U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Fixated interest with abnormal focus

MedGen UID:
1814420
Concept ID:
C5676857
Mental or Behavioral Dysfunction
Synonym: Unusual preoccupations
 
HPO: HP:4000077

Definition

A fixated interest in a specific topic that is atypical for the social context of the individual, such as topics of a non-social nature like fossils or vacuum cleaners. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFixated interest with abnormal focus

Professional guidelines

PubMed

Yoshitani J, Schoyer B, Shah A, Khanduja V
Int Orthop 2024 Mar;48(3):657-666. Epub 2024 Jan 10 doi: 10.1007/s00264-023-06078-0. PMID: 38195946Free PMC Article

Recent clinical studies

Etiology

Kamal M, Möbius M, Bartella AK, Lethaus B
J Craniomaxillofac Surg 2023 Nov;51(11):708-715. Epub 2023 Oct 4 doi: 10.1016/j.jcms.2023.09.009. PMID: 37813772
Anand S, Singh A, Bajpai M
J Pediatr Urol 2021 Apr;17(2):183-189. Epub 2020 Dec 19 doi: 10.1016/j.jpurol.2020.12.012. PMID: 33478901
Martínez-Aznar C, Parada-Avendaño I, Gómez-Palacio VE, Abando-Ruiz S, Gil-Albarova J
Jt Dis Relat Surg 2021;32(1):224-229. Epub 2021 Jan 6 doi: 10.5606/ehc.2021.79576. PMID: 33463441Free PMC Article
Smyrnakis I, Andreadakis V, Selimis V, Kalaitzakis M, Bachourou T, Kaloutsakis G, Kymionis GD, Smirnakis S, Aslanides IM
PLoS One 2017;12(8):e0182597. Epub 2017 Aug 11 doi: 10.1371/journal.pone.0182597. PMID: 28800632Free PMC Article
Zwaigenbaum L, Bryson S, Rogers T, Roberts W, Brian J, Szatmari P
Int J Dev Neurosci 2005 Apr-May;23(2-3):143-52. doi: 10.1016/j.ijdevneu.2004.05.001. PMID: 15749241

Diagnosis

Yoshitani J, Schoyer B, Shah A, Khanduja V
Int Orthop 2024 Mar;48(3):657-666. Epub 2024 Jan 10 doi: 10.1007/s00264-023-06078-0. PMID: 38195946Free PMC Article
Jannelli G, Moiraghi A, Paun L, Tessitore E, Dayer R, Bartoli A
Childs Nerv Syst 2022 May;38(5):991-995. Epub 2022 Mar 16 doi: 10.1007/s00381-022-05495-7. PMID: 35296931Free PMC Article
Nelson JL, Blume GM, Bansal SK, Kaufman JR, Woods FR, Zhang X, Kattah JC
J Neuroophthalmol 2022 Jun 1;42(2):251-255. Epub 2021 Dec 30 doi: 10.1097/WNO.0000000000001498. PMID: 34974489
Martínez-Aznar C, Parada-Avendaño I, Gómez-Palacio VE, Abando-Ruiz S, Gil-Albarova J
Jt Dis Relat Surg 2021;32(1):224-229. Epub 2021 Jan 6 doi: 10.5606/ehc.2021.79576. PMID: 33463441Free PMC Article
Smyrnakis I, Andreadakis V, Selimis V, Kalaitzakis M, Bachourou T, Kaloutsakis G, Kymionis GD, Smirnakis S, Aslanides IM
PLoS One 2017;12(8):e0182597. Epub 2017 Aug 11 doi: 10.1371/journal.pone.0182597. PMID: 28800632Free PMC Article

Therapy

Kamal M, Möbius M, Bartella AK, Lethaus B
J Craniomaxillofac Surg 2023 Nov;51(11):708-715. Epub 2023 Oct 4 doi: 10.1016/j.jcms.2023.09.009. PMID: 37813772
Nelson JL, Blume GM, Bansal SK, Kaufman JR, Woods FR, Zhang X, Kattah JC
J Neuroophthalmol 2022 Jun 1;42(2):251-255. Epub 2021 Dec 30 doi: 10.1097/WNO.0000000000001498. PMID: 34974489
Burstein O, Zevin Z, Geva R
JAMA Netw Open 2021 Mar 1;4(3):e213687. doi: 10.1001/jamanetworkopen.2021.3687. PMID: 33783515Free PMC Article
Belmonte MK, Yurgelun-Todd DA
Brain Res Cogn Brain Res 2003 Oct;17(3):651-64. doi: 10.1016/s0926-6410(03)00189-7. PMID: 14561452

