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Posttraumatic stress symptom

MedGen UID:
1787308
Concept ID:
C5539757
Mental or Behavioral Dysfunction
Synonym: PTSD
 
HPO: HP:0033676

Definition

A behavioral or psychological symptom that typically occurs following exposure to one or more traumatic events is posttraumatic stress disorder (PTSD). Symptoms of PTSD include intrusive recollections, such as re-experiencing the trauma through flashbacks, memories, or nightmares. Additionally, individuals may experience avoidant and numbing symptoms, which can include diminished emotions and avoidance of situations that serve as reminders of the traumatic event. Hyperarousal is another symptom, characterized by increased irritability, exaggerated startle reactions, and difficulties with sleeping or concentrating. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPosttraumatic stress symptom

Professional guidelines

PubMed

Lakin DP, Win KS, Aung H, Soe KNC, Kyi B, Marcell AV, Tol WA, Bass JK
BMC Public Health 2021 Jan 25;21(1):211. doi: 10.1186/s12889-021-10249-2. PMID: 33494730Free PMC Article
Garey L, Bakhshaie J, Vujanovic AA, Reitzel LR, Schmidt NB, Zvolensky MJ
Addict Behav 2016 Sep;60:84-9. Epub 2016 Apr 2 doi: 10.1016/j.addbeh.2016.03.038. PMID: 27100473Free PMC Article
Sabin JA, Zatzick DF, Jurkovich G, Rivara FP
Pediatrics 2006 Jan;117(1):130-8. doi: 10.1542/peds.2005-1042. PMID: 16396870

Recent clinical studies

Etiology

Wendlandt B, Pongracz L, Lin FC, Toles M, Gaynes BN, Hanson LC, Carson SS
JAMA Netw Open 2023 Apr 3;6(4):e237448. doi: 10.1001/jamanetworkopen.2023.7448. PMID: 37027154Free PMC Article
Howe ES, Fisher AJ
J Trauma Stress 2022 Oct;35(5):1508-1520. Epub 2022 Jul 21 doi: 10.1002/jts.22857. PMID: 35864591
Owens GP, Hamrick LA, Keller EM, Perkins M, Collins S, Thomas EA, Haag I, Swan S, Pickering N
J Clin Psychol 2022 Dec;78(12):2564-2578. Epub 2022 May 4 doi: 10.1002/jclp.23369. PMID: 35510293
Thomas JL, Cleveland S, Pietrzak RH, Dunkel Schetter C, Sumner JA
J Affect Disord 2021 Nov 1;294:314-321. Epub 2021 Jul 18 doi: 10.1016/j.jad.2021.07.025. PMID: 34311331Free PMC Article
Lai BS, Lewis R, Livings MS, La Greca AM, Esnard AM
J Trauma Stress 2017 Dec;30(6):571-582. Epub 2017 Nov 28 doi: 10.1002/jts.22242. PMID: 29193316Free PMC Article

Diagnosis

Howe ES, Fisher AJ
J Trauma Stress 2022 Oct;35(5):1508-1520. Epub 2022 Jul 21 doi: 10.1002/jts.22857. PMID: 35864591
Morris MC, Sanchez-Sáez F, Bailey B, Hellman N, Williams A, Schumacher JA, Rao U
J Interpers Violence 2022 Jul;37(13-14):NP11460-NP11489. Epub 2020 Nov 30 doi: 10.1177/0886260520978195. PMID: 33256508Free PMC Article
Thomas JL, Cleveland S, Pietrzak RH, Dunkel Schetter C, Sumner JA
J Affect Disord 2021 Nov 1;294:314-321. Epub 2021 Jul 18 doi: 10.1016/j.jad.2021.07.025. PMID: 34311331Free PMC Article
Franz CE, Hatton SN, Hauger RL, Kredlow MA, Dale AM, Eyler L, McEvoy LK, Fennema-Notestine C, Hagler D Jr, Jacobson KC, McKenzie RE, Panizzon MS, Gustavson DE, Xian H, Toomey R, Beck A, Stevens S, Tu X, Lyons MJ, Kremen WS
Brain Imaging Behav 2020 Aug;14(4):1208-1220. doi: 10.1007/s11682-019-00059-x. PMID: 30830577Free PMC Article
Thompson EJ, Anderson VA, Hearps SJC, McCarthy MC, Mihalopoulos C, Nicholson JM, Rayner M, Muscara F
Health Psychol 2017 Aug;36(8):779-786. Epub 2017 May 22 doi: 10.1037/hea0000476. PMID: 28530432

