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Low Grade Papillary Schneiderian Carcinoma

MedGen UID:
1792985
•Concept ID:
C5556544
•
Neoplastic Process
Synonyms: Low Grade Papillary Sinonasal Carcinoma; Low-Grade Papillary Schneiderian Carcinoma; Low-Grade Papillary Sinonasal Carcinoma

Definition

A rare sinonasal carcinoma characterized by the presence of a papillary architecture and bland morphological features similar to the Schneiderian papilloma, a pushing pattern of stromal invasion, and an increased risk of local recurrence. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLow Grade Papillary Schneiderian Carcinoma

Recent clinical studies

Etiology

DEK-AFF2 fusion-associated papillary squamous cell carcinoma of the sinonasal tract: clinicopathologic characterization of seven cases with deceptively bland morphology.
Kuo YJ, Lewis JS Jr, Zhai C, Chen YA, Chernock RD, Hsieh MS, Lan MY, Lee CK, Weinreb I, Hang JF
Mod Pathol 2021 Oct;34(10):1820-1830. Epub 2021 Jun 9 doi: 10.1038/s41379-021-00846-2. PMID: 34108636

Diagnosis

Low-grade papillary Schneiderian carcinoma with TP53 mutation: a case report and review of the literature.
Yuzawa S, Michizuka T, Kakisaka R, Ono Y, Hayashi M, Takahara M, Katada A, Mizukami Y, Tanino M
Diagn Pathol 2023 Apr 11;18(1):44. doi: 10.1186/s13000-023-01334-8. PMID: 37041626Free PMC Article
Nasopharyngeal low-grade papillary schneiderian carcinoma with cervical metastasis.
Uraguchi K, Nishida K, Makino T, Makihara S, Tabata M, Kariya S, Ando M
Auris Nasus Larynx 2023 Oct;50(5):821-826. Epub 2022 Dec 28 doi: 10.1016/j.anl.2022.12.010. PMID: 36585284
Clinicopathological analysis of low-grade papillary Schneiderian carcinoma: report of five new cases and review of the literature.
Zhai C, Wang H, Li S, Wang D
Histopathology 2021 Sep;79(3):370-380. Epub 2021 Apr 14 doi: 10.1111/his.14347. PMID: 33539575
Low-Grade Papillary Schneiderian Carcinoma of the Sinonasal Cavity and Temporal Bone.
Brown CS, Abi Hachem R, Pendse A, Madden JF, Francis HW
Ann Otol Rhinol Laryngol 2018 Dec;127(12):974-977. Epub 2018 Sep 29 doi: 10.1177/0003489418803391. PMID: 30269519
Low-Grade Papillary Schneiderian Carcinoma: A Case Report.
Jeong HJ, Roh J, Lee BJ, Cho KJ
Head Neck Pathol 2018 Mar;12(1):131-135. Epub 2017 Jun 21 doi: 10.1007/s12105-017-0832-z. PMID: 28639124Free PMC Article

Prognosis

Nasopharyngeal low-grade papillary schneiderian carcinoma with cervical metastasis.
Uraguchi K, Nishida K, Makino T, Makihara S, Tabata M, Kariya S, Ando M
Auris Nasus Larynx 2023 Oct;50(5):821-826. Epub 2022 Dec 28 doi: 10.1016/j.anl.2022.12.010. PMID: 36585284
DEK-AFF2 fusion-associated papillary squamous cell carcinoma of the sinonasal tract: clinicopathologic characterization of seven cases with deceptively bland morphology.
Kuo YJ, Lewis JS Jr, Zhai C, Chen YA, Chernock RD, Hsieh MS, Lan MY, Lee CK, Weinreb I, Hang JF
Mod Pathol 2021 Oct;34(10):1820-1830. Epub 2021 Jun 9 doi: 10.1038/s41379-021-00846-2. PMID: 34108636
DEK-AFF2 Carcinoma of the Sinonasal Region and Skull Base: Detailed Clinicopathologic Characterization of a Distinctive Entity.
Rooper LM, Agaimy A, Dickson BC, Dueber JC, Eberhart CG, Gagan J, Hartmann A, Khararjian A, London NR, MacMillan CM, Palsgrove DN, Nix JS, Sandison A, Stoehr R, Truong T, Weinreb I, Bishop JA
Am J Surg Pathol 2021 Dec 1;45(12):1682-1693. doi: 10.1097/PAS.0000000000001741. PMID: 34049316
Low-Grade Papillary Schneiderian Carcinoma of the Sinonasal Cavity and Temporal Bone.
Brown CS, Abi Hachem R, Pendse A, Madden JF, Francis HW
Ann Otol Rhinol Laryngol 2018 Dec;127(12):974-977. Epub 2018 Sep 29 doi: 10.1177/0003489418803391. PMID: 30269519
Low-grade papillary schneiderian carcinoma, a unique and deceptively bland malignant neoplasm: report of a case.
Lewis JS Jr, Chernock RD, Haynes W, El-Mofty SK
Am J Surg Pathol 2015 May;39(5):714-21. doi: 10.1097/PAS.0000000000000390. PMID: 25634744

Clinical prediction guides

Clinicopathological analysis of low-grade papillary Schneiderian carcinoma: report of five new cases and review of the literature.
Zhai C, Wang H, Li S, Wang D
Histopathology 2021 Sep;79(3):370-380. Epub 2021 Apr 14 doi: 10.1111/his.14347. PMID: 33539575
Low-Grade Papillary Schneiderian Carcinoma: Report of a Case with Molecular Characterization.
Carnevale S, Ferrario G, Sovardi F, Benazzo M, Morbini P
Head Neck Pathol 2020 Sep;14(3):799-802. Epub 2019 Aug 31 doi: 10.1007/s12105-019-01067-5. PMID: 31473940Free PMC Article

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