U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Recurrent Malignant Scrotal Neoplasm

MedGen UID:
1792151
•Concept ID:
C5555710
•
Neoplastic Process

Definition

The reemergence of a malignant scrotal neoplasm after a period of remission. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVRecurrent Malignant Scrotal Neoplasm

Professional guidelines

PubMed

Interventional Radiology: Indications and Best Practices.
Arnold MJ, Keung JJ, McCarragher B
Am Fam Physician 2019 May 1;99(9):547-556. PMID: 31038901
Testicular Cancer: Diagnosis and Treatment.
Baird DC, Meyers GJ, Hu JS
Am Fam Physician 2018 Feb 15;97(4):261-268. PMID: 29671528
Diagnosis and management of spermatic cord tumors.
Moschini M, Mattei A
Curr Opin Urol 2017 Jan;27(1):76-79. doi: 10.1097/MOU.0000000000000318. PMID: 27262142

Recent clinical studies

Etiology

Interventional Radiology: Indications and Best Practices.
Arnold MJ, Keung JJ, McCarragher B
Am Fam Physician 2019 May 1;99(9):547-556. PMID: 31038901
Testicular Cancer: Diagnosis and Treatment.
Baird DC, Meyers GJ, Hu JS
Am Fam Physician 2018 Feb 15;97(4):261-268. PMID: 29671528
Paratesticular rhabdomyosarcoma: Importance of initial therapy.
Hammond WJ, Farber BA, Price AP, Wolden SL, Heaton TE, Wexler LH, La Quaglia MP
J Pediatr Surg 2017 Feb;52(2):304-308. Epub 2016 Nov 14 doi: 10.1016/j.jpedsurg.2016.11.027. PMID: 27894767Free PMC Article
Diagnosis and management of spermatic cord tumors.
Moschini M, Mattei A
Curr Opin Urol 2017 Jan;27(1):76-79. doi: 10.1097/MOU.0000000000000318. PMID: 27262142
Lipoblastoma.
Chun YS, Kim WK, Park KW, Lee SC, Jung SE
J Pediatr Surg 2001 Jun;36(6):905-7. doi: 10.1053/jpsu.2001.23969. PMID: 11381423

Diagnosis

Interventional Radiology: Indications and Best Practices.
Arnold MJ, Keung JJ, McCarragher B
Am Fam Physician 2019 May 1;99(9):547-556. PMID: 31038901
Testicular Cancer: Diagnosis and Treatment.
Baird DC, Meyers GJ, Hu JS
Am Fam Physician 2018 Feb 15;97(4):261-268. PMID: 29671528
Diagnosis and management of spermatic cord tumors.
Moschini M, Mattei A
Curr Opin Urol 2017 Jan;27(1):76-79. doi: 10.1097/MOU.0000000000000318. PMID: 27262142
Scrotal tumors.
Armas-Alvarez AL, Salinas-Sánchez AS, Atienzar-Tobarra M, Virseda-Rodríguez JA
Arch Esp Urol 2016 Mar;69(2):86-9. PMID: 26959967
Lymphangioma scroti.
Vikicevic J, Milobratovic D, Vukadinovic V, Golubovic Z, Krstic Z
Pediatr Dermatol 2007 Nov-Dec;24(6):654-6. doi: 10.1111/j.1525-1470.2007.00557.x. PMID: 18035990

Therapy

HPV-related diseases in male patients: an underestimated conundrum.
Garolla A, Graziani A, Grande G, Ortolani C, Ferlin A
J Endocrinol Invest 2024 Feb;47(2):261-274. Epub 2023 Sep 28 doi: 10.1007/s40618-023-02192-3. PMID: 37770654Free PMC Article
Efficacy and safety of HpD-PDT for Extramammary Paget's Disease refractory to conventional therapy: A prospective, open-label and single arm pilot study.
Wang D, Wang P, Li C, Zhou Z, Zhang L, Zhang G, Wang X
Photodiagnosis Photodyn Ther 2022 Mar;37:102670. Epub 2021 Dec 7 doi: 10.1016/j.pdpdt.2021.102670. PMID: 34883272
Extramammary Paget disease.
Hartman R, Chu J, Patel R, Meehan S, Stein JA
Dermatol Online J 2011 Oct 15;17(10):4. PMID: 22031630
Primary genitourinary melanoma.
Nguyen AT, Kavolius JP, Russo P, Grimaldi G, Katz J, Brady MS
Urology 2001 Apr;57(4):633-8. doi: 10.1016/s0090-4295(00)01107-9. PMID: 11306366
Testicular tumors: oncologic imaging and diagnosis.
Heiken JP, Balfe DM, McClennan BL
Int J Radiat Oncol Biol Phys 1984 Feb;10(2):275-87. doi: 10.1016/0360-3016(84)90014-2. PMID: 6200463

