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Ambiguous facial expression

MedGen UID:
1841690
•Concept ID:
C5826921
•
Finding
HPO: HP:5200013

Definition

Spontaneous production of communicative facial expressions that have poor quality or are perceived as odd or mechanical. This may include inaccurate mimicry of typical facial expressions. These expressions may be difficult to interpret for someone who is not familiar with the individual making the expression. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAmbiguous facial expression

Professional guidelines

PubMed

Altered passive eruption (APE) 
and active secondary eruption (ASE): differential diagnosis and management.
Ahmad I
Int J Esthet Dent 2017;12(3):352-376. PMID: 28717793
Sunnybrook facial grading system: reliability and criteria for grading.
Neely JG, Cherian NG, Dickerson CB, Nedzelski JM
Laryngoscope 2010 May;120(5):1038-45. doi: 10.1002/lary.20868. PMID: 20422701

Recent clinical studies

Etiology

Abnormal ambiguous facial expression recognition in Chinese patients with schizophrenia.
Lyu X, Chi Y, Wang Z, Shao X, Zhang G, Li C, Dong C, Wang X, Li X, Zhu C, Xu X, Du X
BMC Psychiatry 2024 Mar 26;24(1):226. doi: 10.1186/s12888-024-05685-4. PMID: 38532335Free PMC Article
Interpretive bias of ambiguous facial expressions in older adults with depressive symptoms.
Dai B, Li J, Chen T, Li Q
Psych J 2015 Mar;4(1):28-37. doi: 10.1002/pchj.85. PMID: 26263528
A negativity bias for ambiguous facial-expression valence during childhood: converging evidence from behavior and facial corrugator muscle responses.
Tottenham N, Phuong J, Flannery J, Gabard-Durnam L, Goff B
Emotion 2013 Feb;13(1):92-103. Epub 2012 Aug 20 doi: 10.1037/a0029431. PMID: 22906084Free PMC Article
An intact social cognitive process in schizophrenia: situational context effects on perception of facial affect.
Lee J, Kern RS, Harvey PO, Horan WP, Kee KS, Ochsner K, Penn DL, Green MF
Schizophr Bull 2013 May;39(3):640-7. Epub 2012 Apr 24 doi: 10.1093/schbul/sbs063. PMID: 22532704Free PMC Article

Prognosis

Neural signatures of individual variability in context-dependent perception of ambiguous facial expression.
Kim KI, Jung WH, Woo CW, Kim H
Neuroimage 2022 Sep;258:119355. Epub 2022 Jun 1 doi: 10.1016/j.neuroimage.2022.119355. PMID: 35660000

Clinical prediction guides

Abnormal ambiguous facial expression recognition in Chinese patients with schizophrenia.
Lyu X, Chi Y, Wang Z, Shao X, Zhang G, Li C, Dong C, Wang X, Li X, Zhu C, Xu X, Du X
BMC Psychiatry 2024 Mar 26;24(1):226. doi: 10.1186/s12888-024-05685-4. PMID: 38532335Free PMC Article
Neural signatures of individual variability in context-dependent perception of ambiguous facial expression.
Kim KI, Jung WH, Woo CW, Kim H
Neuroimage 2022 Sep;258:119355. Epub 2022 Jun 1 doi: 10.1016/j.neuroimage.2022.119355. PMID: 35660000
Neural basis of negativity bias in the perception of ambiguous facial expression.
Ito T, Yokokawa K, Yahata N, Isato A, Suhara T, Yamada M
Sci Rep 2017 Mar 24;7(1):420. doi: 10.1038/s41598-017-00502-3. PMID: 28341827Free PMC Article
Interpretive bias of ambiguous facial expressions in older adults with depressive symptoms.
Dai B, Li J, Chen T, Li Q
Psych J 2015 Mar;4(1):28-37. doi: 10.1002/pchj.85. PMID: 26263528

Supplemental Content

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    Clinical resources

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    Reviews

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