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AIDS related complex

MedGen UID:
1793
•Concept ID:
C0001857
•
Disease or Syndrome
Synonyms: AIDS Related Complex; AIDS-Related Complex; ARC; Complex, AIDS-Related; Lymphadenopathy Syndrome; Lymphadenopathy Syndromes; Syndrome, Lymphadenopathy; Syndromes, Lymphadenopathy
 
Monarch Initiative: MONDO:0005639

Definition

A prodromal phase of infection with the human immunodeficiency virus (HIV). Laboratory criteria separating aids-related complex (ARC) from aids include elevated or hyperactive B-cell humoral immune responses, compared to depressed or normal antibody reactivity in aids; follicular or mixed hyperplasia in arc lymph nodes, leading to lymphocyte degeneration and depletion more typical of aids; evolving succession of histopathological lesions such as localization of Kaposi's sarcoma, signaling the transition to the full-blown aids. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAIDS related complex

Professional guidelines

PubMed

Carotenoids in cancer, mastalgia, and AIDS: prevention and treatment--an overview.
Santamaria L, Bianchi-Santamaria A, dell'Orti M
J Environ Pathol Toxicol Oncol 1996;15(2-4):89-95. PMID: 9216791
Zidovudine toxicity. Clinical features and management.
Rachlis A, Fanning MM
Drug Saf 1993 Apr;8(4):312-20. doi: 10.2165/00002018-199308040-00005. PMID: 8481217
Treatment of AIDS and AIDS-related complex with 2',3'-dideoxyinosine given once daily.
Cooley TP, Kunches LM, Saunders CA, Perkins CJ, Kelley SL, McLaren C, McCaffrey RP, Liebman HA
Rev Infect Dis 1990 Jul-Aug;12 Suppl 5:S552-60. doi: 10.1093/clinids/12.supplement_5.s552. PMID: 1974727

Recent clinical studies

Etiology

The changing face of HIV/AIDS in treated patients.
Llibre JM, Falco V, Tural C, Negredo E, Pineda JA, Muñoz J, Ortega E, Videla S, Sirera G, Martinez E, Miralles C, Iribarren J, Galindo MJ, Domingo P, d'Arminio-Monforte A, Miro JM, Clotet B
Curr HIV Res 2009 Jul;7(4):365-77. doi: 10.2174/157016209788680633. PMID: 19601771
AIDS and cerebrovascular disease.
Pinto AN
Stroke 1996 Mar;27(3):538-43. doi: 10.1161/01.str.27.3.538. PMID: 8610326
Pseudomonas infections in patients with AIDS and AIDS-related complex.
Franzetti F, Cernuschi M, Esposito R, Moroni M
J Intern Med 1992 Apr;231(4):437-43. doi: 10.1111/j.1365-2796.1992.tb00957.x. PMID: 1588272
Parotid manifestations of HIV infection.
Zeitlen S, Shaha A
J Surg Oncol 1991 Aug;47(4):230-2. doi: 10.1002/jso.2930470406. PMID: 1861494
Fungal infections in patients with AIDS and AIDS-related complex.
Holmberg K, Meyer RD
Scand J Infect Dis 1986;18(3):179-92. doi: 10.3109/00365548609032326. PMID: 3526530

Diagnosis

Parotid manifestations of HIV infection.
Zeitlen S, Shaha A
J Surg Oncol 1991 Aug;47(4):230-2. doi: 10.1002/jso.2930470406. PMID: 1861494
Electroencephalography in AIDS and AIDS-related complex.
Gabuzda DH, Levy SR, Chiappa KH
Clin Electroencephalogr 1988 Jan;19(1):1-6. doi: 10.1177/155005948801900103. PMID: 3396199
AIDS.
Murphy RL, Phair JP
Compr Ther 1988 Jan;14(1):3-12. PMID: 3277764
AIDS-related lymphadenopathies.
Said JW
Semin Diagn Pathol 1988 Nov;5(4):365-75. PMID: 3064217
Fungal infections in patients with AIDS and AIDS-related complex.
Holmberg K, Meyer RD
Scand J Infect Dis 1986;18(3):179-92. doi: 10.3109/00365548609032326. PMID: 3526530

Therapy

Antiretroviral therapy and immunomodulators in patients with AIDS.
Groopman JE
Am J Med 1991 Apr 10;90(4A):18S-21S. doi: 10.1016/0002-9343(91)90406-n. PMID: 2018046
Zidovudine (Retrovir) update.
Rachlis AR
CMAJ 1990 Dec 1;143(11):1177-85. PMID: 2224694Free PMC Article
Zidovudine intolerance.
Groopman JE
Rev Infect Dis 1990 Jul-Aug;12 Suppl 5:S500-6. doi: 10.1093/clinids/12.supplement_5.s500. PMID: 2201071
Zidovudine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.
Langtry HD, Campoli-Richards DM
Drugs 1989 Apr;37(4):408-50. doi: 10.2165/00003495-198937040-00003. PMID: 2661194
Odynophagia/dysphagia in AIDS.
Raufman JP
Gastroenterol Clin North Am 1988 Sep;17(3):599-614. PMID: 3049365

Prognosis

HIV/AIDS-related hyponatremia: an old but still serious problem.
Shu Z, Tian Z, Chen J, Ma J, Abudureyimu A, Qian Q, Zhuo L
Ren Fail 2018 Nov;40(1):68-74. doi: 10.1080/0886022X.2017.1419975. PMID: 29299949Free PMC Article
AIDS.
Murphy RL, Phair JP
Compr Ther 1988 Jan;14(1):3-12. PMID: 3277764
AIDS-related lymphadenopathies.
Said JW
Semin Diagn Pathol 1988 Nov;5(4):365-75. PMID: 3064217
Clinical manifestations of HIV infections.
Kennedy DH
Scott Med J 1987 Aug;32(4):101-7. doi: 10.1177/003693308703200402. PMID: 3313725
Acquired immune deficiency syndrome: review.
Scully C, Cawson RA, Porter SR
Br Dent J 1986 Jul 19;161(2):53-60. doi: 10.1038/sj.bdj.4805895. PMID: 3524629

Clinical prediction guides

Pathology of AIDS in children.
Joshi VV
Indian J Pediatr 1994 Sep-Oct;61(5):497-512. doi: 10.1007/BF02751710. PMID: 7744451
Parotid manifestations of HIV infection.
Zeitlen S, Shaha A
J Surg Oncol 1991 Aug;47(4):230-2. doi: 10.1002/jso.2930470406. PMID: 1861494
AIDS, Kaposi sarcoma, and the lymphatic system: update and reflections.
Witte MH, Witte CL, Way DL, Fiala M
Lymphology 1990 Jun;23(2):73-80. PMID: 2214866
Pregnancy and AIDS.
Henrion R
Hum Reprod 1988 Feb;3(2):257-62. doi: 10.1093/oxfordjournals.humrep.a136689. PMID: 3281969
AIDS-related lymphadenopathies.
Said JW
Semin Diagn Pathol 1988 Nov;5(4):365-75. PMID: 3064217

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