Prognosis

Testicular Cancer: Diagnosis and Treatment.
Baird DC, Meyers GJ, Hu JS
Am Fam Physician 2018 Feb 15;97(4):261-268. PMID: 29671528
Scrotal Melanoma: A Systematic Review of Presentation, Treatment, and Outcomes.
Zikry J, Chapman LW, Korta DZ, Smith J
Dermatol Surg 2017 Jun;43(6):765-770. doi: 10.1097/DSS.0000000000001072. PMID: 28291064
Paratesticular rhabdomyosarcoma: Importance of initial therapy.
Hammond WJ, Farber BA, Price AP, Wolden SL, Heaton TE, Wexler LH, La Quaglia MP
J Pediatr Surg 2017 Feb;52(2):304-308. Epub 2016 Nov 14 doi: 10.1016/j.jpedsurg.2016.11.027. PMID: 27894767Free PMC Article
Mammary and extramammary Paget's disease.
Lopes Filho LL, Lopes IM, Lopes LR, Enokihara MM, Michalany AO, Matsunaga N
An Bras Dermatol 2015 Mar-Apr;90(2):225-31. doi: 10.1590/abd1806-4841.20153189. PMID: 25830993Free PMC Article
Primary genitourinary melanoma.
Nguyen AT, Kavolius JP, Russo P, Grimaldi G, Katz J, Brady MS
Urology 2001 Apr;57(4):633-8. doi: 10.1016/s0090-4295(00)01107-9. PMID: 11306366

Clinical prediction guides

Extramammary Paget's Disease of the Scrotal and Penile: A Case Report and Review of the Literature.
Yang X, Lin H, Gao Z, Wang X, Li L, Tian D, Wen Y, Shen J
Urol Int 2024;108(3):264-271. Epub 2024 Feb 17 doi: 10.1159/000536654. PMID: 38368870Free PMC Article
HPV-related diseases in male patients: an underestimated conundrum.
Garolla A, Graziani A, Grande G, Ortolani C, Ferlin A
J Endocrinol Invest 2024 Feb;47(2):261-274. Epub 2023 Sep 28 doi: 10.1007/s40618-023-02192-3. PMID: 37770654Free PMC Article
Clinical characteristics and long-term management of prepubertal testicular teratomas: a retrospective, multicenter study.
Zhou G, Sun F, Yu X, Huang R, Liu X, Ouyang Y, Yang Z, Li S
Eur J Pediatr 2023 Apr;182(4):1823-1828. Epub 2023 Feb 16 doi: 10.1007/s00431-023-04859-8. PMID: 36795187Free PMC Article
Clinical and genetic analysis of idiopathic normophosphatemic tumoral calcinosis in 19 patients.
Zuo QY, Cao X, Liu BY, Yan D, Xin Z, Niu XH, Li C, Deng W, Dong ZY, Yang JK
J Endocrinol Invest 2020 Feb;43(2):173-183. Epub 2019 Sep 18 doi: 10.1007/s40618-019-01097-4. PMID: 31535357
Paratesticular rhabdomyosarcoma: Importance of initial therapy.
Hammond WJ, Farber BA, Price AP, Wolden SL, Heaton TE, Wexler LH, La Quaglia MP
J Pediatr Surg 2017 Feb;52(2):304-308. Epub 2016 Nov 14 doi: 10.1016/j.jpedsurg.2016.11.027. PMID: 27894767Free PMC Article

Recent systematic reviews

Testis-sparing surgery and scrotal violation for testicular masses suspicious for malignancy: A systematic review and meta-analysis.
Patel HD, Gupta M, Cheaib JG, Sharma R, Zhang A, Bass EB, Pierorazio PM
Urol Oncol 2020 May;38(5):344-353. Epub 2020 Mar 17 doi: 10.1016/j.urolonc.2020.02.023. PMID: 32192891
Systematic Review of Surgical Treatment and Outcomes After Local Surgery of Primary Cutaneous Melanomas of the Penis and Scrotum.
Bittar JM, Bittar PG, Wan MT, Kovell RC, Guzzo TJ, Shin TM, Etzkorn JR, Sobanko JF, Miller CJ
Dermatol Surg 2018 Sep;44(9):1159-1169. doi: 10.1097/DSS.0000000000001579. PMID: 29985865
Scrotal Melanoma: A Systematic Review of Presentation, Treatment, and Outcomes.
Zikry J, Chapman LW, Korta DZ, Smith J
Dermatol Surg 2017 Jun;43(6):765-770. doi: 10.1097/DSS.0000000000001072. PMID: 28291064
Adult inguinoscrotal sarcomas: outcome analysis of 21 cases, systematic review of the literature and meta-analysis.
Froehner M, Koch R, Lossnitzer A, Schober RR, Schuler M, Wirth MP
World J Urol 2014 Apr;32(2):445-51. Epub 2013 Jul 9 doi: 10.1007/s00345-013-1124-1. PMID: 23836016

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...