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COVID-19 Dermatologic Manifestation

MedGen UID:
1754160
•Concept ID:
C5420366
•
Sign or Symptom
Synonym: COVID-19 Skin Manifestation

Definition

A skin abnormality that is associated with SARS-CoV-2 infection (COVID-19). [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCOVID-19 Dermatologic Manifestation

Professional guidelines

PubMed

Pathobiology of Cutaneous Manifestations Associated with COVID-19 and Their Management.
Masood W, Ahmad S, Khan NA, Shakir A, Rokni GR, Gold MH, Cockerell CJ, Schwartz RA, Goldust M
Viruses 2022 Sep 6;14(9) doi: 10.3390/v14091972. PMID: 36146777Free PMC Article
Differential Diagnosis of Lesions.
Milo RB
Adv Emerg Nurs J 2022 Jan-Mar 01;44(1):23-28. doi: 10.1097/TME.0000000000000388. PMID: 35089277
Identification, Mechanism, and Treatment of Skin Lesions in COVID-19: A Review.
Fernández-Lázaro D, Garrosa M
Viruses 2021 Sep 24;13(10) doi: 10.3390/v13101916. PMID: 34696346Free PMC Article

Recent clinical studies

Etiology

A systematic review on mucocutaneous presentations after COVID-19 vaccination and expert recommendations about vaccination of important immune-mediated dermatologic disorders.
Seirafianpour F, Pourriyahi H, Gholizadeh Mesgarha M, Pour Mohammad A, Shaka Z, Goodarzi A
Dermatol Ther 2022 Jun;35(6):e15461. Epub 2022 Apr 11 doi: 10.1111/dth.15461. PMID: 35316551Free PMC Article
COVID-19: The experience from Italy.
Recalcati S, Gianotti R, Fantini F
Clin Dermatol 2021 Jan-Feb;39(1):12-22. Epub 2020 Dec 17 doi: 10.1016/j.clindermatol.2020.12.008. PMID: 33972039Free PMC Article
Posterior Reversible Encephalopathy Syndrome.
Gewirtz AN, Gao V, Parauda SC, Robbins MS
Curr Pain Headache Rep 2021 Feb 25;25(3):19. doi: 10.1007/s11916-020-00932-1. PMID: 33630183Free PMC Article
Skin Manifestations Associated with COVID-19: Current Knowledge and Future Perspectives.
Genovese G, Moltrasio C, Berti E, Marzano AV
Dermatology 2021;237(1):1-12. Epub 2020 Nov 24 doi: 10.1159/000512932. PMID: 33232965Free PMC Article
Covid-19 pandemic and the skin.
Drenovska K, Schmidt E, Vassileva S
Int J Dermatol 2020 Nov;59(11):1312-1319. Epub 2020 Sep 21 doi: 10.1111/ijd.15189. PMID: 32954488Free PMC Article

Diagnosis

Scalp dysesthesia: a neuropathic phenomenon.
Ju T, Vander Does A, Yosipovitch G
J Eur Acad Dermatol Venereol 2022 Jun;36(6):790-796. Epub 2022 Feb 14 doi: 10.1111/jdv.17985. PMID: 35122352
COVID-19 Pediatric Dermatology.
Neale H, Hawryluk EB
Dermatol Clin 2021 Oct;39(4):505-519. Epub 2021 May 31 doi: 10.1016/j.det.2021.05.012. PMID: 34556241Free PMC Article
Posterior Reversible Encephalopathy Syndrome.
Gewirtz AN, Gao V, Parauda SC, Robbins MS
Curr Pain Headache Rep 2021 Feb 25;25(3):19. doi: 10.1007/s11916-020-00932-1. PMID: 33630183Free PMC Article
Dermatologic manifestations and complications of COVID-19.
Gottlieb M, Long B
Am J Emerg Med 2020 Sep;38(9):1715-1721. Epub 2020 Jun 6 doi: 10.1016/j.ajem.2020.06.011. PMID: 32731141Free PMC Article
Extrapulmonary manifestations of COVID-19.
Gupta A, Madhavan MV, Sehgal K, Nair N, Mahajan S, Sehrawat TS, Bikdeli B, Ahluwalia N, Ausiello JC, Wan EY, Freedberg DE, Kirtane AJ, Parikh SA, Maurer MS, Nordvig AS, Accili D, Bathon JM, Mohan S, Bauer KA, Leon MB, Krumholz HM, Uriel N, Mehra MR, Elkind MSV, Stone GW, Schwartz A, Ho DD, Bilezikian JP, Landry DW
Nat Med 2020 Jul;26(7):1017-1032. Epub 2020 Jul 10 doi: 10.1038/s41591-020-0968-3. PMID: 32651579

