A rare syndrome with characteristics of hypereosinophilia produced by clonal eosinophils derived from neoplastic stem cells in the absence of any secondary cause of eosinophilia and persisting for at least six months. The condition is associated with signs of organ infiltration, dysfunction and damage. Clinical manifestations are highly variable depending on the organ systems involved, and include dermatologic, pulmonary, cardiac, gastrointestinal and cerebral manifestations among others. [from
SNOMEDCT_US]