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Anti-Ma antibody positivity

MedGen UID:
1814428
•Concept ID:
C5676865
•
Finding
Synonym: Anti-Ma antibody
 
HPO: HP:5000021

Definition

The presence of autoantibodies (immunoglobulins) in the blood circulation that react against Ma. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAnti-Ma antibody positivity

Recent clinical studies

Etiology

Paraneoplastic neurological antibodies: a laboratory experience.
Karim AR, Hughes RG, Winer JB, Williams AC, Bradwell AR
Ann N Y Acad Sci 2005 Jun;1050:274-85. doi: 10.1196/annals.1313.029. PMID: 16014543
Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patients.
Gultekin SH, Rosenfeld MR, Voltz R, Eichen J, Posner JB, Dalmau J
Brain 2000 Jul;123 ( Pt 7):1481-94. doi: 10.1093/brain/123.7.1481. PMID: 10869059

Diagnosis

Anti-Ma-associated paraneoplastic cerebellar degeneration in a patient with nodular lymphocyte-predominant Hodgkin lymphoma: a case report.
Inui R, Saito K, Shimomura Y, Yamashita D, Kawamoto M, Ishikawa T
BMC Neurol 2020 Sep 23;20(1):355. doi: 10.1186/s12883-020-01929-4. PMID: 32967629Free PMC Article
Autoantibodies to mitotic apparatus: association with other autoantibodies and their clinical significance.
Bonaci-Nikolic B, Andrejevic S, Bukilica M, Urosevic I, Nikolic M
J Clin Immunol 2006 Sep;26(5):438-46. Epub 2006 Aug 29 doi: 10.1007/s10875-006-9038-y. PMID: 16941236
Second primary tumor in anti-Ma1/2-positive paraneoplastic limbic encephalitis.
Leyhe T, Schüle R, Schwärzler F, Gasser T, Haarmeier T
J Neurooncol 2006 May;78(1):49-51. Epub 2005 Nov 29 doi: 10.1007/s11060-005-9052-6. PMID: 16314942
Paraneoplastic neurological antibodies: a laboratory experience.
Karim AR, Hughes RG, Winer JB, Williams AC, Bradwell AR
Ann N Y Acad Sci 2005 Jun;1050:274-85. doi: 10.1196/annals.1313.029. PMID: 16014543
Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patients.
Gultekin SH, Rosenfeld MR, Voltz R, Eichen J, Posner JB, Dalmau J
Brain 2000 Jul;123 ( Pt 7):1481-94. doi: 10.1093/brain/123.7.1481. PMID: 10869059

Therapy

Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patients.
Gultekin SH, Rosenfeld MR, Voltz R, Eichen J, Posner JB, Dalmau J
Brain 2000 Jul;123 ( Pt 7):1481-94. doi: 10.1093/brain/123.7.1481. PMID: 10869059

Clinical prediction guides

Immune mediated neurologic dysfunction as a paraneoplastic syndrome in renal cell carcinoma.
Johnson V, Friedman N, Haller NA, Hagel C
J Neurooncol 2008 Dec;90(3):279-81. Epub 2008 Aug 24 doi: 10.1007/s11060-008-9675-5. PMID: 18726185
Autoantibodies to mitotic apparatus: association with other autoantibodies and their clinical significance.
Bonaci-Nikolic B, Andrejevic S, Bukilica M, Urosevic I, Nikolic M
J Clin Immunol 2006 Sep;26(5):438-46. Epub 2006 Aug 29 doi: 10.1007/s10875-006-9038-y. PMID: 16941236
Paraneoplastic limbic encephalitis: neurological symptoms, immunological findings and tumour association in 50 patients.
Gultekin SH, Rosenfeld MR, Voltz R, Eichen J, Posner JB, Dalmau J
Brain 2000 Jul;123 ( Pt 7):1481-94. doi: 10.1093/brain/123.7.1481. PMID: 10869059

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