Therapy

Dermatopathology of COVID-19 infection and vaccination.
Fernández-Figueras MT
Pathologie (Heidelb) 2022 Aug;43(Suppl 1):114-118. Epub 2022 Oct 5 doi: 10.1007/s00292-022-01126-9. PMID: 36197514Free PMC Article
A systematic review on mucocutaneous presentations after COVID-19 vaccination and expert recommendations about vaccination of important immune-mediated dermatologic disorders.
Seirafianpour F, Pourriyahi H, Gholizadeh Mesgarha M, Pour Mohammad A, Shaka Z, Goodarzi A
Dermatol Ther 2022 Jun;35(6):e15461. Epub 2022 Apr 11 doi: 10.1111/dth.15461. PMID: 35316551Free PMC Article
Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of 414 cases.
McMahon DE, Amerson E, Rosenbach M, Lipoff JB, Moustafa D, Tyagi A, Desai SR, French LE, Lim HW, Thiers BH, Hruza GJ, Blumenthal KG, Fox LP, Freeman EE
J Am Acad Dermatol 2021 Jul;85(1):46-55. Epub 2021 Apr 7 doi: 10.1016/j.jaad.2021.03.092. PMID: 33838206Free PMC Article
COVID-19, microthromboses, inflammation, and platelet activating factor.
Demopoulos C, Antonopoulou S, Theoharides TC
Biofactors 2020 Nov;46(6):927-933. Epub 2020 Dec 9 doi: 10.1002/biof.1696. PMID: 33296106
COVID-19: An overview for dermatologists.
Sanghvi AR
Int J Dermatol 2020 Dec;59(12):1437-1449. Epub 2020 Oct 27 doi: 10.1111/ijd.15257. PMID: 33107038

Prognosis

Pediatric COVID toes and fingers.
Koschitzky M, Oyola RR, Lee-Wong M, Abittan B, Silverberg N
Clin Dermatol 2021 Jan-Feb;39(1):84-91. Epub 2021 Jan 14 doi: 10.1016/j.clindermatol.2020.12.016. PMID: 33972057Free PMC Article
COVID-19: The experience from Italy.
Recalcati S, Gianotti R, Fantini F
Clin Dermatol 2021 Jan-Feb;39(1):12-22. Epub 2020 Dec 17 doi: 10.1016/j.clindermatol.2020.12.008. PMID: 33972039Free PMC Article
Posterior Reversible Encephalopathy Syndrome.
Gewirtz AN, Gao V, Parauda SC, Robbins MS
Curr Pain Headache Rep 2021 Feb 25;25(3):19. doi: 10.1007/s11916-020-00932-1. PMID: 33630183Free PMC Article
Covid-19 pandemic and the skin.
Drenovska K, Schmidt E, Vassileva S
Int J Dermatol 2020 Nov;59(11):1312-1319. Epub 2020 Sep 21 doi: 10.1111/ijd.15189. PMID: 32954488Free PMC Article
Dermatologic manifestations and complications of COVID-19.
Gottlieb M, Long B
Am J Emerg Med 2020 Sep;38(9):1715-1721. Epub 2020 Jun 6 doi: 10.1016/j.ajem.2020.06.011. PMID: 32731141Free PMC Article

