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Metastatic Malignant Neoplasm in the Ciliary Body

MedGen UID:
195787
Concept ID:
C0686463
Neoplastic Process
Synonyms: Metastasis to the Ciliary Body; Metastatic malignant neoplasm of ciliary body; Metastatic malignant neoplasm to ciliary body; Metastatic Malignant Neoplasm to the Ciliary Body; Metastatic Neoplasm to the Ciliary Body; Metastatic Tumor to the Ciliary Body; Secondary malignant neoplasm of ciliary body
SNOMED CT: Secondary malignant neoplasm of ciliary body (94255003); Metastatic malignant neoplasm to ciliary body (94255003); Metastatic malignant neoplasm of ciliary body (94255003)

Definition

A malignant neoplasm that has spread to the ciliary body from another anatomic site. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMetastatic Malignant Neoplasm in the Ciliary Body

Professional guidelines

PubMed

Dogrusöz M, Jager MJ, Damato B
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):186-196. doi: 10.22608/APO.201734. PMID: 28399342
Carvajal RD, Schwartz GK, Tezel T, Marr B, Francis JH, Nathan PD
Br J Ophthalmol 2017 Jan;101(1):38-44. Epub 2016 Aug 29 doi: 10.1136/bjophthalmol-2016-309034. PMID: 27574175Free PMC Article
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article

Recent clinical studies

Etiology

Zabor EC, Radivoyevitch T, Singh AD, Kilic E, de Klein JEMM, Kalirai H, Coupland SE
Ophthalmol Retina 2021 Jun;5(6):536-542. Epub 2020 Sep 23 doi: 10.1016/j.oret.2020.09.015. PMID: 32979556
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article
Furdova A, Chynoransky M, Krajcova P
Bratisl Lek Listy 2011;112(8):466-8. PMID: 21863619
Laver NV, McLaughlin ME, Duker JS
Arch Pathol Lab Med 2010 Dec;134(12):1778-84. doi: 10.5858/2009-0441-RAR.1. PMID: 21128775
Coupland SE, Damato B
Clin Exp Ophthalmol 2008 Aug;36(6):564-78. doi: 10.1111/j.1442-9071.2008.01843.x. PMID: 18954321

Diagnosis

Dogrusöz M, Jager MJ, Damato B
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):186-196. doi: 10.22608/APO.201734. PMID: 28399342
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article
Kaliki S, Shields CL, Shields JA
Indian J Ophthalmol 2015 Feb;63(2):93-102. doi: 10.4103/0301-4738.154367. PMID: 25827538Free PMC Article
Furdova A, Chynoransky M, Krajcova P
Bratisl Lek Listy 2011;112(8):466-8. PMID: 21863619
Laver NV, McLaughlin ME, Duker JS
Arch Pathol Lab Med 2010 Dec;134(12):1778-84. doi: 10.5858/2009-0441-RAR.1. PMID: 21128775

Therapy

Rantala ES, Parrozzani R, Hernberg MM, Chiarion-Sileni V, Kivelä TT, Midena E
Am J Ophthalmol 2023 Feb;246:258-272. Epub 2022 Nov 1 doi: 10.1016/j.ajo.2022.10.017. PMID: 36328199
Romano MR, Catania F, Confalonieri F, Zollet P, Allegrini D, Sergenti J, Lanza FB, Ferrara M, Angi M
Int J Mol Sci 2021 Sep 17;22(18) doi: 10.3390/ijms221810066. PMID: 34576231Free PMC Article
Camp DA, Yadav P, Dalvin LA, Shields CL
Curr Opin Ophthalmol 2019 Mar;30(2):71-81. doi: 10.1097/ICU.0000000000000550. PMID: 30562240
Damato B
Clin Exp Ophthalmol 2004 Dec;32(6):639-47. doi: 10.1111/j.1442-9071.2004.00917.x. PMID: 15575836
Shields JA, Shields CL
Mayo Clin Proc 1993 Dec;68(12):1196-200. doi: 10.1016/s0025-6196(12)60072-x. PMID: 8246622

Prognosis

Zhang S, Wang K, Zhu X, Cherepanoff S, Conway RM, Madigan MC, Zhu L, Murray M, Zhou F
Biochimie 2022 Jun;197:9-18. Epub 2022 Jan 29 doi: 10.1016/j.biochi.2022.01.017. PMID: 35093452
Dogrusöz M, Jager MJ, Damato B
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):186-196. doi: 10.22608/APO.201734. PMID: 28399342
Carvajal RD, Schwartz GK, Tezel T, Marr B, Francis JH, Nathan PD
Br J Ophthalmol 2017 Jan;101(1):38-44. Epub 2016 Aug 29 doi: 10.1136/bjophthalmol-2016-309034. PMID: 27574175Free PMC Article
Chattopadhyay C, Kim DW, Gombos DS, Oba J, Qin Y, Williams MD, Esmaeli B, Grimm EA, Wargo JA, Woodman SE, Patel SP
Cancer 2016 Aug 1;122(15):2299-312. Epub 2016 Mar 15 doi: 10.1002/cncr.29727. PMID: 26991400Free PMC Article
Laver NV, McLaughlin ME, Duker JS
Arch Pathol Lab Med 2010 Dec;134(12):1778-84. doi: 10.5858/2009-0441-RAR.1. PMID: 21128775

Clinical prediction guides

Rantala ES, Parrozzani R, Hernberg MM, Chiarion-Sileni V, Kivelä TT, Midena E
Am J Ophthalmol 2023 Feb;246:258-272. Epub 2022 Nov 1 doi: 10.1016/j.ajo.2022.10.017. PMID: 36328199
Zabor EC, Radivoyevitch T, Singh AD, Kilic E, de Klein JEMM, Kalirai H, Coupland SE
Ophthalmol Retina 2021 Jun;5(6):536-542. Epub 2020 Sep 23 doi: 10.1016/j.oret.2020.09.015. PMID: 32979556
Dogrusöz M, Jager MJ, Damato B
Asia Pac J Ophthalmol (Phila) 2017 Mar-Apr;6(2):186-196. doi: 10.22608/APO.201734. PMID: 28399342
Kaliki S, Shields CL, Shields JA
Indian J Ophthalmol 2015 Feb;63(2):93-102. doi: 10.4103/0301-4738.154367. PMID: 25827538Free PMC Article
Shields JA, Shields CL, Donoso LA
Surv Ophthalmol 1991 Nov-Dec;36(3):161-95. doi: 10.1016/0039-6257(91)90001-v. PMID: 1776122

Recent systematic reviews

Romano MR, Catania F, Confalonieri F, Zollet P, Allegrini D, Sergenti J, Lanza FB, Ferrara M, Angi M
Int J Mol Sci 2021 Sep 17;22(18) doi: 10.3390/ijms221810066. PMID: 34576231Free PMC Article
Schmalfuss TR, Picetti E, Pakter HM
Arq Bras Oftalmol 2018 Jun;81(3):254-261. doi: 10.5935/0004-2749.20180051. PMID: 29924202
Zhao M, Mu Y, Dang Y, Zhu Y
Int J Clin Exp Pathol 2014;7(11):8163-9. Epub 2014 Oct 15 PMID: 25550867Free PMC Article

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