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Anti-tyrosyl-tRNA synthetase antibody positivity

MedGen UID:
1814315
Concept ID:
C5676746
Finding
Synonym: Anti-Ha antibody positivity
 
HPO: HP:0034150

Definition

The presence of autoantibodies (immunoglobulins) in the blood circulation that react against tyrosyl-tRNA synthetase. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnti-tyrosyl-tRNA synthetase antibody positivity

Professional guidelines

PubMed

Teel A, Lu J, Park J, Singh N, Basharat P
Semin Arthritis Rheum 2022 Dec;57:152088. Epub 2022 Aug 31 doi: 10.1016/j.semarthrit.2022.152088. PMID: 36116345
Fujisawa T
Medicina (Kaunas) 2021 Apr 3;57(4) doi: 10.3390/medicina57040347. PMID: 33916864Free PMC Article
Fasano S, Gordon P, Hajji R, Loyo E, Isenberg DA
Rheumatology (Oxford) 2017 Jan;56(1):26-36. Epub 2016 Apr 27 doi: 10.1093/rheumatology/kew146. PMID: 27121778

Recent clinical studies

Etiology

Teel A, Lu J, Park J, Singh N, Basharat P
Semin Arthritis Rheum 2022 Dec;57:152088. Epub 2022 Aug 31 doi: 10.1016/j.semarthrit.2022.152088. PMID: 36116345
Zuo Y, Ye L, Chen F, Shen Y, Lu X, Wang G, Shu X
Front Immunol 2022;13:845988. Epub 2022 Mar 7 doi: 10.3389/fimmu.2022.845988. PMID: 35320936Free PMC Article
Zanframundo G, Faghihi-Kashani S, Scirè CA, Bonella F, Corte TJ, Doyle TJ, Fiorentino D, Gonzalez-Gay MA, Hudson M, Kuwana M, Lundberg IE, Mammen A, McHugh N, Miller FW, Monteccucco C, Oddis CV, Rojas-Serrano J, Schmidt J, Selva-O'Callaghan A, Werth VP, Sakellariou G, Aggarwal R, Cavagna L
Clin Exp Rheumatol 2022 Feb;40(2):309-319. Epub 2022 Feb 25 doi: 10.55563/clinexprheumatol/8xj0b9. PMID: 35225224Free PMC Article
Fujisawa T
Medicina (Kaunas) 2021 Apr 3;57(4) doi: 10.3390/medicina57040347. PMID: 33916864Free PMC Article
Yang Y, Gao X, Zhang M, Yan S, Sun C, Xiao F, Huang N, Yang X, Zhao K, Zhou H, Huang S, Xie B, Zhang N
J Natl Cancer Inst 2018 Mar 1;110(3):304-15. doi: 10.1093/jnci/djx166. PMID: 28903484Free PMC Article

Diagnosis

Zanframundo G, Faghihi-Kashani S, Scirè CA, Bonella F, Corte TJ, Doyle TJ, Fiorentino D, Gonzalez-Gay MA, Hudson M, Kuwana M, Lundberg IE, Mammen A, McHugh N, Miller FW, Monteccucco C, Oddis CV, Rojas-Serrano J, Schmidt J, Selva-O'Callaghan A, Werth VP, Sakellariou G, Aggarwal R, Cavagna L
Clin Exp Rheumatol 2022 Feb;40(2):309-319. Epub 2022 Feb 25 doi: 10.55563/clinexprheumatol/8xj0b9. PMID: 35225224Free PMC Article
Tong Y, Guo D, Lin SH, Liang J, Yang D, Ma C, Shao F, Li M, Yu Q, Jiang Y, Li L, Fang J, Yu R, Lu Z
Mol Cell 2021 Jun 3;81(11):2303-2316.e8. Epub 2021 May 14 doi: 10.1016/j.molcel.2021.04.002. PMID: 33991485
Riddell V, Bagby S, McHugh N
Curr Opin Rheumatol 2020 Nov;32(6):548-552. doi: 10.1097/BOR.0000000000000742. PMID: 32890028
Yang Y, Gao X, Zhang M, Yan S, Sun C, Xiao F, Huang N, Yang X, Zhao K, Zhou H, Huang S, Xie B, Zhang N
J Natl Cancer Inst 2018 Mar 1;110(3):304-15. doi: 10.1093/jnci/djx166. PMID: 28903484Free PMC Article
Satoh M, Tanaka S, Ceribelli A, Calise SJ, Chan EK
Clin Rev Allergy Immunol 2017 Feb;52(1):1-19. doi: 10.1007/s12016-015-8510-y. PMID: 26424665Free PMC Article

