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Appendix Mucinous Neoplasm

MedGen UID:
1763797
•Concept ID:
C5418760
•
Neoplastic Process
Synonym: Appendix Mucinous Tumor

Definition

An appendiceal neoplasm characterized by mucinous epithelial proliferation with extracellular mucin and pushing tumour margins. (WHO 2019) [from NCI]

Professional guidelines

PubMed

Appendiceal tumours and pseudomyxoma peritonei: Literature review with PSOGI/EURACAN clinical practice guidelines for diagnosis and treatment.
Govaerts K, Lurvink RJ, De Hingh IHJT, Van der Speeten K, Villeneuve L, Kusamura S, Kepenekian V, Deraco M, Glehen O, Moran BJ; PSOGI
Eur J Surg Oncol 2021 Jan;47(1):11-35. Epub 2020 Feb 28 doi: 10.1016/j.ejso.2020.02.012. PMID: 32199769
The histopathological classification, diagnosis and differential diagnosis of mucinous appendiceal neoplasms, appendiceal adenocarcinomas and pseudomyxoma peritonei.
Carr NJ, Bibeau F, Bradley RF, Dartigues P, Feakins RM, Geisinger KR, Gui X, Isaac S, Milione M, Misdraji J, Pai RK, Rodriguez-Justo M, Sobin LH, van Velthuysen MF, Yantiss RK
Histopathology 2017 Dec;71(6):847-858. Epub 2017 Sep 19 doi: 10.1111/his.13324. PMID: 28746986
Appendiceal Mucinous Neoplasms: Diagnosis and Management.
Shaib WL, Assi R, Shamseddine A, Alese OB, Staley C 3rd, Memis B, Adsay V, Bekaii-Saab T, El-Rayes BF
Oncologist 2017 Sep;22(9):1107-1116. Epub 2017 Jun 29 doi: 10.1634/theoncologist.2017-0081. PMID: 28663356Free PMC Article

Recent clinical studies

Diagnosis

The appendix "mucocoele" misnomer: radiological terminology of "likely appendix mucinous neoplasm" better reflects pathology findings.
Bhagwanani A, El-Sheikha J, Shah N, Thrower A, Carr NJ, Moran BJ
Clin Radiol 2023 Mar;78(3):234-238. Epub 2022 Nov 18 doi: 10.1016/j.crad.2022.10.005. PMID: 36411089

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