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Benign neoplasm of neck

MedGen UID:
195775
•Concept ID:
C0684815
•
Neoplastic Process
Synonyms: Benign Neck Neoplasm; benign neck neoplasm; Benign Neck Tumor; benign neck tumor; benign neck tumour; Benign Neoplasm of Neck; benign neoplasm of neck; Benign Neoplasm of the Neck; benign neoplasm of the neck; Benign tumor of neck; Benign Tumor of Neck; benign tumor of neck; Benign Tumor of the Neck; benign tumor of the neck; benign tumour of neck; benign tumour of the neck; neck benign neoplasm
SNOMED CT: Benign tumor of neck (92246000); Benign neoplasm of neck (92246000)
 
Monarch Initiative: MONDO:0021455

Definition

A neoplasm that arises from the neck region and is characterized by the absence of atypical or malignant cytological and architectural features, and absence of invasive features or metastatic potential. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBenign neoplasm of neck

Professional guidelines

PubMed

2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management.
Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Thyroid cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up†.
Filetti S, Durante C, Hartl D, Leboulleux S, Locati LD, Newbold K, Papotti MG, Berruti A; ESMO Guidelines Committee. Electronic address: clinicalguidelines@esmo.org
Ann Oncol 2019 Dec 1;30(12):1856-1883. doi: 10.1093/annonc/mdz400. PMID: 31549998
Delineation of the neck node levels for head and neck tumors: a 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines.
Grégoire V, Ang K, Budach W, Grau C, Hamoir M, Langendijk JA, Lee A, Le QT, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Lengele B
Radiother Oncol 2014 Jan;110(1):172-81. Epub 2013 Oct 31 doi: 10.1016/j.radonc.2013.10.010. PMID: 24183870

Recent clinical studies

Etiology

2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management.
Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Congenital Neck Masses.
Pupić-Bakrač J, Pupić-Bakrač A, Novaković J, Skitarelić N
J Craniofac Surg 2021 Jun 1;32(4):1417-1420. doi: 10.1097/SCS.0000000000007122. PMID: 33170821
Congenital Neck Masses.
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417
CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855
Delineation of the neck node levels for head and neck tumors: a 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines.
Grégoire V, Ang K, Budach W, Grau C, Hamoir M, Langendijk JA, Lee A, Le QT, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Lengele B
Radiother Oncol 2014 Jan;110(1):172-81. Epub 2013 Oct 31 doi: 10.1016/j.radonc.2013.10.010. PMID: 24183870

Diagnosis

2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management.
Durante C, Hegedüs L, Czarniecka A, Paschke R, Russ G, Schmitt F, Soares P, Solymosi T, Papini E
Eur Thyroid J 2023 Oct 1;12(5) Epub 2023 Aug 14 doi: 10.1530/ETJ-23-0067. PMID: 37358008Free PMC Article
Repetitive trauma-induced extra-nuchal-type fibroma.
Jayaram PR, Walsh J, Lari H, Mohammad N, Mallinson PI, Ouellette HA
Skeletal Radiol 2022 Mar;51(3):681-685. Epub 2021 Sep 23 doi: 10.1007/s00256-021-03912-7. PMID: 34554278Free PMC Article
Evaluation and Management of a Neck Mass.
Chorath K, Rajasekaran K
Med Clin North Am 2021 Sep;105(5):827-837. Epub 2021 Jul 12 doi: 10.1016/j.mcna.2021.05.005. PMID: 34391536
Congenital Neck Masses.
Pupić-Bakrač J, Pupić-Bakrač A, Novaković J, Skitarelić N
J Craniofac Surg 2021 Jun 1;32(4):1417-1420. doi: 10.1097/SCS.0000000000007122. PMID: 33170821
Congenital Neck Masses.
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417

Therapy

Thyroidectomy without Radioiodine in Patients with Low-Risk Thyroid Cancer.
Leboulleux S, Bournaud C, Chougnet CN, Zerdoud S, Al Ghuzlan A, Catargi B, Do Cao C, Kelly A, Barge ML, Lacroix L, Dygai I, Vera P, Rusu D, Schneegans O, Benisvy D, Klein M, Roux J, Eberle MC, Bastie D, Nascimento C, Giraudet AL, Le Moullec N, Bardet S, Drui D, Roudaut N, Godbert Y, Morel O, Drutel A, Lamartina L, Schvartz C, Velayoudom FL, Schlumberger MJ, Leenhardt L, Borget I
N Engl J Med 2022 Mar 10;386(10):923-932. doi: 10.1056/NEJMoa2111953. PMID: 35263518
Use of a novel sealant film in head and neck surgery.
Tirelli G, Gatto A, Brancatelli S, Piccinato A, Longoni V, Tofanelli M
Am J Otolaryngol 2022 Jan-Feb;43(1):103249. Epub 2021 Sep 22 doi: 10.1016/j.amjoto.2021.103249. PMID: 34600411
Platelet-rich fibrin as a treatment option for osteoradionecrosis: A literature review.
Harris P, Durand R, Schmittbuhl M, Kabir R
J Stomatol Oral Maxillofac Surg 2022 Jun;123(3):e20-e27. Epub 2021 Jun 23 doi: 10.1016/j.jormas.2021.06.005. PMID: 34171527
Influence of preoperative radiotherapy on head and neck free-flap reconstruction: Systematic review and meta-analysis.
Mijiti A, Kuerbantayi N, Zhang ZQ, Su MY, Zhang XH, Huojia M
Head Neck 2020 Aug;42(8):2165-2180. Epub 2020 Mar 4 doi: 10.1002/hed.26136. PMID: 32129547
CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855

