U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pituitary gland acidophil adenoma

MedGen UID:
1748
•Concept ID:
C0001433
•
Neoplastic Process
Synonyms: Acidophil Adenoma; Acidophil Adenomas; Acidophilic Adenoma; Acidophilic Adenomas; Adenoma, Acidophil; Adenoma, Acidophilic; Adenoma, Eosinophil; Adenoma, Eosinophilic; Adenomas, Acidophil; Adenomas, Acidophilic; Adenomas, Eosinophil; Adenomas, Eosinophilic; Eosinophil Adenoma; Eosinophil Adenomas; Eosinophilic Adenoma; Eosinophilic Adenomas
SNOMED CT: Acidophil adenoma (21109002); Eosinophil adenoma (21109002)
 
Monarch Initiative: MONDO:0006634

Definition

An epithelial neoplasm of the anterior pituitary gland in which the neoplastic cells stain positive with acidic dyes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPituitary gland acidophil adenoma

Professional guidelines

PubMed

Gamma Knife radiosurgery as a primary surgical treatment for hypersecreting pituitary adenomas.
Zhang N, Pan L, Dai J, Wang B, Wang E, Zhang W, Cai P
Stereotact Funct Neurosurg 2000;75(2-3):123-8. doi: 10.1159/000048393. PMID: 11740180
Pituitary surgery for the management of acromegaly.
Laws ER, Vance ML, Thapar K
Horm Res 2000;53 Suppl 3:71-5. doi: 10.1159/000023538. PMID: 10971109
Transcranial management of pituitary tumours with suprasellar extension.
Symon L, Jakubowski J
J Neurol Neurosurg Psychiatry 1979 Feb;42(2):123-33. doi: 10.1136/jnnp.42.2.123. PMID: 217970Free PMC Article

Recent clinical studies

Etiology

Overview of the 2022 WHO Classification of Pituitary Tumors.
Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Silent pituitary plurihormonal adenoma: clinical relevance of immunohistochemical analysis.
García-Sáenz M, Uribe-Cortés D, González-Virla B, Mendoza-Zubieta V, Vargas-Ortega G
Rev Med Inst Mex Seguro Soc 2019 Apr 1;57(1):48-55. PMID: 31071255
VEGF, VEGF165b and EG-VEGF expression is specifically related with hormone profile in pituitary adenomas.
Corlan AS, Cîmpean AM, Melnic E, Raica M, Sarb S
Eur J Histochem 2019 Mar 5;63(1) doi: 10.4081/ejh.2019.3010. PMID: 30838843Free PMC Article
Clinical Implications of Accurate Subtyping of Pituitary Adenomas: Perspectives from the Treating Physician.
Gomez-Hernandez K, Ezzat S, Asa SL, Mete Ö
Turk Patoloji Derg 2015;31 Suppl 1:4-17. doi: 10.5146/tjpath.2015.01311. PMID: 26177314
Acromegaly: a review of 100 cases.
GORDON DA, HILL FM, EZRIN C
Can Med Assoc J 1962 Nov 24;87(21):1106-9. PMID: 13949186Free PMC Article

Diagnosis

Overview of the 2022 WHO Classification of Pituitary Tumors.
Asa SL, Mete O, Perry A, Osamura RY
Endocr Pathol 2022 Mar;33(1):6-26. Epub 2022 Mar 15 doi: 10.1007/s12022-022-09703-7. PMID: 35291028
Acidophil stem cell pituitary adenoma: a case report and literature review.
Annapurni A, Rathi M
Hormones (Athens) 2019 Dec;18(4):507-512. Epub 2019 Nov 13 doi: 10.1007/s42000-019-00154-0. PMID: 31721135
Clinical Implications of Accurate Subtyping of Pituitary Adenomas: Perspectives from the Treating Physician.
Gomez-Hernandez K, Ezzat S, Asa SL, Mete Ö
Turk Patoloji Derg 2015;31 Suppl 1:4-17. doi: 10.5146/tjpath.2015.01311. PMID: 26177314
Apoplexy accompanying pituitary adenoma as a complication of preoperative anterior pituitary function tests.
Yoshino A, Katayama Y, Watanabe T, Ogino A, Ohta T, Komine C, Yokoyama T, Fukushima T, Hirota H
Acta Neurochir (Wien) 2007 Jun;149(6):557-65; discussion 565. Epub 2007 Apr 30 doi: 10.1007/s00701-007-1155-8. PMID: 17468811
Acromegaly.
Ezzat S
Endocrinol Metab Clin North Am 1997 Dec;26(4):703-23. doi: 10.1016/s0889-8529(05)70278-4. PMID: 9429856

