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Abnormal pulmonary alveolar system development

MedGen UID:: 1787462
•Concept ID:: C5539891
•: Anatomical Abnormality

HPO:	HP:4000060

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVAbnormal pulmonary alveolar system development

Phenotypic abnormality
- Abnormality of the respiratory system
  - Abnormal respiratory system physiology
    - Abnormal respiratory system morphology
      - Abnormality of the lung
        Abnormal lung development
        Abnormal pulmonary alveolar system development
        Alveolar capillary dysplasia
        Polyalveolar lobe

Professional guidelines

PubMed

Practice parameters for the respiratory indications for polysomnography in children.

Aurora RN, Zak RS, Karippot A, Lamm CI, Morgenthaler TI, Auerbach SH, Bista SR, Casey KR, Chowdhuri S, Kristo DA, Ramar K; American Academy of Sleep Medicine
Sleep 2011 Mar 1;34(3):379-88. doi: 10.1093/sleep/34.3.379. PMID: 21359087 Free PMC Article

Sleep-wake cycles and the management of respiratory failure.

Olson EJ, Simon PM
Curr Opin Pulm Med 1996 Nov;2(6):500-6. PMID: 9363192

Congenital central hypoventilation syndrome: diagnosis, management, and long-term outcome in thirty-two children.

Weese-Mayer DE, Silvestri JM, Menzies LJ, Morrow-Kenny AS, Hunt CE, Hauptman SA
J Pediatr 1992 Mar;120(3):381-7. doi: 10.1016/s0022-3476(05)80901-1. PMID: 1538284

See all (3)

Recent clinical studies

Etiology

Conditional knockout of ITGB4 in bronchial epithelial cells directs bronchopulmonary dysplasia.

Chen Y, Jiang W, Wang JM, Ma XD, Wu D, Liu LX, Ji M, Qu XP, Liu C, Liu HJ, Qin XQ, Xiang Y
J Cell Mol Med 2023 Dec;27(23):3760-3772. Epub 2023 Sep 12 doi: 10.1111/jcmm.17948. PMID: 37698050 Free PMC Article

Cardiovascular impact and sequelae of bronchopulmonary dysplasia.

Yallapragada SG, Savani RC, Goss KN
Pediatr Pulmonol 2021 Nov;56(11):3453-3463. Epub 2021 Mar 23 doi: 10.1002/ppul.25370. PMID: 33756045

Leptospirosis in humans.

Haake DA, Levett PN
Curr Top Microbiol Immunol 2015;387:65-97. doi: 10.1007/978-3-662-45059-8_5. PMID: 25388133 Free PMC Article

Pulmonary vascular development goes awry in congenital lung abnormalities.

Kool H, Mous D, Tibboel D, de Klein A, Rottier RJ
Birth Defects Res C Embryo Today 2014 Dec;102(4):343-58. Epub 2014 Nov 26 doi: 10.1002/bdrc.21085. PMID: 25424472

Acute respiratory distress syndrome.

Monahan LJ
Curr Probl Pediatr Adolesc Health Care 2013 Nov-Dec;43(10):278-84. doi: 10.1016/j.cppeds.2013.10.004. PMID: 24295609

See all (29)

Diagnosis

E-cigarette or vaping product use-associated lung injury: A review of clinico-radio-pathological characteristics.

Garg I, Vidholia A, Garg A, Singh S, Agahi A, Laroia A, Saboo SS, Comellas AP, Hoffman EA, Nagpal P
Respir Investig 2022 Nov;60(6):738-749. Epub 2022 Aug 11 doi: 10.1016/j.resinv.2022.06.011. PMID: 35963780

Nanoparticle Delivery of STAT3 Alleviates Pulmonary Hypertension in a Mouse Model of Alveolar Capillary Dysplasia.

Sun F, Wang G, Pradhan A, Xu K, Gomez-Arroyo J, Zhang Y, Kalin GT, Deng Z, Vagnozzi RJ, He H, Dunn AW, Wang Y, York AJ, Hegde RS, Woods JC, Kalin TV, Molkentin JD, Kalinichenko VV
Circulation 2021 Aug 17;144(7):539-555. Epub 2021 Jun 11 doi: 10.1161/CIRCULATIONAHA.121.053980. PMID: 34111939 Free PMC Article

Proteomics in idiopathic pulmonary fibrosis: the quest for biomarkers.

Khan T, Dasgupta S, Ghosh N, Chaudhury K
Mol Omics 2021 Feb 22;17(1):43-58. doi: 10.1039/d0mo00108b. PMID: 33073811

Leptospirosis in humans.

Haake DA, Levett PN
Curr Top Microbiol Immunol 2015;387:65-97. doi: 10.1007/978-3-662-45059-8_5. PMID: 25388133 Free PMC Article

Acute respiratory distress syndrome.

Monahan LJ
Curr Probl Pediatr Adolesc Health Care 2013 Nov-Dec;43(10):278-84. doi: 10.1016/j.cppeds.2013.10.004. PMID: 24295609

See all (33)

Therapy

Nicotine replacement therapy and e-cigarettes in pregnancy and infant respiratory outcomes.