Prognosis

Neves J, Hsieh C, Nobre IB, Sousa SC, Ouyang C, Maciel A, Duchowski A, Jorge J, Moreira C
Eur J Radiol 2024 Mar;172:111341. Epub 2024 Feb 1 doi: 10.1016/j.ejrad.2024.111341. PMID: 38340426
Kamal M, Möbius M, Bartella AK, Lethaus B
J Craniomaxillofac Surg 2023 Nov;51(11):708-715. Epub 2023 Oct 4 doi: 10.1016/j.jcms.2023.09.009. PMID: 37813772
D'Souza D, D'Souza H, Johnson MH, Karmiloff-Smith A
PLoS One 2015;10(10):e0139319. Epub 2015 Oct 1 doi: 10.1371/journal.pone.0139319. PMID: 26426329Free PMC Article
Zwaigenbaum L, Bryson S, Rogers T, Roberts W, Brian J, Szatmari P
Int J Dev Neurosci 2005 Apr-May;23(2-3):143-52. doi: 10.1016/j.ijdevneu.2004.05.001. PMID: 15749241
Klin A, Jones W, Schultz R, Volkmar F, Cohen D
Arch Gen Psychiatry 2002 Sep;59(9):809-16. doi: 10.1001/archpsyc.59.9.809. PMID: 12215080

Clinical prediction guides

Yoshitani J, Schoyer B, Shah A, Khanduja V
Int Orthop 2024 Mar;48(3):657-666. Epub 2024 Jan 10 doi: 10.1007/s00264-023-06078-0. PMID: 38195946Free PMC Article
Kamal M, Möbius M, Bartella AK, Lethaus B
J Craniomaxillofac Surg 2023 Nov;51(11):708-715. Epub 2023 Oct 4 doi: 10.1016/j.jcms.2023.09.009. PMID: 37813772
Anand S, Singh A, Bajpai M
J Pediatr Urol 2021 Apr;17(2):183-189. Epub 2020 Dec 19 doi: 10.1016/j.jpurol.2020.12.012. PMID: 33478901
Martínez-Aznar C, Parada-Avendaño I, Gómez-Palacio VE, Abando-Ruiz S, Gil-Albarova J
Jt Dis Relat Surg 2021;32(1):224-229. Epub 2021 Jan 6 doi: 10.5606/ehc.2021.79576. PMID: 33463441Free PMC Article
Smyrnakis I, Andreadakis V, Selimis V, Kalaitzakis M, Bachourou T, Kaloutsakis G, Kymionis GD, Smirnakis S, Aslanides IM
PLoS One 2017;12(8):e0182597. Epub 2017 Aug 11 doi: 10.1371/journal.pone.0182597. PMID: 28800632Free PMC Article

Recent systematic reviews

Neves J, Hsieh C, Nobre IB, Sousa SC, Ouyang C, Maciel A, Duchowski A, Jorge J, Moreira C
Eur J Radiol 2024 Mar;172:111341. Epub 2024 Feb 1 doi: 10.1016/j.ejrad.2024.111341. PMID: 38340426
Yoshitani J, Schoyer B, Shah A, Khanduja V
Int Orthop 2024 Mar;48(3):657-666. Epub 2024 Jan 10 doi: 10.1007/s00264-023-06078-0. PMID: 38195946Free PMC Article
Burstein O, Zevin Z, Geva R
JAMA Netw Open 2021 Mar 1;4(3):e213687. doi: 10.1001/jamanetworkopen.2021.3687. PMID: 33783515Free PMC Article
Anand S, Singh A, Bajpai M
J Pediatr Urol 2021 Apr;17(2):183-189. Epub 2020 Dec 19 doi: 10.1016/j.jpurol.2020.12.012. PMID: 33478901

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Recent activity

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...