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Ovarian Mixed Cell Adenocarcinoma

MedGen UID:
1792063
Concept ID:
C5555622
Neoplastic Process
Synonym: Ovarian Mixed Carcinoma

Definition

An adenocarcinoma that arises from the ovary and is characterized by the presence of two or more adenocarcinoma components, most often endometrioid and clear cell. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVOvarian Mixed Cell Adenocarcinoma

Professional guidelines

PubMed

Wang X, Wang S, Yao S, Shi W, Ma K
J Ovarian Res 2022 Sep 16;15(1):104. doi: 10.1186/s13048-022-01037-6. PMID: 36114551Free PMC Article
Friedlander ML, Russell K, Millis S, Gatalica Z, Bender R, Voss A
Int J Gynecol Cancer 2016 May;26(4):648-54. doi: 10.1097/IGC.0000000000000677. PMID: 26937756Free PMC Article
Garrett LA, Growdon WB, Goodman A, Boruta DM, Schorge JO, del Carmen MG
J Reprod Med 2013 Nov-Dec;58(11-12):469-76. PMID: 24568040

Recent clinical studies

Etiology

Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
J Gynecol Oncol 2023 Sep;34(5):e85. Epub 2023 Aug 8 doi: 10.3802/jgo.2023.34.e85. PMID: 37593813Free PMC Article
Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
Int J Gynaecol Obstet 2023 Aug;162(2):383-394. Epub 2023 Jun 20 doi: 10.1002/ijgo.14923. PMID: 37337978
Zhou L, Yao L, Dai L, Zhu H, Ye X, Wang S, Cheng H, Ma R, Liu H, Cui H, Chang X
J Ovarian Res 2021 May 4;14(1):63. doi: 10.1186/s13048-021-00804-1. PMID: 33941230Free PMC Article
Devouassoux-Shisheboran M, Genestie C
Chin J Cancer 2015 Jan;34(1):50-5. doi: 10.5732/cjc.014.10273. PMID: 25556618Free PMC Article
Kaku T, Ogawa S, Kawano Y, Ohishi Y, Kobayashi H, Hirakawa T, Nakano H
Med Electron Microsc 2003 Mar;36(1):9-17. doi: 10.1007/s007950300002. PMID: 12658347

Diagnosis

Wang X, Wang S, Yao S, Shi W, Ma K
J Ovarian Res 2022 Sep 16;15(1):104. doi: 10.1186/s13048-022-01037-6. PMID: 36114551Free PMC Article
Zhou L, Yao L, Dai L, Zhu H, Ye X, Wang S, Cheng H, Ma R, Liu H, Cui H, Chang X
J Ovarian Res 2021 May 4;14(1):63. doi: 10.1186/s13048-021-00804-1. PMID: 33941230Free PMC Article
Matias-Guiu X, Stewart CJR
Pathology 2018 Feb;50(2):190-204. Epub 2017 Dec 11 doi: 10.1016/j.pathol.2017.10.006. PMID: 29241974
Helder-Woolderink JM, Blok EA, Vasen HF, Hollema H, Mourits MJ, De Bock GH
Eur J Cancer 2016 Mar;55:65-73. Epub 2016 Jan 13 doi: 10.1016/j.ejca.2015.12.005. PMID: 26773421
Bartosch C, Manuel Lopes J, Oliva E
Adv Anat Pathol 2011 Nov;18(6):415-37. doi: 10.1097/PAP.0b013e318234ab18. PMID: 21993268