Therapy

Apoplexy accompanying pituitary adenoma as a complication of preoperative anterior pituitary function tests.
Yoshino A, Katayama Y, Watanabe T, Ogino A, Ohta T, Komine C, Yokoyama T, Fukushima T, Hirota H
Acta Neurochir (Wien) 2007 Jun;149(6):557-65; discussion 565. Epub 2007 Apr 30 doi: 10.1007/s00701-007-1155-8. PMID: 17468811
Pituitary surgery for the management of acromegaly.
Laws ER, Vance ML, Thapar K
Horm Res 2000;53 Suppl 3:71-5. doi: 10.1159/000023538. PMID: 10971109
New treatments for acromegaly.
Wass JA, Sheppard MC
J R Coll Physicians Lond 1998 Mar-Apr;32(2):113-7. PMID: 9597624Free PMC Article
"Aging bull'.
Geelhoed GW
Med Hypotheses 1996 Dec;47(6):471-9. doi: 10.1016/s0306-9877(96)90160-7. PMID: 8961245
Cyproheptadine-mediated inhibition of growth hormone and prolactin release from pituitary adenoma cells of acromegaly and gigantism in culture.
Ishibashi M, Fukushima T, Yamaji T
Acta Endocrinol (Copenh) 1985 Aug;109(4):474-80. doi: 10.1530/acta.0.1090474. PMID: 2994332

Prognosis

Silent pituitary plurihormonal adenoma: clinical relevance of immunohistochemical analysis.
García-Sáenz M, Uribe-Cortés D, González-Virla B, Mendoza-Zubieta V, Vargas-Ortega G
Rev Med Inst Mex Seguro Soc 2019 Apr 1;57(1):48-55. PMID: 31071255
VEGF, VEGF165b and EG-VEGF expression is specifically related with hormone profile in pituitary adenomas.
Corlan AS, Cîmpean AM, Melnic E, Raica M, Sarb S
Eur J Histochem 2019 Mar 5;63(1) doi: 10.4081/ejh.2019.3010. PMID: 30838843Free PMC Article
Epidemiology and biomarker profile of pituitary adenohypophysial tumors.
Mete O, Cintosun A, Pressman I, Asa SL
Mod Pathol 2018 Jun;31(6):900-909. Epub 2018 Feb 12 doi: 10.1038/s41379-018-0016-8. PMID: 29434339
Clinical Implications of Accurate Subtyping of Pituitary Adenomas: Perspectives from the Treating Physician.
Gomez-Hernandez K, Ezzat S, Asa SL, Mete Ö
Turk Patoloji Derg 2015;31 Suppl 1:4-17. doi: 10.5146/tjpath.2015.01311. PMID: 26177314
Morphogenesis and significance of fibrous bodies in human pituitary adenomas.
Horvath E, Kovacs K
Virchows Arch B Cell Pathol 1978 Mar 2;27(1):69-78. doi: 10.1007/BF02888984. PMID: 417457

Clinical prediction guides

Silent pituitary plurihormonal adenoma: clinical relevance of immunohistochemical analysis.
García-Sáenz M, Uribe-Cortés D, González-Virla B, Mendoza-Zubieta V, Vargas-Ortega G
Rev Med Inst Mex Seguro Soc 2019 Apr 1;57(1):48-55. PMID: 31071255
Epidemiology and biomarker profile of pituitary adenohypophysial tumors.
Mete O, Cintosun A, Pressman I, Asa SL
Mod Pathol 2018 Jun;31(6):900-909. Epub 2018 Feb 12 doi: 10.1038/s41379-018-0016-8. PMID: 29434339
Clinical Implications of Accurate Subtyping of Pituitary Adenomas: Perspectives from the Treating Physician.
Gomez-Hernandez K, Ezzat S, Asa SL, Mete Ö
Turk Patoloji Derg 2015;31 Suppl 1:4-17. doi: 10.5146/tjpath.2015.01311. PMID: 26177314
Apoplexy accompanying pituitary adenoma as a complication of preoperative anterior pituitary function tests.
Yoshino A, Katayama Y, Watanabe T, Ogino A, Ohta T, Komine C, Yokoyama T, Fukushima T, Hirota H
Acta Neurochir (Wien) 2007 Jun;149(6):557-65; discussion 565. Epub 2007 Apr 30 doi: 10.1007/s00701-007-1155-8. PMID: 17468811
Ectopic growth hormone-releasing adenoma in the cavernous sinus--case report.
Mitsuya K, Nakasu Y, Nioka H, Nakasu S
Neurol Med Chir (Tokyo) 2004 Jul;44(7):380-5. doi: 10.2176/nmc.44.380. PMID: 15347217

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...