Therapy

Teel A, Lu J, Park J, Singh N, Basharat P
Semin Arthritis Rheum 2022 Dec;57:152088. Epub 2022 Aug 31 doi: 10.1016/j.semarthrit.2022.152088. PMID: 36116345
Egashira R
Medicina (Kaunas) 2021 Jul 6;57(7) doi: 10.3390/medicina57070692. PMID: 34356972Free PMC Article
Pham TC, Jayasinghe MK, Pham TT, Yang Y, Wei L, Usman WM, Chen H, Pirisinu M, Gong J, Kim S, Peng B, Wang W, Chan C, Ma V, Nguyen NTH, Kappei D, Nguyen XH, Cho WC, Shi J, Le MTN
J Extracell Vesicles 2021 Feb;10(4):e12057. Epub 2021 Feb 16 doi: 10.1002/jev2.12057. PMID: 33643546Free PMC Article
Braun DA, Hou Y, Bakouny Z, Ficial M, Sant' Angelo M, Forman J, Ross-Macdonald P, Berger AC, Jegede OA, Elagina L, Steinharter J, Sun M, Wind-Rotolo M, Pignon JC, Cherniack AD, Lichtenstein L, Neuberg D, Catalano P, Freeman GJ, Sharpe AH, McDermott DF, Van Allen EM, Signoretti S, Wu CJ, Shukla SA, Choueiri TK
Nat Med 2020 Jun;26(6):909-918. Epub 2020 May 29 doi: 10.1038/s41591-020-0839-y. PMID: 32472114Free PMC Article
Shioya S, Masuda T, Yamaguchi K, Sakamoto S, Horimasu Y, Nakashima T, Miyamoto S, Senoo T, Iwamoto H, Ohshimo S, Fujitaka K, Hamada H, Hattori N
Respir Med 2019 Jun;152:44-50. Epub 2019 May 1 doi: 10.1016/j.rmed.2019.04.023. PMID: 31128609

Prognosis

Zuo Y, Ye L, Chen F, Shen Y, Lu X, Wang G, Shu X
Front Immunol 2022;13:845988. Epub 2022 Mar 7 doi: 10.3389/fimmu.2022.845988. PMID: 35320936Free PMC Article
Tong Y, Guo D, Lin SH, Liang J, Yang D, Ma C, Shao F, Li M, Yu Q, Jiang Y, Li L, Fang J, Yu R, Lu Z
Mol Cell 2021 Jun 3;81(11):2303-2316.e8. Epub 2021 May 14 doi: 10.1016/j.molcel.2021.04.002. PMID: 33991485
Fujisawa T
Medicina (Kaunas) 2021 Apr 3;57(4) doi: 10.3390/medicina57040347. PMID: 33916864Free PMC Article
Braun DA, Hou Y, Bakouny Z, Ficial M, Sant' Angelo M, Forman J, Ross-Macdonald P, Berger AC, Jegede OA, Elagina L, Steinharter J, Sun M, Wind-Rotolo M, Pignon JC, Cherniack AD, Lichtenstein L, Neuberg D, Catalano P, Freeman GJ, Sharpe AH, McDermott DF, Van Allen EM, Signoretti S, Wu CJ, Shukla SA, Choueiri TK
Nat Med 2020 Jun;26(6):909-918. Epub 2020 May 29 doi: 10.1038/s41591-020-0839-y. PMID: 32472114Free PMC Article
Satoh M, Tanaka S, Ceribelli A, Calise SJ, Chan EK
Clin Rev Allergy Immunol 2017 Feb;52(1):1-19. doi: 10.1007/s12016-015-8510-y. PMID: 26424665Free PMC Article

Clinical prediction guides

Zuo Y, Ye L, Chen F, Shen Y, Lu X, Wang G, Shu X
Front Immunol 2022;13:845988. Epub 2022 Mar 7 doi: 10.3389/fimmu.2022.845988. PMID: 35320936Free PMC Article
Wilfong EM, Young-Glazer JJ, Sohn BK, Schroeder G, Annapureddy N, Gillaspie EA, Barnado A, Crofford LJ, Dudenhofer RB
Respir Med 2022 Jan;191:106432. Epub 2021 May 4 doi: 10.1016/j.rmed.2021.106432. PMID: 33994288Free PMC Article
Fujisawa T
Medicina (Kaunas) 2021 Apr 3;57(4) doi: 10.3390/medicina57040347. PMID: 33916864Free PMC Article
Fukui S, Kobayashi K, Fujita Y, Fukui S, Iwamoto N, Adachi T, Hidaka M, Takatsuki M, Abe K, Kuwana M, Kawakami A, Eguchi S
Intern Med 2020 Aug 15;59(16):2071-2076. Epub 2020 May 23 doi: 10.2169/internalmedicine.3923-19. PMID: 32448829Free PMC Article
Satoh M, Tanaka S, Ceribelli A, Calise SJ, Chan EK
Clin Rev Allergy Immunol 2017 Feb;52(1):1-19. doi: 10.1007/s12016-015-8510-y. PMID: 26424665Free PMC Article

Recent systematic reviews

Hannah JR, Law HE, Gordon T, Rooney M, Buazon A, Adas M, Nagra D, Stovin C, Galloway J, Gordon PA
J Rheumatol 2023 Mar;50(3):373-383. Epub 2022 Sep 1 doi: 10.3899/jrheum.220383. PMID: 36379584
Teel A, Lu J, Park J, Singh N, Basharat P
Semin Arthritis Rheum 2022 Dec;57:152088. Epub 2022 Aug 31 doi: 10.1016/j.semarthrit.2022.152088. PMID: 36116345
Zanframundo G, Faghihi-Kashani S, Scirè CA, Bonella F, Corte TJ, Doyle TJ, Fiorentino D, Gonzalez-Gay MA, Hudson M, Kuwana M, Lundberg IE, Mammen A, McHugh N, Miller FW, Monteccucco C, Oddis CV, Rojas-Serrano J, Schmidt J, Selva-O'Callaghan A, Werth VP, Sakellariou G, Aggarwal R, Cavagna L
Clin Exp Rheumatol 2022 Feb;40(2):309-319. Epub 2022 Feb 25 doi: 10.55563/clinexprheumatol/8xj0b9. PMID: 35225224Free PMC Article

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