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Pericardial tuberculosis

MedGen UID:
18379
•Concept ID:
C0031049
•
Disease or Syndrome
Synonyms: Pericarditides, Tuberculous; Pericarditis, Tuberculous; Tuberculous Pericarditides; Tuberculous Pericarditis
SNOMED CT: Tuberculosis of pericardium (67256000); Tuberculous pericarditis (67256000)
 
Monarch Initiative: MONDO:0005903

Definition

Inflammation of the sac surrounding the heart (pericardium) due to mycobacterium tuberculosis infection. Pericarditis can lead to swelling (pericardial effusion), compression of the heart (cardiac tamponade), and preventing normal beating of the heart. [from MONDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPericardial tuberculosis

Professional guidelines

PubMed

The management of tuberculous pericardial effusion: experience in 233 consecutive patients.
Reuter H, Burgess LJ, Louw VJ, Doubell AF
Cardiovasc J S Afr 2007 Jan-Feb;18(1):20-5. PMID: 17392991

Recent clinical studies

Etiology

Adjunctive corticosteroid therapy in patients with pulmonary tuberculosis.
Lemos CX, Anton C, Machado FD, Bernardi RM, Freitas AA, Silva DR
Rev Assoc Med Bras (1992) 2022 Sep;68(9):1199-1203. doi: 10.1590/1806-9282.20220196. PMID: 36228251Free PMC Article
Epidemiological characteristics and some risk factors of extrapulmonary tuberculosis in Larache, Morocco.
Sbayi A, Arfaoui A, Janah H, Koraichi SE, Quyou A
Pan Afr Med J 2020;36:381. Epub 2020 Aug 31 doi: 10.11604/pamj.2020.36.381.24870. PMID: 33235658Free PMC Article
Diffuse pseudo-tumoral pericardial tuberculosis.
Colin GC, Pouleur AC, Belkhir L, Baldin P, Gerber B
Eur Heart J Cardiovasc Imaging 2017 Apr 1;18(4):484. doi: 10.1093/ehjci/jew306. PMID: 28065910
The use of adenosine deaminase and interferon-gamma as diagnostic tools for tuberculous pericarditis.
Burgess LJ, Reuter H, Carstens ME, Taljaard JJ, Doubell AF
Chest 2002 Sep;122(3):900-5. doi: 10.1378/chest.122.3.900. PMID: 12226030
Tuberculous pericarditis in children: a review of 44 cases.
Hugo-Hamman CT, Scher H, De Moor MM
Pediatr Infect Dis J 1994 Jan;13(1):13-8. doi: 10.1097/00006454-199401000-00004. PMID: 8170726

Diagnosis

Comparison of the frequency and phenotypic profile of Mycobacterium tuberculosis-specific CD4 T cells between the site of disease and blood in pericardial tuberculosis.
Du Bruyn E, Ruzive S, Howlett P, Jacobs AJ, Arlehamn CSL, Sette A, Sher A, Mayer-Barber KD, Barber DL, Mayosi B, Ntsekhe M, Wilkinson RJ, Riou C
Front Immunol 2022;13:1009016. Epub 2022 Nov 11 doi: 10.3389/fimmu.2022.1009016. PMID: 36439130Free PMC Article
Diffuse pseudo-tumoral pericardial tuberculosis.
Colin GC, Pouleur AC, Belkhir L, Baldin P, Gerber B
Eur Heart J Cardiovasc Imaging 2017 Apr 1;18(4):484. doi: 10.1093/ehjci/jew306. PMID: 28065910
Poor Penetration of Antibiotics Into Pericardium in Pericardial Tuberculosis.
Shenje J, Ifeoma Adimora-Nweke F, Ross IL, Ntsekhe M, Wiesner L, Deffur A, McIlleron HM, Pasipanodya J, Gumbo T, Mayosi BM
EBioMedicine 2015 Nov;2(11):1640-9. Epub 2015 Sep 16 doi: 10.1016/j.ebiom.2015.09.025. PMID: 26870790Free PMC Article
Pericardial tuberculosis.
Cataño JC
Am J Trop Med Hyg 2013 Jul;89(1):1-2. doi: 10.4269/ajtmh.12-0781. PMID: 23843490Free PMC Article
Cardiac manifestations of HIV infection: an African perspective.
Ntsekhe M, Mayosi BM
Nat Clin Pract Cardiovasc Med 2009 Feb;6(2):120-7. Epub 2008 Dec 23 doi: 10.1038/ncpcardio1437. PMID: 19104517

