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Unresectable Distal Esophagus Adenocarcinoma

MedGen UID:
1769328
•Concept ID:
C5419540
•
Neoplastic Process

Definition

Distal esophagus adenocarcinoma that is not amenable to surgical resection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVUnresectable Distal Esophagus Adenocarcinoma

Recent clinical studies

Etiology

The role of staging laparoscopy in oesophagogastric cancers.
de Graaf GW, Ayantunde AA, Parsons SL, Duffy JP, Welch NT
Eur J Surg Oncol 2007 Oct;33(8):988-92. Epub 2007 Mar 7 doi: 10.1016/j.ejso.2007.01.007. PMID: 17344017
Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127.
Dragovich T, McCoy S, Fenoglio-Preiser CM, Wang J, Benedetti JK, Baker AF, Hackett CB, Urba SG, Zaner KS, Blanke CD, Abbruzzese JL
J Clin Oncol 2006 Oct 20;24(30):4922-7. doi: 10.1200/JCO.2006.07.1316. PMID: 17050876
Targeted therapies for esophageal cancer.
Tew WP, Kelsen DP, Ilson DH
Oncologist 2005 Sep;10(8):590-601. doi: 10.1634/theoncologist.10-8-590. PMID: 16177283
Adenocarcinoma of distal esophagus and gastroesophageal junction: long-term results of surgical treatment in a North Indian Center.
Parshad R, Singh RK, Kumar A, Gupta SD, Chattopadhyay TK
World J Surg 1999 Mar;23(3):277-83. doi: 10.1007/pl00013179. PMID: 9933700
Neo-adjuvant chemotherapy with carboplatin, 4-epiadriamycin and teniposide (CET) in locally advanced cancer of the cardia and the lower oesophagus: a phase II study.
Plukker JT, Sleijfer DT, Verschueren RC, Van der Graaf WT, Mulder NH
Anticancer Res 1995 Sep-Oct;15(5B):2357-61. PMID: 8572652

Diagnosis

The role of staging laparoscopy in oesophagogastric cancers.
de Graaf GW, Ayantunde AA, Parsons SL, Duffy JP, Welch NT
Eur J Surg Oncol 2007 Oct;33(8):988-92. Epub 2007 Mar 7 doi: 10.1016/j.ejso.2007.01.007. PMID: 17344017
Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127.
Dragovich T, McCoy S, Fenoglio-Preiser CM, Wang J, Benedetti JK, Baker AF, Hackett CB, Urba SG, Zaner KS, Blanke CD, Abbruzzese JL
J Clin Oncol 2006 Oct 20;24(30):4922-7. doi: 10.1200/JCO.2006.07.1316. PMID: 17050876
Targeted therapies for esophageal cancer.
Tew WP, Kelsen DP, Ilson DH
Oncologist 2005 Sep;10(8):590-601. doi: 10.1634/theoncologist.10-8-590. PMID: 16177283

Therapy

Radiotherapy for Esophageal Adenocarcinoma.
Kwong DLW, Lam KO
Methods Mol Biol 2018;1756:7-17. doi: 10.1007/978-1-4939-7734-5_2. PMID: 29600356
Individualization of metal stents for management of gastric outlet obstruction caused by distal stomach cancer: a prospective study.
Shi D, Bao YS, Liu YP
Gastrointest Endosc 2013 Aug;78(2):277-84. Epub 2013 Mar 23 doi: 10.1016/j.gie.2013.02.007. PMID: 23528652
Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127.
Dragovich T, McCoy S, Fenoglio-Preiser CM, Wang J, Benedetti JK, Baker AF, Hackett CB, Urba SG, Zaner KS, Blanke CD, Abbruzzese JL
J Clin Oncol 2006 Oct 20;24(30):4922-7. doi: 10.1200/JCO.2006.07.1316. PMID: 17050876
Targeted therapies for esophageal cancer.
Tew WP, Kelsen DP, Ilson DH
Oncologist 2005 Sep;10(8):590-601. doi: 10.1634/theoncologist.10-8-590. PMID: 16177283
Neo-adjuvant chemotherapy with carboplatin, 4-epiadriamycin and teniposide (CET) in locally advanced cancer of the cardia and the lower oesophagus: a phase II study.
Plukker JT, Sleijfer DT, Verschueren RC, Van der Graaf WT, Mulder NH
Anticancer Res 1995 Sep-Oct;15(5B):2357-61. PMID: 8572652

Prognosis

Surgical palliation for Barrett's esophagus cancer.
Qureshi I, Shende M, Luketich JD
Surg Oncol Clin N Am 2009 Jul;18(3):547-60. doi: 10.1016/j.soc.2009.03.009. PMID: 19500743
Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127.
Dragovich T, McCoy S, Fenoglio-Preiser CM, Wang J, Benedetti JK, Baker AF, Hackett CB, Urba SG, Zaner KS, Blanke CD, Abbruzzese JL
J Clin Oncol 2006 Oct 20;24(30):4922-7. doi: 10.1200/JCO.2006.07.1316. PMID: 17050876
Targeted therapies for esophageal cancer.
Tew WP, Kelsen DP, Ilson DH
Oncologist 2005 Sep;10(8):590-601. doi: 10.1634/theoncologist.10-8-590. PMID: 16177283
Endoscopic cryotherapy: experimental results and first clinical use.
Pasricha PJ, Hill S, Wadwa KS, Gislason GT, Okolo PI 3rd, Magee CA, Canto MI, Kuo WH, Baust JG, Kalloo AN
Gastrointest Endosc 1999 May;49(5):627-31. doi: 10.1016/s0016-5107(99)70393-7. PMID: 10228263
Adenocarcinoma of distal esophagus and gastroesophageal junction: long-term results of surgical treatment in a North Indian Center.
Parshad R, Singh RK, Kumar A, Gupta SD, Chattopadhyay TK
World J Surg 1999 Mar;23(3):277-83. doi: 10.1007/pl00013179. PMID: 9933700

Clinical prediction guides

Individualization of metal stents for management of gastric outlet obstruction caused by distal stomach cancer: a prospective study.
Shi D, Bao YS, Liu YP
Gastrointest Endosc 2013 Aug;78(2):277-84. Epub 2013 Mar 23 doi: 10.1016/j.gie.2013.02.007. PMID: 23528652
The role of staging laparoscopy in oesophagogastric cancers.
de Graaf GW, Ayantunde AA, Parsons SL, Duffy JP, Welch NT
Eur J Surg Oncol 2007 Oct;33(8):988-92. Epub 2007 Mar 7 doi: 10.1016/j.ejso.2007.01.007. PMID: 17344017
Phase II trial of erlotinib in gastroesophageal junction and gastric adenocarcinomas: SWOG 0127.
Dragovich T, McCoy S, Fenoglio-Preiser CM, Wang J, Benedetti JK, Baker AF, Hackett CB, Urba SG, Zaner KS, Blanke CD, Abbruzzese JL
J Clin Oncol 2006 Oct 20;24(30):4922-7. doi: 10.1200/JCO.2006.07.1316. PMID: 17050876
Adenocarcinoma of distal esophagus and gastroesophageal junction: long-term results of surgical treatment in a North Indian Center.
Parshad R, Singh RK, Kumar A, Gupta SD, Chattopadhyay TK
World J Surg 1999 Mar;23(3):277-83. doi: 10.1007/pl00013179. PMID: 9933700

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