Elevated circulating pancreatic secretory trypsin inhibitor activity

MedGen UID:: 1841940
•Concept ID:: C5826467
•: Finding

Synonyms:	Elevated circulating serine protease inhibitor Kazal type I; Elevated circulating SPINK1 activity

HPO:	HP:0034545

Definition

Increased activity of the enzyme pancreatic secretory trypsin inhibitor in the blood circulation. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVElevated circulating pancreatic secretory trypsin inhibitor activity

Phenotypic abnormality
- Abnormality of metabolism/homeostasis
  - Abnormal enzyme concentration or activity
    - Abnormal circulating enzyme concentration or activity
      - Elevated circulating pancreatic secretory trypsin inhibitor activity

Recent clinical studies

Diagnosis

Plasma alpha 2-macroglobulin-trypsin complexlike substance (MTLS) in pancreatic disease.

Kato M, Hayakawa S, Naruse S, Kitagawa M, Nakae Y, Hayakawa T
J Clin Lab Anal 1996;10(6):399-402. doi: 10.1002/(SICI)1098-2825(1996)10:6<399::AID-JCLA14>3.0.CO;2-S. PMID: 8951609

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Elevated circulating pancreatic secretory trypsin inhibitor activity

Definition

Term Hierarchy

Recent clinical studies

Diagnosis

Supplemental Content

Table of contents

Clinical resources

Consumer resources

Reviews

Recent activity