Therapy

Marx BP, Fina BA, Sloan DM, Young-McCaughan S, Dondanville KA, Tyler HC, Blankenship AE, Schrader CC, Kaplan AM, Green VR, Bryan CJ, Hale WJ, Mintz J, Peterson AL; STRONG STAR Consortium
Contemp Clin Trials 2021 Nov;110:106564. Epub 2021 Sep 5 doi: 10.1016/j.cct.2021.106564. PMID: 34496277
Dawson RL, Calear AL, McCallum SM, McKenna S, Nixon RDV, O'Kearney R
J Trauma Stress 2021 Feb;34(1):81-91. Epub 2020 Oct 11 doi: 10.1002/jts.22596. PMID: 33043507
Zvolensky MJ, Rogers AH, Shepherd JM, Vujanovic AA, Bakhshaie J
J Behav Med 2020 Apr;43(2):174-184. Epub 2020 Feb 18 doi: 10.1007/s10865-020-00142-5. PMID: 32072365
Gruebner O, Lowe SR, Tracy M, Joshi S, Cerdá M, Norris FH, Subramanian SV, Galea S
Sci Rep 2016 Aug 25;6:32242. doi: 10.1038/srep32242. PMID: 27558011Free PMC Article
Zandberg LJ, Rosenfield D, McLean CP, Powers MB, Asnaani A, Foa EB
J Consult Clin Psychol 2016 Jan;84(1):43-56. Epub 2015 Oct 12 doi: 10.1037/ccp0000052. PMID: 26460570Free PMC Article

Prognosis

Howe ES, Fisher AJ
J Trauma Stress 2022 Oct;35(5):1508-1520. Epub 2022 Jul 21 doi: 10.1002/jts.22857. PMID: 35864591
Owens GP, Hamrick LA, Keller EM, Perkins M, Collins S, Thomas EA, Haag I, Swan S, Pickering N
J Clin Psychol 2022 Dec;78(12):2564-2578. Epub 2022 May 4 doi: 10.1002/jclp.23369. PMID: 35510293
Morris MC, Sanchez-Sáez F, Bailey B, Hellman N, Williams A, Schumacher JA, Rao U
J Interpers Violence 2022 Jul;37(13-14):NP11460-NP11489. Epub 2020 Nov 30 doi: 10.1177/0886260520978195. PMID: 33256508Free PMC Article
Franz CE, Hatton SN, Hauger RL, Kredlow MA, Dale AM, Eyler L, McEvoy LK, Fennema-Notestine C, Hagler D Jr, Jacobson KC, McKenzie RE, Panizzon MS, Gustavson DE, Xian H, Toomey R, Beck A, Stevens S, Tu X, Lyons MJ, Kremen WS
Brain Imaging Behav 2020 Aug;14(4):1208-1220. doi: 10.1007/s11682-019-00059-x. PMID: 30830577Free PMC Article
Lai BS, Lewis R, Livings MS, La Greca AM, Esnard AM
J Trauma Stress 2017 Dec;30(6):571-582. Epub 2017 Nov 28 doi: 10.1002/jts.22242. PMID: 29193316Free PMC Article

Clinical prediction guides

Wendlandt B, Pongracz L, Lin FC, Toles M, Gaynes BN, Hanson LC, Carson SS
JAMA Netw Open 2023 Apr 3;6(4):e237448. doi: 10.1001/jamanetworkopen.2023.7448. PMID: 37027154Free PMC Article
Howe ES, Fisher AJ
J Trauma Stress 2022 Oct;35(5):1508-1520. Epub 2022 Jul 21 doi: 10.1002/jts.22857. PMID: 35864591
Owens GP, Hamrick LA, Keller EM, Perkins M, Collins S, Thomas EA, Haag I, Swan S, Pickering N
J Clin Psychol 2022 Dec;78(12):2564-2578. Epub 2022 May 4 doi: 10.1002/jclp.23369. PMID: 35510293
Morris MC, Sanchez-Sáez F, Bailey B, Hellman N, Williams A, Schumacher JA, Rao U
J Interpers Violence 2022 Jul;37(13-14):NP11460-NP11489. Epub 2020 Nov 30 doi: 10.1177/0886260520978195. PMID: 33256508Free PMC Article
Lai BS, Lewis R, Livings MS, La Greca AM, Esnard AM
J Trauma Stress 2017 Dec;30(6):571-582. Epub 2017 Nov 28 doi: 10.1002/jts.22242. PMID: 29193316Free PMC Article

Recent systematic reviews

Dawson RL, Calear AL, McCallum SM, McKenna S, Nixon RDV, O'Kearney R
J Trauma Stress 2021 Feb;34(1):81-91. Epub 2020 Oct 11 doi: 10.1002/jts.22596. PMID: 33043507

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