00005537-197905000-00021. PMID: 221763

Therapy

Idiopathic Intracranial Hypertension After Surgical Treatment of Cushing Disease: Case Report and Review of Management Strategies.
Wagner J, Fleseriu CM, Ibrahim A, Cetas JS
World Neurosurg 2016 Dec;96:611.e15-611.e18. Epub 2016 Sep 12 doi: 10.1016/j.wneu.2016.09.008. PMID: 27633717
Gamma Knife radiosurgery as a primary surgical treatment for hypersecreting pituitary adenomas.
Zhang N, Pan L, Dai J, Wang B, Wang E, Zhang W, Cai P
Stereotact Funct Neurosurg 2000;75(2-3):123-8. doi: 10.1159/000048393. PMID: 11740180
Cyproheptadine-induced remission of Cushing's disease due to pituitary basophil adenoma.
Jimenez-Alonso J, Munoz-Avila J, Jaimez L, Pérez-Jimenez F, Bellido C, Jiménez-Perepérez JA
Drug Intell Clin Pharm 1982 Dec;16(12):962-5. doi: 10.1177/106002808201601213. PMID: 6295736
Heavy-particle therapy for acromegaly, Cushing's disease, Nelson's syndrome, and nonfunctioning pituitary adenomas.
Linfoot JA, Chong CY, Garcia JF, Cleveland AS, Connell GM, Manougian E, Okerlund MD, Born JL, Lawrence JH
Prog At Med 1971;3:219-38. PMID: 4335128
The value of radiation therapy for pituitary and parapituitary tumours.
Kramer S
Can Med Assoc J 1968 Dec 14;99(23):1120-7. PMID: 4302128Free PMC Article

Prognosis

Pre-operative serum inflammation-based scores in patients with pituitary adenomas.
Marques P, de Vries F, Dekkers OM, van Furth WR, Korbonits M, Biermasz NR, Pereira AM
Pituitary 2021 Jun;24(3):334-350. Epub 2020 Nov 24 doi: 10.1007/s11102-020-01112-5. PMID: 33230695
Silent pituitary plurihormonal adenoma: clinical relevance of immunohistochemical analysis.
García-Sáenz M, Uribe-Cortés D, González-Virla B, Mendoza-Zubieta V, Vargas-Ortega G
Rev Med Inst Mex Seguro Soc 2019 Apr 1;57(1):48-55. PMID: 31071255
VEGF, VEGF165b and EG-VEGF expression is specifically related with hormone profile in pituitary adenomas.
Corlan AS, Cîmpean AM, Melnic E, Raica M, Sarb S
Eur J Histochem 2019 Mar 5;63(1) doi: 10.4081/ejh.2019.3010. PMID: 30838843Free PMC Article
Cushing's case XLV: Minnie G.
Lanzino G, Maartens NF, Laws ER Jr
J Neurosurg 2002 Jul;97(1):231-4. doi: 10.3171/jns.2002.97.1.0231. PMID: 12134925
Galanin in human pituitary adenomas: frequency and clinical significance.
Leung B, Iisma TP, Leung KC, Hort YJ, Turner J, Sheehy JP, Ho KK
Clin Endocrinol (Oxf) 2002 Mar;56(3):397-403. doi: 10.1046/j.1365-2265.2002.01486.x. PMID: 11940053

Clinical prediction guides

Pre-operative serum inflammation-based scores in patients with pituitary adenomas.
Marques P, de Vries F, Dekkers OM, van Furth WR, Korbonits M, Biermasz NR, Pereira AM
Pituitary 2021 Jun;24(3):334-350. Epub 2020 Nov 24 doi: 10.1007/s11102-020-01112-5. PMID: 33230695
Silent pituitary plurihormonal adenoma: clinical relevance of immunohistochemical analysis.
García-Sáenz M, Uribe-Cortés D, González-Virla B, Mendoza-Zubieta V, Vargas-Ortega G
Rev Med Inst Mex Seguro Soc 2019 Apr 1;57(1):48-55. PMID: 31071255
Galanin in human pituitary adenomas: frequency and clinical significance.
Leung B, Iisma TP, Leung KC, Hort YJ, Turner J, Sheehy JP, Ho KK
Clin Endocrinol (Oxf) 2002 Mar;56(3):397-403. doi: 10.1046/j.1365-2265.2002.01486.x. PMID: 11940053
Immunohistochemical survey of migration of human anterior pituitary cells in developmental, pathological, and clinical aspects: a review.
Hori A, Schmidt D, Kuebber S
Microsc Res Tech 1999 Jul 1;46(1):59-68. doi: 10.1002/(SICI)1097-0029(19990701)46:1<59::AID-JEMT6>3.0.CO;2-S. PMID: 10402273
Aging and the human pituitary gland.
Sano T, Kovacs KT, Scheithauer BW, Young WF Jr
Mayo Clin Proc 1993 Oct;68(10):971-7. doi: 10.1016/s0025-6196(12)62269-1. PMID: 8412363

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