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Elevated forced expiratory volume in one second

MedGen UID:
1788455
•Concept ID:
C5539533
•
Finding
Synonym: Elevated FEV1
 
HPO: HP:0033350

Definition

An increase in the amount of air a person can forcefully expel in one second, compared to some standard or previous measure of same subject. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVElevated forced expiratory volume in one second

Professional guidelines

PubMed

The pharmacological management of asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS).
Albertson TE, Chenoweth JA, Pearson SJ, Murin S
Expert Opin Pharmacother 2020 Feb;21(2):213-231. doi: 10.1080/14656566.2019.1701656. PMID: 31955671
Overcoming gaps in the management of chronic obstructive pulmonary disease in older patients: new insights.
Gelberg J, McIvor RA
Drugs Aging 2010 May;27(5):367-75. doi: 10.2165/11535220-000000000-00000. PMID: 20450235
Benefit-risk assessment of antileukotrienes in the management of asthma.
García-Marcos L, Schuster A, Pérez-Yarza EG
Drug Saf 2003;26(7):483-518. doi: 10.2165/00002018-200326070-00004. PMID: 12735786

Recent clinical studies

Etiology

Common physiologic and proteomic biomarkers in pulmonary and coronary artery disease.
Casselbrant A, Fedorowski A, Frantz S, Engström G, Wollmer P, Hamrefors V
PLoS One 2022;17(3):e0264376. Epub 2022 Mar 9 doi: 10.1371/journal.pone.0264376. PMID: 35263363Free PMC Article
Regulation of lung epithelial cell senescence in smoking-induced COPD/emphysema by microR-125a-5p via Sp1 mediation of SIRT1/HIF-1a.
Wu H, Ma H, Wang L, Zhang H, Lu L, Xiao T, Cheng C, Wang P, Yang Y, Wu M, Wang S, Zhang J, Liu Q
Int J Biol Sci 2022;18(2):661-674. Epub 2022 Jan 1 doi: 10.7150/ijbs.65861. PMID: 35002516Free PMC Article
Triple Therapy for Cystic Fibrosis Phe508del-Gating and -Residual Function Genotypes.
Barry PJ, Mall MA, Álvarez A, Colombo C, de Winter-de Groot KM, Fajac I, McBennett KA, McKone EF, Ramsey BW, Sutharsan S, Taylor-Cousar JL, Tullis E, Ahluwalia N, Jun LS, Moskowitz SM, Prieto-Centurion V, Tian S, Waltz D, Xuan F, Zhang Y, Rowe SM, Polineni D; VX18-445-104 Study Group
N Engl J Med 2021 Aug 26;385(9):815-825. doi: 10.1056/NEJMoa2100665. PMID: 34437784Free PMC Article
Association between elevated serum triglycerides and asthma in patients with obesity: An explorative study.
van Zelst CM, de Boer GM, Türk Y, van Huisstede A, In't Veen JCCM, Birnie E, Boxma-de Klerk BM, Tramper-Stranders GA, Braunstahl GJ
Allergy Asthma Proc 2021 May 1;42(3):e71-e76. doi: 10.2500/aap.2021.42.210020. PMID: 33980342
The pharmacological management of asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS).
Albertson TE, Chenoweth JA, Pearson SJ, Murin S
Expert Opin Pharmacother 2020 Feb;21(2):213-231. doi: 10.1080/14656566.2019.1701656. PMID: 31955671

Diagnosis

A2M Serves as Promising Biomarker for Chronic Obstructive Pulmonary Disease.
Xiao X, Cai W, Ding Z, Shi Y, Fan L, Zhang Q
Int J Chron Obstruct Pulmon Dis 2023;18:683-692. Epub 2023 Apr 24 doi: 10.2147/COPD.S407491. PMID: 37123074Free PMC Article
Common physiologic and proteomic biomarkers in pulmonary and coronary artery disease.
Casselbrant A, Fedorowski A, Frantz S, Engström G, Wollmer P, Hamrefors V
PLoS One 2022;17(3):e0264376. Epub 2022 Mar 9 doi: 10.1371/journal.pone.0264376. PMID: 35263363Free PMC Article
Prevalence and clinical implications of bronchiectasis in patients with overlapping asthma and chronic rhinosinusitis: a single-center prospective study.
Sheng H, Yao X, Wang X, Wang Y, Liu X, Zhang L
BMC Pulm Med 2021 Jul 5;21(1):211. doi: 10.1186/s12890-021-01575-7. PMID: 34225679Free PMC Article
Association between elevated serum triglycerides and asthma in patients with obesity: An explorative study.
van Zelst CM, de Boer GM, Türk Y, van Huisstede A, In't Veen JCCM, Birnie E, Boxma-de Klerk BM, Tramper-Stranders GA, Braunstahl GJ
Allergy Asthma Proc 2021 May 1;42(3):e71-e76. doi: 10.2500/aap.2021.42.210020. PMID: 33980342
Noninvasive ventilation acutely improves endothelial function in exacerbated COPD patients.
Heubel AD, Kabbach EZ, Schafauser NS, Phillips SA, Pires Di Lorenzo VA, Borghi Silva A, Mendes RG
Respir Med 2021 May;181:106389. Epub 2021 Apr 2 doi: 10.1016/j.rmed.2021.106389. PMID: 33831730

