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Mixed lobular and ductal breast carcinoma

MedGen UID:
1779609
•Concept ID:
C5441546
•
Neoplastic Process
Synonyms: Breast Mixed Ductal and Lobular Carcinoma; breast mixed ductal and lobular carcinoma; Carcinoma of breast with ductal and lobular features; Ductal and Lobular Carcinoma; ductal and lobular carcinoma; Mixed Ductal and Lobular Breast Carcinoma; mixed ductal and lobular breast carcinoma; Mixed Ductal and Lobular Carcinoma; Mixed ductal and lobular carcinoma of breast; Mixed Ductal and Lobular Carcinoma of Breast; mixed ductal and lobular carcinoma of breast; Mixed Ductal and Lobular Carcinoma of the Breast; mixed ductal and lobular carcinoma of the breast; Mixed Lobular and Ductal Breast Carcinoma; mixed lobular and ductal breast carcinoma; Mixed Lobular and Ductal Carcinoma; mixed lobular and ductal carcinoma; Mixed Lobular and Ductal Carcinoma of Breast; mixed lobular and ductal carcinoma of breast; Mixed Lobular and Ductal Carcinoma of the Breast; mixed lobular and ductal carcinoma of the breast
SNOMED CT: Carcinoma of breast with ductal and lobular features (444604002); Mixed ductal and lobular carcinoma of breast (444604002)
 
Monarch Initiative: MONDO:0006306

Definition

A breast carcinoma characterized by the presence of a lobular and a ductal component. The ductal component comprises less than 50 percent of the tumor. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMixed lobular and ductal breast carcinoma

Professional guidelines

PubMed

Detection Rates for Benign and Malignant Diagnoses on Breast Cancer Screening With Digital Breast Tomosynthesis in a Statewide Mammography Registry Study.
Fujii MH, Herschorn SD, Sowden M, Hotaling EL, Vacek PM, Weaver DL, Sprague BL
AJR Am J Roentgenol 2019 Mar;212(3):706-711. Epub 2019 Jan 23 doi: 10.2214/AJR.18.20255. PMID: 30673339Free PMC Article
Management of in situ lobular neoplasia detected on needle core biopsy of breast.
Purdie CA, McLean D, Stormonth E, Macaskill EJ, McCullough JB, Edwards SL, Brown DC, Jordan LB
J Clin Pathol 2010 Nov;63(11):987-93. doi: 10.1136/jcp.2010.081687. PMID: 20972243
Increased incidence of lobular breast cancer in women treated with hormone replacement therapy: implications for diagnosis, surgical and medical treatment.
Biglia N, Mariani L, Sgro L, Mininanni P, Moggio G, Sismondi P
Endocr Relat Cancer 2007 Sep;14(3):549-67. doi: 10.1677/ERC-06-0060. PMID: 17914088

Recent clinical studies

Etiology

Relation of regimens of combined hormone replacement therapy to lobular, ductal, and other histologic types of breast carcinoma.
Daling JR, Malone KE, Doody DR, Voigt LF, Bernstein L, Coates RJ, Marchbanks PA, Norman SA, Weiss LK, Ursin G, Berlin JA, Burkman RT, Deapen D, Folger SG, McDonald JA, Simon MS, Strom BL, Wingo PA, Spirtas R
Cancer 2002 Dec 15;95(12):2455-64. doi: 10.1002/cncr.10984. PMID: 12467057

Diagnosis

Relation of regimens of combined hormone replacement therapy to lobular, ductal, and other histologic types of breast carcinoma.
Daling JR, Malone KE, Doody DR, Voigt LF, Bernstein L, Coates RJ, Marchbanks PA, Norman SA, Weiss LK, Ursin G, Berlin JA, Burkman RT, Deapen D, Folger SG, McDonald JA, Simon MS, Strom BL, Wingo PA, Spirtas R
Cancer 2002 Dec 15;95(12):2455-64. doi: 10.1002/cncr.10984. PMID: 12467057

Therapy

Relation of regimens of combined hormone replacement therapy to lobular, ductal, and other histologic types of breast carcinoma.
Daling JR, Malone KE, Doody DR, Voigt LF, Bernstein L, Coates RJ, Marchbanks PA, Norman SA, Weiss LK, Ursin G, Berlin JA, Burkman RT, Deapen D, Folger SG, McDonald JA, Simon MS, Strom BL, Wingo PA, Spirtas R
Cancer 2002 Dec 15;95(12):2455-64. doi: 10.1002/cncr.10984. PMID: 12467057

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