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Superior mediastinal mass

MedGen UID:
1788967
•Concept ID:
C2062854
•
Finding
HPO: HP:0033825

Definition

A type of mediastinal mass that is located above the thoracic plane (a horizontal line that runs from the manubriosternal joint (sternal angle or angle of Louis) to the inferior endplate of T4). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSuperior mediastinal mass

Professional guidelines

PubMed

Study of superior vena cava syndrome--aetiopathology, diagnosis and management.
Tayade BO, Salvi SS, Agarwal IR
J Assoc Physicians India 1994 Aug;42(8):609-11. PMID: 7868553
Pseudocoarctation of the aorta. An important consideration in the differential diagnosis of superior mediastinal mass.
Cheng TO
Am J Med 1970 Oct;49(4):551-5. doi: 10.1016/s0002-9343(70)80050-x. PMID: 5477640

Recent clinical studies

Etiology

Fibrovascular polyps of the esophagus: clinical, radiographic, and pathologic findings in 16 patients.
Levine MS, Buck JL, Pantongrag-Brown L, Buetow PC, Hallman JR, Sobin LH
AJR Am J Roentgenol 1996 Apr;166(4):781-7. doi: 10.2214/ajr.166.4.8610549. PMID: 8610549
Aneurysm of aberrant subclavian artery with a review of the literature.
Austin EH, Wolfe WG
J Vasc Surg 1985 Jul;2(4):571-7. doi: 10.1067/mva.1985.avs0020571. PMID: 3892054
Invasive thymoma: unique presentation as an anterior chest wall mass.
Oldroyd KG, Spiers AS, Hussain M
Clin Oncol 1983 Jun;9(2):169-76. PMID: 6883842

Diagnosis

Diagnostic Challenge and Management of Thymic Cavernous Hemangioma: A Case Report and Review of the Literature.
Liu L, Zhang F, Wu Z, Tu S, Li Y
Curr Med Imaging 2023;19(12):1463-1467. doi: 10.2174/1573405619666230109121128. PMID: 36624647
Primary epithelioid angiosarcoma of the mediastinum, cytomorphologic features of a rare entity-A case report and literature review.
Vats K, Al-Nourhji O, Wang H, Wang C
Diagn Cytopathol 2022 Jul;50(7):E181-E187. Epub 2022 Feb 9 doi: 10.1002/dc.24946. PMID: 35142097
An Unusual Schwannoma.
Waghmare SK, Desai U, Karkhanis VS, Amonkar G, Joshi JM
J Assoc Physicians India 2017 Jun;65(6):92-94. PMID: 28782320
Study of superior vena cava syndrome--aetiopathology, diagnosis and management.
Tayade BO, Salvi SS, Agarwal IR
J Assoc Physicians India 1994 Aug;42(8):609-11. PMID: 7868553
Aneurysm of aberrant subclavian artery with a review of the literature.
Austin EH, Wolfe WG
J Vasc Surg 1985 Jul;2(4):571-7. doi: 10.1067/mva.1985.avs0020571. PMID: 3892054

Therapy

Myasthenia Gravis with Toxic Goiter: Challenges with Management in a Low-Resource Setting in Africa; Review of Literature and Case Report.
Akerele JM, Erameh C, Okomayin AA, Dongo A, Omosofe F, Ikponmonsa G, Osemobor KO, Akerele NN, Ngwu S
Niger J Clin Pract 2024 Jan 1;27(1):148-152. Epub 2024 Feb 5 doi: 10.4103/njcp.njcp_206_23. PMID: 38317049
Incidental radiologic finding of an anterior superior mediastinal mass masquerading as metastatic thyroid cancer in patients with treated thyroid cancer.
McCullen MK, Miller JL
Endocr Pract 2011 Jan-Feb;17(1):65-9. doi: 10.4158/EP10111.OR. PMID: 20713344
Superior mediastinal mass in a 14-year-old male child.
Gaur SN, Ray DP, Dusaj IS
Indian J Chest Dis Allied Sci 1996 Jul-Sep;38(3):191-5. PMID: 8987293
Invasive thymoma: unique presentation as an anterior chest wall mass.
Oldroyd KG, Spiers AS, Hussain M
Clin Oncol 1983 Jun;9(2):169-76. PMID: 6883842
Aneurysm of the subclavian artery: a complication of retrograde brachial artery catheterization.
Chiavacci WE, Bucciarelli RL, Victorica BE
Cathet Cardiovasc Diagn 1976;2(1):93-6. doi: 10.1002/ccd.1810020112. PMID: 1260856

Prognosis

Branchial cysts: an unusual cause of a mediastinal mass: a case report.
Kotecha V, Muturi A, Ruturi J
J Med Case Rep 2015 Sep 29;9:208. doi: 10.1186/s13256-015-0680-y. PMID: 26416666Free PMC Article
Benign mediastinal lymphadenopathy presenting as cor triatriatum.
Noel CV, Pollard J, Permut L, Ferguson M, Hattendorf B
Congenit Heart Dis 2013 May-Jun;8(3):E70-2. Epub 2012 Feb 7 doi: 10.1111/j.1747-0803.2011.00627.x. PMID: 22309222
Incidental radiologic finding of an anterior superior mediastinal mass masquerading as metastatic thyroid cancer in patients with treated thyroid cancer.
McCullen MK, Miller JL
Endocr Pract 2011 Jan-Feb;17(1):65-9. doi: 10.4158/EP10111.OR. PMID: 20713344
Superior vena cava obstruction: dangers of a missed diagnosis.
Holme H, Nanduri V
J Paediatr Child Health 2011 Mar;47(3):150-1. doi: 10.1111/j.1440-1754.2010.01741.x. PMID: 20500430
Aneurysm of aberrant subclavian artery with a review of the literature.
Austin EH, Wolfe WG
J Vasc Surg 1985 Jul;2(4):571-7. doi: 10.1067/mva.1985.avs0020571. PMID: 3892054

Clinical prediction guides

Benign mediastinal lymphadenopathy presenting as cor triatriatum.
Noel CV, Pollard J, Permut L, Ferguson M, Hattendorf B
Congenit Heart Dis 2013 May-Jun;8(3):E70-2. Epub 2012 Feb 7 doi: 10.1111/j.1747-0803.2011.00627.x. PMID: 22309222
Primary leiomyosarcoma of the anterior mediastinum encasing the aortic arch, left common carotid and left subclavian arteries.
Iwata T, Miura T, Inoue K, Hanada S, Inoue H, Miyamoto Y
Ann Thorac Cardiovasc Surg 2012;18(2):140-3. Epub 2011 Oct 28 doi: 10.5761/atcs.cr.11.01710. PMID: 22033241
Lambert-Eaton myasthenic syndrome and follicular thymic hyperplasia in systemic lupus erythematosus.
Pasqualoni E, Aubart F, Brihaye B, Sacré K, Maisonobe T, Laissy JP, Lidove O, Papo T
Lupus 2011 Jun;20(7):745-8. Epub 2011 Mar 22 doi: 10.1177/0961203310393769. PMID: 21427136
Fine-needle aspiration cytology of primary large-cell lymphoma of the mediastinum: cytomorphologic findings with potential pitfalls in diagnosis.
Silverman JF, Raab SS, Park HK
Diagn Cytopathol 1993;9(2):209-14; discussion 214-5. doi: 10.1002/dc.2840090221. PMID: 8513716

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