Therapy

Regulation of lung epithelial cell senescence in smoking-induced COPD/emphysema by microR-125a-5p via Sp1 mediation of SIRT1/HIF-1a.
Wu H, Ma H, Wang L, Zhang H, Lu L, Xiao T, Cheng C, Wang P, Yang Y, Wu M, Wang S, Zhang J, Liu Q
Int J Biol Sci 2022;18(2):661-674. Epub 2022 Jan 1 doi: 10.7150/ijbs.65861. PMID: 35002516Free PMC Article
Triple Therapy for Cystic Fibrosis Phe508del-Gating and -Residual Function Genotypes.
Barry PJ, Mall MA, Álvarez A, Colombo C, de Winter-de Groot KM, Fajac I, McBennett KA, McKone EF, Ramsey BW, Sutharsan S, Taylor-Cousar JL, Tullis E, Ahluwalia N, Jun LS, Moskowitz SM, Prieto-Centurion V, Tian S, Waltz D, Xuan F, Zhang Y, Rowe SM, Polineni D; VX18-445-104 Study Group
N Engl J Med 2021 Aug 26;385(9):815-825. doi: 10.1056/NEJMoa2100665. PMID: 34437784Free PMC Article
Association between elevated serum triglycerides and asthma in patients with obesity: An explorative study.
van Zelst CM, de Boer GM, Türk Y, van Huisstede A, In't Veen JCCM, Birnie E, Boxma-de Klerk BM, Tramper-Stranders GA, Braunstahl GJ
Allergy Asthma Proc 2021 May 1;42(3):e71-e76. doi: 10.2500/aap.2021.42.210020. PMID: 33980342
The pharmacological management of asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS).
Albertson TE, Chenoweth JA, Pearson SJ, Murin S
Expert Opin Pharmacother 2020 Feb;21(2):213-231. doi: 10.1080/14656566.2019.1701656. PMID: 31955671
Annexin A1 is elevated in patients with COPD and affects lung fibroblast function.
Lai T, Li Y, Mai Z, Wen X, Lv Y, Xie Z, Lv Q, Chen M, Wu D, Wu B
Int J Chron Obstruct Pulmon Dis 2018;13:473-486. Epub 2018 Feb 5 doi: 10.2147/COPD.S149766. PMID: 29440885Free PMC Article

Prognosis

A2M Serves as Promising Biomarker for Chronic Obstructive Pulmonary Disease.
Xiao X, Cai W, Ding Z, Shi Y, Fan L, Zhang Q
Int J Chron Obstruct Pulmon Dis 2023;18:683-692. Epub 2023 Apr 24 doi: 10.2147/COPD.S407491. PMID: 37123074Free PMC Article
Prevalence and associations among metabolically unhealthy obesity, asthma exacerbations, and emergency department use.
Greiner B, Hartwell M
Ann Allergy Asthma Immunol 2022 Nov;129(5):580-584.e2. Epub 2022 Jul 14 doi: 10.1016/j.anai.2022.07.005. PMID: 35843518
Triple Therapy for Cystic Fibrosis Phe508del-Gating and -Residual Function Genotypes.
Barry PJ, Mall MA, Álvarez A, Colombo C, de Winter-de Groot KM, Fajac I, McBennett KA, McKone EF, Ramsey BW, Sutharsan S, Taylor-Cousar JL, Tullis E, Ahluwalia N, Jun LS, Moskowitz SM, Prieto-Centurion V, Tian S, Waltz D, Xuan F, Zhang Y, Rowe SM, Polineni D; VX18-445-104 Study Group
N Engl J Med 2021 Aug 26;385(9):815-825. doi: 10.1056/NEJMoa2100665. PMID: 34437784Free PMC Article
Noninvasive ventilation acutely improves endothelial function in exacerbated COPD patients.
Heubel AD, Kabbach EZ, Schafauser NS, Phillips SA, Pires Di Lorenzo VA, Borghi Silva A, Mendes RG
Respir Med 2021 May;181:106389. Epub 2021 Apr 2 doi: 10.1016/j.rmed.2021.106389. PMID: 33831730
Annexin A1 is elevated in patients with COPD and affects lung fibroblast function.
Lai T, Li Y, Mai Z, Wen X, Lv Y, Xie Z, Lv Q, Chen M, Wu D, Wu B
Int J Chron Obstruct Pulmon Dis 2018;13:473-486. Epub 2018 Feb 5 doi: 10.2147/COPD.S149766. PMID: 29440885Free PMC Article

