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Extremely preterm birth

MedGen UID:
1813081
Concept ID:
C5676607
Finding
HPO: HP:0025665

Definition

Birth before 28 completed weeks of gestation (up to and including 27 weeks and 6 days of gestation). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVExtremely preterm birth

Professional guidelines

PubMed

Helou YE, Buhimschi IA, Romano-Keeler J, Buhimschi CS
Semin Perinatol 2022 Feb;46(1):151539. Epub 2021 Nov 10 doi: 10.1016/j.semperi.2021.151539. PMID: 34887106
Heo JS, Ahn KH, Park JS
Sci Rep 2020 Dec 4;10(1):21266. doi: 10.1038/s41598-020-78385-0. PMID: 33277556Free PMC Article
Janvier A, Barrington KJ, Payot A
Arch Dis Child Fetal Neonatal Ed 2020 May;105(3):230-231. Epub 2020 Mar 10 doi: 10.1136/archdischild-2019-318553. PMID: 32156712

Recent clinical studies

Etiology

Ninan K, Liyanage SK, Murphy KE, Asztalos EV, McDonald SD
JAMA Pediatr 2022 Jun 1;176(6):e220483. Epub 2022 Jun 6 doi: 10.1001/jamapediatrics.2022.0483. PMID: 35404395Free PMC Article
Hellström A, Nilsson AK, Wackernagel D, Pivodic A, Vanpee M, Sjöbom U, Hellgren G, Hallberg B, Domellöf M, Klevebro S, Hellström W, Andersson M, Lund AM, Löfqvist C, Elfvin A, Sävman K, Hansen-Pupp I, Hård AL, Smith LEH, Ley D
JAMA Pediatr 2021 Apr 1;175(4):359-367. doi: 10.1001/jamapediatrics.2020.5653. PMID: 33523106Free PMC Article
Ophelders DRMG, Gussenhoven R, Klein L, Jellema RK, Westerlaken RJJ, Hütten MC, Vermeulen J, Wassink G, Gunn AJ, Wolfs TGAM
Cells 2020 Aug 10;9(8) doi: 10.3390/cells9081871. PMID: 32785181Free PMC Article
Rogers EE, Hintz SR
Semin Perinatol 2016 Dec;40(8):497-509. Epub 2016 Nov 16 doi: 10.1053/j.semperi.2016.09.002. PMID: 27865437
Stoll BJ, Hansen NI, Bell EF, Walsh MC, Carlo WA, Shankaran S, Laptook AR, Sánchez PJ, Van Meurs KP, Wyckoff M, Das A, Hale EC, Ball MB, Newman NS, Schibler K, Poindexter BB, Kennedy KA, Cotten CM, Watterberg KL, D'Angio CT, DeMauro SB, Truog WE, Devaskar U, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
JAMA 2015 Sep 8;314(10):1039-51. doi: 10.1001/jama.2015.10244. PMID: 26348753Free PMC Article

Diagnosis

Boyd SM, Tapawan SJ, Badawi N, Popat H
Semin Fetal Neonatal Med 2022 Jun;27(3):101370. Epub 2022 Jun 18 doi: 10.1016/j.siny.2022.101370. PMID: 35752599
O'Reilly H, Ni Y, Johnson S, Wolke D, Marlow N
Mol Autism 2021 May 6;12(1):30. doi: 10.1186/s13229-021-00414-0. PMID: 33957985Free PMC Article
Valgeirsdottir H, Sundström Poromaa I, Kunovac Kallak T, Vanky E, Akhter T, Roos N, Stephansson O, Wikström AK
PLoS One 2021;16(2):e0246743. Epub 2021 Feb 4 doi: 10.1371/journal.pone.0246743. PMID: 33539479Free PMC Article
Hellström A, Nilsson AK, Wackernagel D, Pivodic A, Vanpee M, Sjöbom U, Hellgren G, Hallberg B, Domellöf M, Klevebro S, Hellström W, Andersson M, Lund AM, Löfqvist C, Elfvin A, Sävman K, Hansen-Pupp I, Hård AL, Smith LEH, Ley D
JAMA Pediatr 2021 Apr 1;175(4):359-367. doi: 10.1001/jamapediatrics.2020.5653. PMID: 33523106Free PMC Article
Johnson S, Marlow N
Semin Fetal Neonatal Med 2014 Apr;19(2):97-104. Epub 2013 Dec 2 doi: 10.1016/j.siny.2013.11.004. PMID: 24290907