Therapy

Wang X, Wang S, Yao S, Shi W, Ma K
J Ovarian Res 2022 Sep 16;15(1):104. doi: 10.1186/s13048-022-01037-6. PMID: 36114551Free PMC Article
Tsuruga T, Hirata T, Akiyama I, Matsumoto Y, Oda K, Fujii T, Osuga Y
J Obstet Gynaecol Res 2019 Aug;45(8):1613-1618. Epub 2019 Jun 10 doi: 10.1111/jog.14014. PMID: 31183953
Takenaka M, Köbel M, Garsed DW, Fereday S, Pandey A, Etemadmoghadam D, Hendley J, Kawabata A, Noguchi D, Yanaihara N, Takahashi H, Kiyokawa T, Ikegami M, Takano H, Isonishi S, Ochiai K, Traficante N, Gadipally S, Semple T, Vassiliadis D, Amarasinghe K, Li J, Mir Arnau G, Okamoto A, Friedlander M, Bowtell DDL; Australian Ovarian Cancer Study Group
Clin Cancer Res 2019 Jul 1;25(13):3962-3973. Epub 2019 Apr 9 doi: 10.1158/1078-0432.CCR-18-3691. PMID: 30967419
Karami S, Daughtery SE, Schwartz K, Davis FG, Ruterbusch JJ, Wacholder S, Graubard BI, Berndt SI, Hofmann JN, Purdue MP, Moore LE, Colt JS
Int J Cancer 2016 Aug 1;139(3):584-92. Epub 2016 Apr 9 doi: 10.1002/ijc.30108. PMID: 27009534Free PMC Article
Kucukgoz Gulec U, Paydas S, Guzel AB, Vardar MA, Khatib G, Gumurdulu D
Arch Gynecol Obstet 2015 Oct;292(4):923-9. Epub 2015 Apr 9 doi: 10.1007/s00404-015-3699-9. PMID: 25855053

Prognosis

Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
J Gynecol Oncol 2023 Sep;34(5):e85. Epub 2023 Aug 8 doi: 10.3802/jgo.2023.34.e85. PMID: 37593813Free PMC Article
Berek JS, Matias-Guiu X, Creutzberg C, Fotopoulou C, Gaffney D, Kehoe S, Lindemann K, Mutch D, Concin N; Endometrial Cancer Staging Subcommittee, FIGO Women's Cancer Committee
Int J Gynaecol Obstet 2023 Aug;162(2):383-394. Epub 2023 Jun 20 doi: 10.1002/ijgo.14923. PMID: 37337978
Wang X, Wang S, Yao S, Shi W, Ma K
J Ovarian Res 2022 Sep 16;15(1):104. doi: 10.1186/s13048-022-01037-6. PMID: 36114551Free PMC Article
Liu X, Zhang X, Pang Y, Ma Y, Zhang X, Liu P
Arch Gynecol Obstet 2020 Apr;301(4):901-912. Epub 2020 Mar 17 doi: 10.1007/s00404-020-05502-9. PMID: 32185550
Matias-Guiu X, Stewart CJR
Pathology 2018 Feb;50(2):190-204. Epub 2017 Dec 11 doi: 10.1016/j.pathol.2017.10.006. PMID: 29241974

Clinical prediction guides

Mirkovic J, Olkhov-Mitsel E, Amemiya Y, Al-Hussaini M, Nofech-Mozes S, Djordjevic B, Kupets R, Seth A, McCluggage WG
Histopathology 2023 Jun;82(7):978-990. Epub 2023 Mar 31 doi: 10.1111/his.14892. PMID: 36860193
Wu H, Jiang S, Zhong P, Li W, Zhang S
J Ovarian Res 2021 Oct 21;14(1):137. doi: 10.1186/s13048-021-00896-9. PMID: 34674727Free PMC Article
Sensu S, Keser SH, Gurbuz Y, Barisik NO, Gul AE
Arch Iran Med 2021 Apr 1;24(4):301-305. doi: 10.34172/aim.2021.42. PMID: 34196190
Matias-Guiu X, Stewart CJR
Pathology 2018 Feb;50(2):190-204. Epub 2017 Dec 11 doi: 10.1016/j.pathol.2017.10.006. PMID: 29241974
Helder-Woolderink JM, Blok EA, Vasen HF, Hollema H, Mourits MJ, De Bock GH
Eur J Cancer 2016 Mar;55:65-73. Epub 2016 Jan 13 doi: 10.1016/j.ejca.2015.12.005. PMID: 26773421

Recent systematic reviews

Wang X, Wang S, Yao S, Shi W, Ma K
J Ovarian Res 2022 Sep 16;15(1):104. doi: 10.1186/s13048-022-01037-6. PMID: 36114551Free PMC Article
Helder-Woolderink JM, Blok EA, Vasen HF, Hollema H, Mourits MJ, De Bock GH
Eur J Cancer 2016 Mar;55:65-73. Epub 2016 Jan 13 doi: 10.1016/j.ejca.2015.12.005. PMID: 26773421

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