Clinical prediction guides

Levamisole-induced and COVID-19-induced retiform purpura: two overlapping, emerging clinical syndromes.
Keim CK, Schwartz RA, Kapila R
Arch Dermatol Res 2023 Mar;315(2):265-273. Epub 2021 Nov 22 doi: 10.1007/s00403-021-02303-1. PMID: 34807290Free PMC Article
Pathobiology of Cutaneous Manifestations Associated with COVID-19 and Their Management.
Masood W, Ahmad S, Khan NA, Shakir A, Rokni GR, Gold MH, Cockerell CJ, Schwartz RA, Goldust M
Viruses 2022 Sep 6;14(9) doi: 10.3390/v14091972. PMID: 36146777Free PMC Article
A systematic review on mucocutaneous presentations after COVID-19 vaccination and expert recommendations about vaccination of important immune-mediated dermatologic disorders.
Seirafianpour F, Pourriyahi H, Gholizadeh Mesgarha M, Pour Mohammad A, Shaka Z, Goodarzi A
Dermatol Ther 2022 Jun;35(6):e15461. Epub 2022 Apr 11 doi: 10.1111/dth.15461. PMID: 35316551Free PMC Article
COVID-19: The experience from Italy.
Recalcati S, Gianotti R, Fantini F
Clin Dermatol 2021 Jan-Feb;39(1):12-22. Epub 2020 Dec 17 doi: 10.1016/j.clindermatol.2020.12.008. PMID: 33972039Free PMC Article
Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of 414 cases.
McMahon DE, Amerson E, Rosenbach M, Lipoff JB, Moustafa D, Tyagi A, Desai SR, French LE, Lim HW, Thiers BH, Hruza GJ, Blumenthal KG, Fox LP, Freeman EE
J Am Acad Dermatol 2021 Jul;85(1):46-55. Epub 2021 Apr 7 doi: 10.1016/j.jaad.2021.03.092. PMID: 33838206Free PMC Article

Recent systematic reviews

Cutaneous adverse reactions following COVID-19 vaccinations: A systematic review and meta-analysis.
Shafie'ei M, Jamali M, Akbari Z, Sarvipour N, Ahmadzade M, Ahramiyanpour N
J Cosmet Dermatol 2022 Sep;21(9):3636-3650. Epub 2022 Aug 1 doi: 10.1111/jocd.15261. PMID: 35861631Free PMC Article
A systematic review on mucocutaneous presentations after COVID-19 vaccination and expert recommendations about vaccination of important immune-mediated dermatologic disorders.
Seirafianpour F, Pourriyahi H, Gholizadeh Mesgarha M, Pour Mohammad A, Shaka Z, Goodarzi A
Dermatol Ther 2022 Jun;35(6):e15461. Epub 2022 Apr 11 doi: 10.1111/dth.15461. PMID: 35316551Free PMC Article
Severe and life-threatening COVID-19-related mucocutaneous eruptions: A systematic review.
Mashayekhi F, Seirafianpour F, Pour Mohammad A, Goodarzi A
Int J Clin Pract 2021 Dec;75(12):e14720. Epub 2021 Sep 28 doi: 10.1111/ijcp.14720. PMID: 34411409Free PMC Article
Pediatric COVID toes and fingers.
Koschitzky M, Oyola RR, Lee-Wong M, Abittan B, Silverberg N
Clin Dermatol 2021 Jan-Feb;39(1):84-91. Epub 2021 Jan 14 doi: 10.1016/j.clindermatol.2020.12.016. PMID: 33972057Free PMC Article
Dermatologic manifestations of COVID-19: a comprehensive systematic review.
Mirza FN, Malik AA, Omer SB, Sethi A
Int J Dermatol 2021 Apr;60(4):418-450. Epub 2020 Nov 3 doi: 10.1111/ijd.15168. PMID: 33141443

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