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Alcohol amnestic disorder

MedGen UID:
1799
•Concept ID:
C0001940
•
Mental or Behavioral Dysfunction
Synonyms: Alcohol Amnestic Disorder; Alcohol Amnestic Disorders; Alcohol Amnestic Syndrome; Alcohol Amnestic Syndromes; Alcohol Induced Amnestic Psychosis; Alcohol Induced Amnestic Syndrome; Alcohol Induced Dysmnesic Psychosis; Alcohol Induced Dysmnesic Syndrome; Alcohol Induced Persisting Amnestic Disorder; Alcohol-Induced Amnestic Psychoses; Alcohol-Induced Amnestic Psychosis; Alcohol-Induced Amnestic Syndrome; Alcohol-Induced Amnestic Syndromes; Alcohol-Induced Dysmnesic Psychoses; Alcohol-Induced Dysmnesic Psychosis; Alcohol-Induced Dysmnesic Syndrome; Alcohol-Induced Dysmnesic Syndromes; Alcohol-Induced Persisting Amnestic Disorder; Amnestic Disorder, Alcohol; Amnestic Psychoses, Alcohol-Induced; Amnestic Psychosis, Alcohol Induced; Amnestic Psychosis, Alcohol-Induced; Amnestic Syndrome, Alcohol-Induced; Amnestic Syndromes, Alcohol-Induced; Dysmnesic Psychoses, Alcohol-Induced; Dysmnesic Psychosis, Alcohol-Induced; Dysmnesic Syndrome, Alcohol-Induced; Dysmnesic Syndromes, Alcohol-Induced; Psychoses, Alcohol-Induced Amnestic; Psychoses, Alcohol-Induced Dysmnesic; Psychosis, Alcohol-Induced Amnestic; Psychosis, Alcohol-Induced Dysmnesic
SNOMED CT: Alcohol amnestic disorder (73097000); Alcohol-induced persisting amnestic disorder (73097000); Korsakov alcoholic psychosis (69482004); Korsakov syndrome - alcoholic (69482004); Amnesic syndrome due to alcohol (69482004); Alcoholic amnestic syndrome (69482004)
 
Monarch Initiative: MONDO:0021702

Definition

A mental disorder associated with chronic ethanol abuse (ALCOHOLISM) and nutritional deficiencies characterized by short term memory loss, confabulations, and disturbances of attention. (Adams et al., Principles of Neurology, 6th ed, p1139) [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAlcohol amnestic disorder

Professional guidelines

PubMed

The Spectrum of Alcohol Use: Epidemiology, Diagnosis, and Treatment.
Cohen SM, Alexander RS, Holt SR
Med Clin North Am 2022 Jan;106(1):43-60. doi: 10.1016/j.mcna.2021.08.003. PMID: 34823734
Apolipoprotein E4 genotype is not associated with short-term cognition deficits during alcohol withdrawal.
Wilhelm J, von Ahsen N, Frieling H, Hillemacher T, Bayerlein K, Bönsch D, Ziegenbein M, Kornhuber J, Bleich S
Alcohol 2005 Nov;37(3):151-6. doi: 10.1016/j.alcohol.2006.01.002. PMID: 16713503
Alcohol withdrawal syndromes: a review of pathophysiology, clinical presentation, and treatment.
Turner RC, Lichstein PR, Peden JG Jr, Busher JT, Waivers LE
J Gen Intern Med 1989 Sep-Oct;4(5):432-44. doi: 10.1007/BF02599697. PMID: 2677272

Recent clinical studies

Etiology

Pharmacological enhancing agents targeting cognition in patients with alcohol-induced neurocognitive disorders: A systematic review.
Mistarz N, Andersen K, Nielsen AS, Goudriaan AE, Michel TM, Skøt L, Nielsen DG, Mellentin AI
Neurosci Biobehav Rev 2021 Jun;125:608-626. Epub 2021 Mar 2 doi: 10.1016/j.neubiorev.2021.02.038. PMID: 33667552
Preventing and diagnosing dementia.
Keenan B, Jenkins C, Ginesi L
Nurs Times 2016 Jun 29-Jul 5;112(26):22-5. PMID: 27544960
Alcoholic metabolic emergencies.
Allison MG, McCurdy MT
Emerg Med Clin North Am 2014 May;32(2):293-301. Epub 2014 Feb 19 doi: 10.1016/j.emc.2013.12.002. PMID: 24766933
Alcohol dependence: a critical look at the effects of alcohol metabolism.
Anyanwu E, Watson N
Rev Environ Health 1997 Jul-Sep;12(3):201-13. doi: 10.1515/reveh.1997.12.3.201. PMID: 9406291
Neuropathology of alcoholism.
Harper CG, Kril JJ
Alcohol Alcohol 1990;25(2-3):207-16. doi: 10.1093/oxfordjournals.alcalc.a044994. PMID: 2198036