Therapy

Ninan K, Liyanage SK, Murphy KE, Asztalos EV, McDonald SD
JAMA Pediatr 2022 Jun 1;176(6):e220483. Epub 2022 Jun 6 doi: 10.1001/jamapediatrics.2022.0483. PMID: 35404395Free PMC Article
Watterberg KL, Walsh MC, Li L, Chawla S, D'Angio CT, Goldberg RN, Hintz SR, Laughon MM, Yoder BA, Kennedy KA, McDavid GE, Backstrom-Lacy C, Das A, Crawford MM, Keszler M, Sokol GM, Poindexter BB, Ambalavanan N, Hibbs AM, Truog WE, Schmidt B, Wyckoff MH, Khan AM, Garg M, Chess PR, Reynolds AM, Moallem M, Bell EF, Meyer LR, Patel RM, Van Meurs KP, Cotten CM, McGowan EC, Hines AC, Merhar S, Peralta-Carcelen M, Wilson-Costello DE, Kilbride HW, DeMauro SB, Heyne RJ, Mosquera RA, Natarajan G, Purdy IB, Lowe JR, Maitre NL, Harmon HM, Hogden LA, Adams-Chapman I, Winter S, Malcolm WF, Higgins RD; Eunice Kennedy Shriver NICHD Neonatal Research Network
N Engl J Med 2022 Mar 24;386(12):1121-1131. doi: 10.1056/NEJMoa2114897. PMID: 35320643Free PMC Article
Rysavy MA, Mehler K, Oberthür A, Ågren J, Kusuda S, McNamara PJ, Giesinger RE, Kribs A, Normann E, Carlson SJ, Klein JM, Backes CH, Bell EF
J Pediatr 2021 Jun;233:16-25.e1. Epub 2021 Mar 7 doi: 10.1016/j.jpeds.2021.03.006. PMID: 33691163Free PMC Article
Hellström A, Nilsson AK, Wackernagel D, Pivodic A, Vanpee M, Sjöbom U, Hellgren G, Hallberg B, Domellöf M, Klevebro S, Hellström W, Andersson M, Lund AM, Löfqvist C, Elfvin A, Sävman K, Hansen-Pupp I, Hård AL, Smith LEH, Ley D
JAMA Pediatr 2021 Apr 1;175(4):359-367. doi: 10.1001/jamapediatrics.2020.5653. PMID: 33523106Free PMC Article
Stoll BJ, Hansen NI, Bell EF, Walsh MC, Carlo WA, Shankaran S, Laptook AR, Sánchez PJ, Van Meurs KP, Wyckoff M, Das A, Hale EC, Ball MB, Newman NS, Schibler K, Poindexter BB, Kennedy KA, Cotten CM, Watterberg KL, D'Angio CT, DeMauro SB, Truog WE, Devaskar U, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
JAMA 2015 Sep 8;314(10):1039-51. doi: 10.1001/jama.2015.10244. PMID: 26348753Free PMC Article

Prognosis

Ninan K, Liyanage SK, Murphy KE, Asztalos EV, McDonald SD
JAMA Pediatr 2022 Jun 1;176(6):e220483. Epub 2022 Jun 6 doi: 10.1001/jamapediatrics.2022.0483. PMID: 35404395Free PMC Article
Watterberg KL, Walsh MC, Li L, Chawla S, D'Angio CT, Goldberg RN, Hintz SR, Laughon MM, Yoder BA, Kennedy KA, McDavid GE, Backstrom-Lacy C, Das A, Crawford MM, Keszler M, Sokol GM, Poindexter BB, Ambalavanan N, Hibbs AM, Truog WE, Schmidt B, Wyckoff MH, Khan AM, Garg M, Chess PR, Reynolds AM, Moallem M, Bell EF, Meyer LR, Patel RM, Van Meurs KP, Cotten CM, McGowan EC, Hines AC, Merhar S, Peralta-Carcelen M, Wilson-Costello DE, Kilbride HW, DeMauro SB, Heyne RJ, Mosquera RA, Natarajan G, Purdy IB, Lowe JR, Maitre NL, Harmon HM, Hogden LA, Adams-Chapman I, Winter S, Malcolm WF, Higgins RD; Eunice Kennedy Shriver NICHD Neonatal Research Network
N Engl J Med 2022 Mar 24;386(12):1121-1131. doi: 10.1056/NEJMoa2114897. PMID: 35320643Free PMC Article
Bell EF, Hintz SR, Hansen NI, Bann CM, Wyckoff MH, DeMauro SB, Walsh MC, Vohr BR, Stoll BJ, Carlo WA, Van Meurs KP, Rysavy MA, Patel RM, Merhar SL, Sánchez PJ, Laptook AR, Hibbs AM, Cotten CM, D'Angio CT, Winter S, Fuller J, Das A; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
JAMA 2022 Jan 18;327(3):248-263. doi: 10.1001/jama.2021.23580. PMID: 35040888Free PMC Article
Ophelders DRMG, Gussenhoven R, Klein L, Jellema RK, Westerlaken RJJ, Hütten MC, Vermeulen J, Wassink G, Gunn AJ, Wolfs TGAM
Cells 2020 Aug 10;9(8) doi: 10.3390/cells9081871. PMID: 32785181Free PMC Article
Rogers EE, Hintz SR
Semin Perinatol 2016 Dec;40(8):497-509. Epub 2016 Nov 16 doi: 10.1053/j.semperi.2016.09.002. PMID: 27865437

