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Lower extremity akinesia

MedGen UID:
1788495
•Concept ID:
C5539572
•
Finding
HPO: HP:0033411

Definition

Inability to initiate changes in activity or movement and to perform ordinary volitional movements rapidly and easily in the lower extremities. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLower extremity akinesia

Recent clinical studies

Etiology

Transmission of group II heteronymous pathways is enhanced in rigid lower limb of de novo patients with Parkinson's disease.
Simonetta Moreau M, Meunier S, Vidailhet M, Pol S, Galitzky M, Rascol O
Brain 2002 Sep;125(Pt 9):2125-33. doi: 10.1093/brain/awf201. PMID: 12183357

Diagnosis

Giant right coronary artery aneurysm mimicking a right intra-ventricular mass: a case report.
Teng P, Ni C, Sun Q, Ni Y
J Cardiothorac Surg 2020 Jan 13;15(1):17. doi: 10.1186/s13019-020-1054-0. PMID: 31931838Free PMC Article
Amantadine-induced livedo reticularis: a report of two cases.
Hayes BB, Cook-Norris RH, Miller JL, Rodriguez A, Zic JA
J Drugs Dermatol 2006 Mar;5(3):288-9. PMID: 16573266
Progressive neurodegenerative disease in presumed spinal cord injury: case report of a patient with prion disease.
Grant D, Loomis S
J Spinal Cord Med 2003 Fall;26(3):259-61. doi: 10.1080/10790268.2003.11753694. PMID: 14997969
Leg manifestation in alien hand syndrome.
Chan JL, Chen RS, Ng KK
J Formos Med Assoc 1996 Apr;95(4):342-6. PMID: 8935307

Therapy

Effects of Repetitive Transcranial Magnetic Stimulation on Motor Symptoms in Parkinson's Disease: A Meta-Analysis.
Li R, He Y, Qin W, Zhang Z, Su J, Guan Q, Chen Y, Jin L
Neurorehabil Neural Repair 2022 Jul;36(7):395-404. Epub 2022 May 26 doi: 10.1177/15459683221095034. PMID: 35616427
Gait bradykinesia: difficulty in switching posture/gait measured by the anatomical y-axis vector of the sole in Parkinson's disease.
Warabi T, Furuyama H, Kato M
Exp Brain Res 2020 Jan;238(1):139-151. Epub 2019 Dec 10 doi: 10.1007/s00221-019-05704-x. PMID: 31822932
Amantadine-induced livedo reticularis: a report of two cases.
Hayes BB, Cook-Norris RH, Miller JL, Rodriguez A, Zic JA
J Drugs Dermatol 2006 Mar;5(3):288-9. PMID: 16573266
Characterization of freezing of gait subtypes and the response of each to levodopa in Parkinson's disease.
Schaafsma JD, Balash Y, Gurevich T, Bartels AL, Hausdorff JM, Giladi N
Eur J Neurol 2003 Jul;10(4):391-8. doi: 10.1046/j.1468-1331.2003.00611.x. PMID: 12823491
Do parkinsonian symptoms and levodopa-induced dyskinesias start in the foot?
Vidailhet M, Bonnet AM, Marconi R, Gouider-Khouja N, Agid Y
Neurology 1994 Sep;44(9):1613-6. doi: 10.1212/wnl.44.9.1613. PMID: 7936284

Prognosis

Transmission of group II heteronymous pathways is enhanced in rigid lower limb of de novo patients with Parkinson's disease.
Simonetta Moreau M, Meunier S, Vidailhet M, Pol S, Galitzky M, Rascol O
Brain 2002 Sep;125(Pt 9):2125-33. doi: 10.1093/brain/awf201. PMID: 12183357

Clinical prediction guides

Characterization of freezing of gait subtypes and the response of each to levodopa in Parkinson's disease.
Schaafsma JD, Balash Y, Gurevich T, Bartels AL, Hausdorff JM, Giladi N
Eur J Neurol 2003 Jul;10(4):391-8. doi: 10.1046/j.1468-1331.2003.00611.x. PMID: 12823491
Transmission of group II heteronymous pathways is enhanced in rigid lower limb of de novo patients with Parkinson's disease.
Simonetta Moreau M, Meunier S, Vidailhet M, Pol S, Galitzky M, Rascol O
Brain 2002 Sep;125(Pt 9):2125-33. doi: 10.1093/brain/awf201. PMID: 12183357

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