Clinical prediction guides

A2M Serves as Promising Biomarker for Chronic Obstructive Pulmonary Disease.
Xiao X, Cai W, Ding Z, Shi Y, Fan L, Zhang Q
Int J Chron Obstruct Pulmon Dis 2023;18:683-692. Epub 2023 Apr 24 doi: 10.2147/COPD.S407491. PMID: 37123074Free PMC Article
Triple Therapy for Cystic Fibrosis Phe508del-Gating and -Residual Function Genotypes.
Barry PJ, Mall MA, Álvarez A, Colombo C, de Winter-de Groot KM, Fajac I, McBennett KA, McKone EF, Ramsey BW, Sutharsan S, Taylor-Cousar JL, Tullis E, Ahluwalia N, Jun LS, Moskowitz SM, Prieto-Centurion V, Tian S, Waltz D, Xuan F, Zhang Y, Rowe SM, Polineni D; VX18-445-104 Study Group
N Engl J Med 2021 Aug 26;385(9):815-825. doi: 10.1056/NEJMoa2100665. PMID: 34437784Free PMC Article
Prevalence and clinical implications of bronchiectasis in patients with overlapping asthma and chronic rhinosinusitis: a single-center prospective study.
Sheng H, Yao X, Wang X, Wang Y, Liu X, Zhang L
BMC Pulm Med 2021 Jul 5;21(1):211. doi: 10.1186/s12890-021-01575-7. PMID: 34225679Free PMC Article
Noninvasive ventilation acutely improves endothelial function in exacerbated COPD patients.
Heubel AD, Kabbach EZ, Schafauser NS, Phillips SA, Pires Di Lorenzo VA, Borghi Silva A, Mendes RG
Respir Med 2021 May;181:106389. Epub 2021 Apr 2 doi: 10.1016/j.rmed.2021.106389. PMID: 33831730
Annexin A1 is elevated in patients with COPD and affects lung fibroblast function.
Lai T, Li Y, Mai Z, Wen X, Lv Y, Xie Z, Lv Q, Chen M, Wu D, Wu B
Int J Chron Obstruct Pulmon Dis 2018;13:473-486. Epub 2018 Feb 5 doi: 10.2147/COPD.S149766. PMID: 29440885Free PMC Article

Recent systematic reviews

High-flow nasal cannula therapy versus conventional oxygen therapy for adult patients after cardiac surgery: A systemic review and meta-analysis.
Liu C, Lin Q, Li D
Heart Lung 2024 Jun-Aug;66:47-55. Epub 2024 Apr 6 doi: 10.1016/j.hrtlng.2024.03.008. PMID: 38582067
Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease.
Pollok J, van Agteren JE, Carson-Chahhoud KV
Cochrane Database Syst Rev 2018 Dec 19;12(12):CD012346. doi: 10.1002/14651858.CD012346.pub2. PMID: 30566235Free PMC Article
Amino terminal pro brain natriuretic peptide predicts all-cause mortality in patients with chronic obstructive pulmonary disease: Systematic review and meta-analysis.
Pavasini R, Tavazzi G, Biscaglia S, Guerra F, Pecoraro A, Zaraket F, Gallo F, Spitaleri G, Contoli M, Ferrari R, Campo G
Chron Respir Dis 2017 May;14(2):117-126. Epub 2016 Dec 15 doi: 10.1177/1479972316674393. PMID: 27956645Free PMC Article

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