U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Skin Spindle Cell/Pleomorphic Lipoma

MedGen UID:
1773770
•Concept ID:
C5418576
•
Neoplastic Process

Definition

A spindle cell/pleomorphic lipoma arising from the skin. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSkin Spindle Cell/Pleomorphic Lipoma

Recent clinical studies

Etiology

Histopathologic and genetic findings in atypical spindle cell/pleomorphic lipomatous tumors and atypical pleomorphic fibromas.
Kouhsari LM, LeBoit PE, McCalmont TH, Hinds B, North JP
J Cutan Pathol 2022 Jul;49(7):623-631. Epub 2022 Apr 5 doi: 10.1111/cup.14230. PMID: 35332938
CD34-positive superficial myxofibrosarcoma: a potential diagnostic pitfall.
Smith SC, Poznanski AA, Fullen DR, Ma L, McHugh JB, Lucas DR, Patel RM
J Cutan Pathol 2013 Jul;40(7):639-45. Epub 2013 Apr 19 doi: 10.1111/cup.12158. PMID: 23600956
Intradermal spindle cell/pleomorphic lipoma: a distinct subset.
French CA, Mentzel T, Kutzner H, Fletcher CD
Am J Dermatopathol 2000 Dec;22(6):496-502. doi: 10.1097/00000372-200012000-00003. PMID: 11190440
Atypical subcutaneous fatty tumors: a review of 37 referred cases.
Allen PW, Strungs I, MacCormac LB
Pathology 1998 May;30(2):123-35. doi: 10.1080/00313029800169066. PMID: 9643489

Diagnosis

Spindle Cell/Pleomorphic Lipoma With Trichodiscoma-like Epithelial Hyperplasia Mimicking Atypical Fibroxanthoma/Pleomorphic Dermal Sarcoma.
Aghighi M, Andea AA, Patel RM, Fullen DR, Bresler SC
Am J Dermatopathol 2022 Oct 1;44(10):764-767. Epub 2022 Apr 27 doi: 10.1097/DAD.0000000000002206. PMID: 35503875
Histopathologic and genetic findings in atypical spindle cell/pleomorphic lipomatous tumors and atypical pleomorphic fibromas.
Kouhsari LM, LeBoit PE, McCalmont TH, Hinds B, North JP
J Cutan Pathol 2022 Jul;49(7):623-631. Epub 2022 Apr 5 doi: 10.1111/cup.14230. PMID: 35332938
Uncommon Tumor, Uncommon Location: A Dermal-Based Spindle Cell/Pleomorphic Lipoma.
Lincoln M, Royer M
Am J Dermatopathol 2016 Aug;38(8):e122-4. doi: 10.1097/DAD.0000000000000546. PMID: 26913848
Intradermal spindle cell/pleomorphic lipoma of the vulva: case report and review of the literature.
Reis-Filho JS, Milanezi F, Soares MF, Fillus-Neto J, Schmitt FC
J Cutan Pathol 2002 Jan;29(1):59-62. doi: 10.1034/j.1600-0560.2002.290112.x. PMID: 11841521
Intradermal spindle cell/pleomorphic lipoma: a distinct subset.
French CA, Mentzel T, Kutzner H, Fletcher CD
Am J Dermatopathol 2000 Dec;22(6):496-502. doi: 10.1097/00000372-200012000-00003. PMID: 11190440

Therapy

CD34-positive superficial myxofibrosarcoma: a potential diagnostic pitfall.
Smith SC, Poznanski AA, Fullen DR, Ma L, McHugh JB, Lucas DR, Patel RM
J Cutan Pathol 2013 Jul;40(7):639-45. Epub 2013 Apr 19 doi: 10.1111/cup.12158. PMID: 23600956
Selected case from the Arkadi M. Rywlin International Pathology Slide Seminar: sclerotic (fibroma-like) lipoma, dorsum of right hand.
Allen PW
Adv Anat Pathol 2013 Jan;20(1):68-72. doi: 10.1097/PAP.0b013e31827b65e3. PMID: 23232574
Sclerotic (fibroma-like) lipoma: a distinctive lipoma variant with a predilection for the distal extremities.
Laskin WB, Fetsch JF, Michal M, Miettinen M
Am J Dermatopathol 2006 Aug;28(4):308-16. doi: 10.1097/00000372-200608000-00003. PMID: 16871033

Prognosis

Uncommon Tumor, Uncommon Location: A Dermal-Based Spindle Cell/Pleomorphic Lipoma.
Lincoln M, Royer M
Am J Dermatopathol 2016 Aug;38(8):e122-4. doi: 10.1097/DAD.0000000000000546. PMID: 26913848
Cutaneous lipomatous neoplasms.
Mentzel T
Semin Diagn Pathol 2001 Nov;18(4):250-7. PMID: 11757864

Clinical prediction guides

Histopathologic and genetic findings in atypical spindle cell/pleomorphic lipomatous tumors and atypical pleomorphic fibromas.
Kouhsari LM, LeBoit PE, McCalmont TH, Hinds B, North JP
J Cutan Pathol 2022 Jul;49(7):623-631. Epub 2022 Apr 5 doi: 10.1111/cup.14230. PMID: 35332938
Uncommon Tumor, Uncommon Location: A Dermal-Based Spindle Cell/Pleomorphic Lipoma.
Lincoln M, Royer M
Am J Dermatopathol 2016 Aug;38(8):e122-4. doi: 10.1097/DAD.0000000000000546. PMID: 26913848

Supplemental Content

Table of contents

    Related information

    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...