Diagnosis

Preventing and diagnosing dementia.
Keenan B, Jenkins C, Ginesi L
Nurs Times 2016 Jun 29-Jul 5;112(26):22-5. PMID: 27544960
Alcohol amnesia.
Goodwin DW
Addiction 1995 Mar;90(3):315-7. doi: 10.1111/j.1360-0443.1995.tb03779.x. PMID: 7735016
Wernicke's encephalopathy.
Lindberg MC, Oyler RA
Am Fam Physician 1990 Apr;41(4):1205-9. PMID: 2181837
Alcohol and the brain.
Lishman WA
Br J Psychiatry 1990 May;156:635-44. doi: 10.1192/bjp.156.5.635. PMID: 2099160
Amnesia.
Benson DF
South Med J 1978 Oct;71(10):1221-7, 1231. doi: 10.1097/00007611-197810000-00011. PMID: 360401

Therapy

Wernicke-Korsakoff syndrome.
Zubaran C, Fernandes JG, Rodnight R
Postgrad Med J 1997 Jan;73(855):27-31. doi: 10.1136/pgmj.73.855.27. PMID: 9039406Free PMC Article
Wernicke's encephalopathy.
Lindberg MC, Oyler RA
Am Fam Physician 1990 Apr;41(4):1205-9. PMID: 2181837
Korsakoff's syndrome.
Lancet 1990 Oct 13;336(8720):912-3. PMID: 1976934
Clonidine.
Roehrich H, Gold MS
Adv Alcohol Subst Abuse 1987;7(1):1-16. doi: 10.1300/j251v07n01_01. PMID: 3327371
Amnesia.
Benson DF
South Med J 1978 Oct;71(10):1221-7, 1231. doi: 10.1097/00007611-197810000-00011. PMID: 360401

Prognosis

Alcoholic metabolic emergencies.
Allison MG, McCurdy MT
Emerg Med Clin North Am 2014 May;32(2):293-301. Epub 2014 Feb 19 doi: 10.1016/j.emc.2013.12.002. PMID: 24766933
Wernicke-Korsakoff encephalopathy.
Pearce JM
Eur Neurol 2008;59(1-2):101-4. Epub 2007 Oct 11 doi: 10.1159/000109580. PMID: 17934284
Wernicke-Korsakoff syndrome.
Zubaran C, Fernandes JG, Rodnight R
Postgrad Med J 1997 Jan;73(855):27-31. doi: 10.1136/pgmj.73.855.27. PMID: 9039406Free PMC Article
Alcoholism and dementia.
Smith DM, Atkinson RM
Int J Addict 1995 Nov-Dec;30(13-14):1843-69. doi: 10.3109/10826089509071058. PMID: 8751321
Specificity of memory deficits in alcoholism.
Riege WH
Recent Dev Alcohol 1987;5:81-109. doi: 10.1007/978-1-4899-1684-6_4. PMID: 3550919

Clinical prediction guides

Rewriting the valuation and salience of alcohol-related stimuli via memory reconsolidation.
Das RK, Lawn W, Kamboj SK
Transl Psychiatry 2015 Sep 22;5(9):e645. doi: 10.1038/tp.2015.132. PMID: 26393491Free PMC Article
Thalamic abnormalities are a cardinal feature of alcohol-related brain dysfunction.
Pitel AL, Segobin SH, Ritz L, Eustache F, Beaunieux H
Neurosci Biobehav Rev 2015 Jul;54:38-45. Epub 2014 Aug 6 doi: 10.1016/j.neubiorev.2014.07.023. PMID: 25108034
Clinical and physiological implications and correlations.
Berglund M
Alcohol Alcohol Suppl 1991;1:399-402. PMID: 1845570
Specificity of memory deficits in alcoholism.
Riege WH
Recent Dev Alcohol 1987;5:81-109. doi: 10.1007/978-1-4899-1684-6_4. PMID: 3550919
The neuroanatomy of amnesia. A critique of the hippocampal memory hypothesis.
Horel JA
Brain 1978 Sep;101(3):403-45. doi: 10.1093/brain/101.3.403. PMID: 101278

Recent systematic reviews

Pharmacological enhancing agents targeting cognition in patients with alcohol-induced neurocognitive disorders: A systematic review.
Mistarz N, Andersen K, Nielsen AS, Goudriaan AE, Michel TM, Skøt L, Nielsen DG, Mellentin AI
Neurosci Biobehav Rev 2021 Jun;125:608-626. Epub 2021 Mar 2 doi: 10.1016/j.neubiorev.2021.02.038. PMID: 33667552
Health problems and care needs in patients with Korsakoff's syndrome: A systematic review.
van Dam MJ, van Meijel B, Postma A, Oudman E
J Psychiatr Ment Health Nurs 2020 Aug;27(4):460-481. Epub 2020 Jan 15 doi: 10.1111/jpm.12587. PMID: 31876326
Alcohol consumption as a risk factor for dementia and cognitive decline: meta-analysis of prospective studies.
Anstey KJ, Mack HA, Cherbuin N
Am J Geriatr Psychiatry 2009 Jul;17(7):542-55. doi: 10.1097/JGP.0b013e3181a2fd07. PMID: 19546653

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