Prognosis

Osteolipoma of head and neck - a review.
Wong BLK, Hogan C
Braz J Otorhinolaryngol 2022 Nov-Dec;88 Suppl 4(Suppl 4):S177-S187. Epub 2022 May 20 doi: 10.1016/j.bjorl.2022.04.002. PMID: 35659712Free PMC Article
Thyroidectomy without Radioiodine in Patients with Low-Risk Thyroid Cancer.
Leboulleux S, Bournaud C, Chougnet CN, Zerdoud S, Al Ghuzlan A, Catargi B, Do Cao C, Kelly A, Barge ML, Lacroix L, Dygai I, Vera P, Rusu D, Schneegans O, Benisvy D, Klein M, Roux J, Eberle MC, Bastie D, Nascimento C, Giraudet AL, Le Moullec N, Bardet S, Drui D, Roudaut N, Godbert Y, Morel O, Drutel A, Lamartina L, Schvartz C, Velayoudom FL, Schlumberger MJ, Leenhardt L, Borget I
N Engl J Med 2022 Mar 10;386(10):923-932. doi: 10.1056/NEJMoa2111953. PMID: 35263518
Incidence and survival of head and neck cancer in the Faroe Islands.
Olsen SH, Friborg J, Ellefsen B, Jakobsen KK, Aanæs K
Int J Circumpolar Health 2021 Dec;80(1):1894697. doi: 10.1080/22423982.2021.1894697. PMID: 33719929Free PMC Article
Survival outcomes after treatment of cancer of the oral cavity (1985-2015).
Zanoni DK, Montero PH, Migliacci JC, Shah JP, Wong RJ, Ganly I, Patel SG
Oral Oncol 2019 Mar;90:115-121. Epub 2019 Feb 15 doi: 10.1016/j.oraloncology.2019.02.001. PMID: 30846169Free PMC Article
Congenital Neck Masses.
Quintanilla-Dieck L, Penn EB Jr
Clin Perinatol 2018 Dec;45(4):769-785. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.012. PMID: 30396417

Clinical prediction guides

Advances in and applications of imaging and radiomics in head and neck cancer survivorship.
Wishart LR, Ward EC, Galloway G
Curr Opin Otolaryngol Head Neck Surg 2023 Dec 1;31(6):368-373. Epub 2023 Aug 4 doi: 10.1097/MOO.0000000000000918. PMID: 37548514
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Hypopharynx, Larynx, Trachea and Parapharyngeal Space.
Zidar N, Gale N
Head Neck Pathol 2022 Mar;16(1):31-39. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01405-6. PMID: 35312977Free PMC Article
Contemporary Management of Parapharyngeal Tumors.
Strohl MP, El-Sayed IH
Curr Oncol Rep 2019 Nov 14;21(11):103. doi: 10.1007/s11912-019-0853-8. PMID: 31728649
CT-based delineation of organs at risk in the head and neck region: DAHANCA, EORTC, GORTEC, HKNPCSG, NCIC CTG, NCRI, NRG Oncology and TROG consensus guidelines.
Brouwer CL, Steenbakkers RJ, Bourhis J, Budach W, Grau C, Grégoire V, van Herk M, Lee A, Maingon P, Nutting C, O'Sullivan B, Porceddu SV, Rosenthal DI, Sijtsema NM, Langendijk JA
Radiother Oncol 2015 Oct;117(1):83-90. Epub 2015 Aug 13 doi: 10.1016/j.radonc.2015.07.041. PMID: 26277855
Infrahyoid neck.
Sigal R
Radiol Clin North Am 1998 Sep;36(5):781-99, v. doi: 10.1016/s0033-8389(05)70064-6. PMID: 9747189

Recent systematic reviews

Systematic review of head and neck lymphedema assessment.
Fadhil M, Singh R, Havas T, Jacobson I
Head Neck 2022 Oct;44(10):2301-2315. Epub 2022 Jul 11 doi: 10.1002/hed.27136. PMID: 35818729
Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Odontogenic and Maxillofacial Bone Tumours.
Vered M, Wright JM
Head Neck Pathol 2022 Mar;16(1):63-75. Epub 2022 Mar 21 doi: 10.1007/s12105-021-01404-7. PMID: 35312978Free PMC Article
Radiation-Induced Sarcomas of the Head and Neck: A Systematic Review.
Coca-Pelaz A, Mäkitie AA, Strojan P, Corry J, Eisbruch A, Beitler JJ, Nuyts S, Smee R, Langendijk JA, Mendenhall WM, Piazza C, Rinaldo A, Ferlito A
Adv Ther 2021 Jan;38(1):90-108. Epub 2020 Nov 13 doi: 10.1007/s12325-020-01556-y. PMID: 33184778Free PMC Article
Exercise and Nutrition Interventions in Patients with Head and Neck Cancer during Curative Treatment: A Systematic Review and Meta-Analysis.
Bye A, Sandmael JA, Stene GB, Thorsen L, Balstad TR, Solheim TS, Pripp AH, Oldervoll LM
Nutrients 2020 Oct 22;12(11) doi: 10.3390/nu12113233. PMID: 33105699Free PMC Article
Radiation-Associated Sarcoma of the Neck: Case Series and Systematic Review.
Williams L, Tmanova L, Mydlarz WK, Page B, Richmon JD, Quon H, Schmitt NC
Ann Otol Rhinol Laryngol 2018 Oct;127(10):735-740. Epub 2018 Jul 26 doi: 10.1177/0003489418789966. PMID: 30047787

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