Clinical prediction guides

Stoye DQ, Boardman JP, Osmond C, Sullivan G, Lamb G, Black GS, Homer NZ, Nelson N, Theodorsson E, Reynolds RM, Mörelius E
Arch Dis Child Fetal Neonatal Ed 2022 Sep;107(5):565-567. Epub 2022 Mar 14 doi: 10.1136/archdischild-2021-323296. PMID: 35288450
Hviid A, Laksafoss A, Hedley P, Lausten-Thomsen U, Hjalgrim H, Christiansen M, Olsen SF
JAMA Netw Open 2022 Feb 1;5(2):e2145800. doi: 10.1001/jamanetworkopen.2021.45800. PMID: 35113166Free PMC Article
Prior E, Modi N
Postgrad Med J 2020 Oct;96(1140):619-622. Epub 2020 Aug 11 doi: 10.1136/postgradmedj-2020-137707. PMID: 32788314
Cheong JL, Spittle AJ, Burnett AC, Anderson PJ, Doyle LW
Semin Fetal Neonatal Med 2020 Jun;25(3):101114. Epub 2020 May 15 doi: 10.1016/j.siny.2020.101114. PMID: 32451304
Stoll BJ, Hansen NI, Bell EF, Walsh MC, Carlo WA, Shankaran S, Laptook AR, Sánchez PJ, Van Meurs KP, Wyckoff M, Das A, Hale EC, Ball MB, Newman NS, Schibler K, Poindexter BB, Kennedy KA, Cotten CM, Watterberg KL, D'Angio CT, DeMauro SB, Truog WE, Devaskar U, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network
JAMA 2015 Sep 8;314(10):1039-51. doi: 10.1001/jama.2015.10244. PMID: 26348753Free PMC Article

Recent systematic reviews

Behboudi-Gandevani S, Bidhendi-Yarandi R, Hossein Panahi M, Mardani A, Prinds C, Vaismoradi M, Glarcher M
J Int Med Res 2023 Oct;51(10):3000605231203843. doi: 10.1177/03000605231203843. PMID: 37843530Free PMC Article
Ninan K, Liyanage SK, Murphy KE, Asztalos EV, McDonald SD
JAMA Pediatr 2022 Jun 1;176(6):e220483. Epub 2022 Jun 6 doi: 10.1001/jamapediatrics.2022.0483. PMID: 35404395Free PMC Article
Tanaka K, Tanaka S, Shah N, Ota E, Namba F
J Matern Fetal Neonatal Med 2022 May;35(9):1730-1738. Epub 2020 May 27 doi: 10.1080/14767058.2020.1769590. PMID: 32456494
Blanc J, Rességuier N, Loundou A, Boyer L, Auquier P, Tosello B, d'Ercole C
Eur J Obstet Gynecol Reprod Biol 2021 Jun;261:116-123. Epub 2021 Apr 21 doi: 10.1016/j.ejogrb.2021.04.022. PMID: 33932682
Crump C
J Perinatol 2020 Jun;40(6):833-843. Epub 2019 Nov 25 doi: 10.1038/s41372-019-0563-y. PMID: 31767981Free PMC Article

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