Therapy

Adjunctive corticosteroid therapy in patients with pulmonary tuberculosis.
Lemos CX, Anton C, Machado FD, Bernardi RM, Freitas AA, Silva DR
Rev Assoc Med Bras (1992) 2022 Sep;68(9):1199-1203. doi: 10.1590/1806-9282.20220196. PMID: 36228251Free PMC Article
Corticosteroids as an adjunct to tuberculosis therapy.
Schutz C, Davis AG, Sossen B, Lai RP, Ntsekhe M, Harley YX, Wilkinson RJ
Expert Rev Respir Med 2018 Oct;12(10):881-891. Epub 2018 Sep 6 doi: 10.1080/17476348.2018.1515628. PMID: 30138039Free PMC Article
Diffuse pseudo-tumoral pericardial tuberculosis.
Colin GC, Pouleur AC, Belkhir L, Baldin P, Gerber B
Eur Heart J Cardiovasc Imaging 2017 Apr 1;18(4):484. doi: 10.1093/ehjci/jew306. PMID: 28065910
Poor Penetration of Antibiotics Into Pericardium in Pericardial Tuberculosis.
Shenje J, Ifeoma Adimora-Nweke F, Ross IL, Ntsekhe M, Wiesner L, Deffur A, McIlleron HM, Pasipanodya J, Gumbo T, Mayosi BM
EBioMedicine 2015 Nov;2(11):1640-9. Epub 2015 Sep 16 doi: 10.1016/j.ebiom.2015.09.025. PMID: 26870790Free PMC Article
Corticosteroids and tuberculosis.
Senderovitz T, Viskum K
Respir Med 1994 Sep;88(8):561-5. doi: 10.1016/s0954-6111(05)80002-2. PMID: 7991879

Prognosis

Shorter antitubercular therapy for extrapulmonary tuberculosis - a case report.
Ravikumar DB, Sivasubramanian BP, Singla A, Venu R, Shekar SP
BMC Infect Dis 2024 Jan 15;24(1):86. doi: 10.1186/s12879-023-08941-2. PMID: 38225554Free PMC Article
Nocardia beijingensis pericarditis presenting with cardiac tamponade: A case report.
Laksananun N, Salee P, Kaewpoowat Q
Int J STD AIDS 2018 Apr;29(5):515-519. Epub 2017 Oct 23 doi: 10.1177/0956462417736986. PMID: 29059035
Diffuse pseudo-tumoral pericardial tuberculosis.
Colin GC, Pouleur AC, Belkhir L, Baldin P, Gerber B
Eur Heart J Cardiovasc Imaging 2017 Apr 1;18(4):484. doi: 10.1093/ehjci/jew306. PMID: 28065910
The use of adenosine deaminase and interferon-gamma as diagnostic tools for tuberculous pericarditis.
Burgess LJ, Reuter H, Carstens ME, Taljaard JJ, Doubell AF
Chest 2002 Sep;122(3):900-5. doi: 10.1378/chest.122.3.900. PMID: 12226030
Tuberculous pericarditis in children: a review of 44 cases.
Hugo-Hamman CT, Scher H, De Moor MM
Pediatr Infect Dis J 1994 Jan;13(1):13-8. doi: 10.1097/00006454-199401000-00004. PMID: 8170726

Clinical prediction guides

Comparison of the frequency and phenotypic profile of Mycobacterium tuberculosis-specific CD4 T cells between the site of disease and blood in pericardial tuberculosis.
Du Bruyn E, Ruzive S, Howlett P, Jacobs AJ, Arlehamn CSL, Sette A, Sher A, Mayer-Barber KD, Barber DL, Mayosi B, Ntsekhe M, Wilkinson RJ, Riou C
Front Immunol 2022;13:1009016. Epub 2022 Nov 11 doi: 10.3389/fimmu.2022.1009016. PMID: 36439130Free PMC Article
A primary intestinal lymphangiectasia hiding the diagnosis of pleural and pericardial tuberculosis: a clinical observation.
Hammi S, Berrani H, Benouchen T, Lamlami N, Elkhiyat I, Bourkadi JE
Pan Afr Med J 2017;26:89. Epub 2017 Feb 23 doi: 10.11604/pamj.2017.26.89.11125. PMID: 28491220Free PMC Article
Poor Penetration of Antibiotics Into Pericardium in Pericardial Tuberculosis.
Shenje J, Ifeoma Adimora-Nweke F, Ross IL, Ntsekhe M, Wiesner L, Deffur A, McIlleron HM, Pasipanodya J, Gumbo T, Mayosi BM
EBioMedicine 2015 Nov;2(11):1640-9. Epub 2015 Sep 16 doi: 10.1016/j.ebiom.2015.09.025. PMID: 26870790Free PMC Article
Cardiac manifestations of HIV infection: an African perspective.
Ntsekhe M, Mayosi BM
Nat Clin Pract Cardiovasc Med 2009 Feb;6(2):120-7. Epub 2008 Dec 23 doi: 10.1038/ncpcardio1437. PMID: 19104517
The use of adenosine deaminase and interferon-gamma as diagnostic tools for tuberculous pericarditis.
Burgess LJ, Reuter H, Carstens ME, Taljaard JJ, Doubell AF
Chest 2002 Sep;122(3):900-5. doi: 10.1378/chest.122.3.900. PMID: 12226030

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