Bednarczuk N, Williams EE, Dassios T, Greenough A
Early Hum Dev 2022 Jan;164:105509. Epub 2021 Nov 20 doi: 10.1016/j.earlhumdev.2021.105509. PMID: 34823165

Chronic E-Cigarette Exposure Alters Human Alveolar Macrophage Morphology and Gene Expression.

Davis ES, Ghosh A, Coakley RD, Wrennall JA, Lubamba BA, Rowell TR, Dang H, Pawlak EA, Li Q, Alexis NE, Ribeiro CMP, Tarran R
Nicotine Tob Res 2022 Feb 14;24(3):395-399. doi: 10.1093/ntr/ntab186. PMID: 34519792 Free PMC Article

Nanoparticle Delivery of STAT3 Alleviates Pulmonary Hypertension in a Mouse Model of Alveolar Capillary Dysplasia.

Aerosolized Medications for Gene and Peptide Therapy.

Laube BL
Respir Care 2015 Jun;60(6):806-21; discussion 821-4. doi: 10.4187/respcare.03554. PMID: 26070576

Pulmonary complications of smoked substance abuse.

Tashkin DP
West J Med 1990 May;152(5):525-30. PMID: 2190420 Free PMC Article

See all (28)

Prognosis

Proteomics in idiopathic pulmonary fibrosis: the quest for biomarkers.

Khan T, Dasgupta S, Ghosh N, Chaudhury K
Mol Omics 2021 Feb 22;17(1):43-58. doi: 10.1039/d0mo00108b. PMID: 33073811

Acute respiratory distress syndrome.

Monahan LJ
Curr Probl Pediatr Adolesc Health Care 2013 Nov-Dec;43(10):278-84. doi: 10.1016/j.cppeds.2013.10.004. PMID: 24295609

Idiopathic pulmonary fibrosis-an epidemiological and pathological review.

Borchers AT, Chang C, Keen CL, Gershwin ME
Clin Rev Allergy Immunol 2011 Apr;40(2):117-34. doi: 10.1007/s12016-010-8211-5. PMID: 20838937

Surfactant and the adult respiratory distress syndrome.

Lewis JF, Jobe AH
Am Rev Respir Dis 1993 Jan;147(1):218-33. doi: 10.1164/ajrccm/147.1.218. PMID: 8420422

Fetal lung development in the diabetic pregnancy.

Bourbon JR, Farrell PM
Pediatr Res 1985 Mar;19(3):253-67. doi: 10.1203/00006450-198503000-00001. PMID: 3885150

See all (22)

Clinical prediction guides

Conditional knockout of ITGB4 in bronchial epithelial cells directs bronchopulmonary dysplasia.

Quantification of pulmonary functional MRI: state-of-the-art and emerging image processing methods and measurements.

Sharma M, Wyszkiewicz PV, Desaigoudar V, Guo F, Capaldi DP, Parraga G
Phys Med Biol 2022 Nov 7;67(22) doi: 10.1088/1361-6560/ac9510. PMID: 36162409

Nicotine replacement therapy and e-cigarettes in pregnancy and infant respiratory outcomes.

Bednarczuk N, Williams EE, Dassios T, Greenough A
Early Hum Dev 2022 Jan;164:105509. Epub 2021 Nov 20 doi: 10.1016/j.earlhumdev.2021.105509. PMID: 34823165

Lung disease manifestations in Down syndrome.

Danopoulos S, Deutsch GH, Dumortier C, Mariani TJ, Al Alam D
Am J Physiol Lung Cell Mol Physiol 2021 Nov 1;321(5):L892-L899. Epub 2021 Sep 1 doi: 10.1152/ajplung.00434.2020. PMID: 34469245 Free PMC Article

Acute respiratory distress syndrome.

Monahan LJ
Curr Probl Pediatr Adolesc Health Care 2013 Nov-Dec;43(10):278-84. doi: 10.1016/j.cppeds.2013.10.004. PMID: 24295609

See all (25)

Recent systematic reviews

p38 MAPK signaling in chronic obstructive pulmonary disease pathogenesis and inhibitor therapeutics.

Ahmadi A, Ahrari S, Salimian J, Salehi Z, Karimi M, Emamvirdizadeh A, Jamalkandi SA, Ghanei M
Cell Commun Signal 2023 Nov 2;21(1):314. doi: 10.1186/s12964-023-01337-4. PMID: 37919729 Free PMC Article

Targeting the NO-cGMP-PDE5 pathway in COVID-19 infection. The DEDALO project.

Isidori AM, Giannetta E, Pofi R, Venneri MA, Gianfrilli D, Campolo F, Mastroianni CM, Lenzi A, d'Ettorre G
Andrology 2021 Jan;9(1):33-38. Epub 2020 Jul 3 doi: 10.1111/andr.12837. PMID: 32526061 Free PMC Article

See all (2)

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Abnormal pulmonary alveolar system development

Term Hierarchy

Professional guidelines

PubMed

Recent clinical studies

Etiology

Diagnosis

Therapy

Prognosis

Clinical prediction guides

Recent systematic reviews

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Clinical resources

Practice guidelines

Consumer resources

Reviews

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