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Hepatic Infection

MedGen UID:
206810
•Concept ID:
C1112211
•
Disease or Syndrome

Definition

An acute or chronic infectious process affecting the liver. [from NCI]

Professional guidelines

PubMed

Taiwan consensus statement on the management of chronic hepatitis B.
Chien RN, Kao JH, Peng CY, Chen CH, Liu CJ, Huang YH, Hu TH, Yang HI, Lu SN, Ni YH, Chuang WL, Lee CM, Wu JC, Chen PJ, Liaw YF
J Formos Med Assoc 2019 Jan;118(1 Pt 1):7-38. Epub 2018 Dec 6 doi: 10.1016/j.jfma.2018.11.008. PMID: 30527436
Triple hepatitis: frequency and treatment outcome of co/super-infection of hepatitis C and D among patients of hepatitis B.
Zuberi BF, Afsar S, Quraishy MS
J Coll Physicians Surg Pak 2008 Jul;18(7):404-7. PMID: 18760062
Clinical utility of liver biopsy in patients with serum antibodies to the human immunodeficiency virus.
Cappell MS, Schwartz MS, Biempica L
Am J Med 1990 Feb;88(2):123-30. doi: 10.1016/0002-9343(90)90460-u. PMID: 2405658

Recent clinical studies

Etiology

Extra-hepatic infection of hepatitis C virus in the colon tissue and its relationship with hepatitis C virus pathogenesis.
Hetta HF, Mekky MA, Khalil NK, Mohamed WA, El-Feky MA, Ahmed SH, Daef EA, Medhat A, Nassar MI, Sherman KE, Shata MTM
J Med Microbiol 2016 Aug;65(8):703-712. Epub 2016 May 10 doi: 10.1099/jmm.0.000272. PMID: 27166142Free PMC Article
Risk factors of hepatitis C infection among Egyptian blood donors.
Awadalla HI, Ragab MH, Nassar NA, Osman MA
Cent Eur J Public Health 2011 Dec;19(4):217-21. doi: 10.21101/cejph.a3628. PMID: 22432397
Gender disparity in infections of Hepatitis B virus.
Baig S
J Coll Physicians Surg Pak 2009 Sep;19(9):598-600. PMID: 19728952
Triple hepatitis: frequency and treatment outcome of co/super-infection of hepatitis C and D among patients of hepatitis B.
Zuberi BF, Afsar S, Quraishy MS
J Coll Physicians Surg Pak 2008 Jul;18(7):404-7. PMID: 18760062
Hepatitis due to herpes simplex virus in marrow-transplant recipients.
Johnson JR, Egaas S, Gleaves CA, Hackman R, Bowden RA
Clin Infect Dis 1992 Jan;14(1):38-45. doi: 10.1093/clinids/14.1.38. PMID: 1571460

Diagnosis

Typical imaging finding of hepatic infections: a pictorial essay.
Malekzadeh S, Widmer L, Salahshour F, Egger B, Ronot M, Thoeny HC
Abdom Radiol (NY) 2021 Feb;46(2):544-561. Epub 2020 Jul 26 doi: 10.1007/s00261-020-02642-z. PMID: 32715334Free PMC Article
Imaging of hepatic infections.
Doyle DJ, Hanbidge AE, O'Malley ME
Clin Radiol 2006 Sep;61(9):737-48. doi: 10.1016/j.crad.2006.03.010. PMID: 16905380
Pathophysiology of visceral leishmaniasis - some recent concepts.
Malla N, Mahajan RC
Indian J Med Res 2006 Mar;123(3):267-74. PMID: 16778309
Hepatobiliary manifestations of the acquired immune deficiency syndrome.
Cappell MS
Am J Gastroenterol 1991 Jan;86(1):1-15. PMID: 1986533
Clinical utility of liver biopsy in patients with serum antibodies to the human immunodeficiency virus.
Cappell MS, Schwartz MS, Biempica L
Am J Med 1990 Feb;88(2):123-30. doi: 10.1016/0002-9343(90)90460-u. PMID: 2405658

Therapy

Pre-erythrocytic Activity of M5717 in Monotherapy and Combination in Preclinical Plasmodium Infection Models.
Fontinha D, Arez F, Gal IR, Nogueira G, Moita D, Baeurle THH, Brito C, Spangenberg T, Alves PM, Prudêncio M
ACS Infect Dis 2022 Apr 8;8(4):721-727. Epub 2022 Mar 21 doi: 10.1021/acsinfecdis.1c00640. PMID: 35312290Free PMC Article
Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting Plasmodium Hepatic Infection.
Arez F, Rebelo SP, Fontinha D, Simão D, Martins TR, Machado M, Fischli C, Oeuvray C, Badolo L, Carrondo MJT, Rottmann M, Spangenberg T, Brito C, Greco B, Prudêncio M, Alves PM
ACS Infect Dis 2019 Nov 8;5(11):1831-1842. Epub 2019 Sep 13 doi: 10.1021/acsinfecdis.9b00144. PMID: 31479238
Prime and target immunization protects against liver-stage malaria in mice.
Gola A, Silman D, Walters AA, Sridhar S, Uderhardt S, Salman AM, Halbroth BR, Bellamy D, Bowyer G, Powlson J, Baker M, Venkatraman N, Poulton I, Berrie E, Roberts R, Lawrie AM, Angus B, Khan SM, Janse CJ, Ewer KJ, Germain RN, Spencer AJ, Hill AVS
Sci Transl Med 2018 Sep 26;10(460) doi: 10.1126/scitranslmed.aap9128. PMID: 30257955
Peginterferon-alfa mono-therapy in the treatment of acute hepatitis C in HIV-infection.
Boesecke C, van Assen S, Stellbrink HJ, Baumgarten A, Ingiliz P, Strassburg CP, Schwarze-Zander C, Wasmuth JC, Hoepelman AI, Rockstroh JK, Arends JE
J Viral Hepat 2014 Nov;21(11):780-5. Epub 2014 Jul 9 doi: 10.1111/jvh.12272. PMID: 25040149
Fatal, complete splenic infarction and hepatic infection due to disseminated Trichosporon beigelii infection: CT findings.
Viscomi SG, Mortelé KJ, Cantisani V, Glickman J, Silverman SG
Abdom Imaging 2004 Mar-Apr;29(2):228-30. doi: 10.1007/s00261-003-0099-6. PMID: 15290951

Prognosis

Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting Plasmodium Hepatic Infection.
Arez F, Rebelo SP, Fontinha D, Simão D, Martins TR, Machado M, Fischli C, Oeuvray C, Badolo L, Carrondo MJT, Rottmann M, Spangenberg T, Brito C, Greco B, Prudêncio M, Alves PM
ACS Infect Dis 2019 Nov 8;5(11):1831-1842. Epub 2019 Sep 13 doi: 10.1021/acsinfecdis.9b00144. PMID: 31479238
Percutaneous transcatheter hepatic artery embolization for liver cysts in autosomal dominant polycystic kidney disease.
Takei R, Ubara Y, Hoshino J, Higa Y, Suwabe T, Sogawa Y, Nomura K, Nakanishi S, Sawa N, Katori H, Takemoto F, Hara S, Takaichi K
Am J Kidney Dis 2007 Jun;49(6):744-52. doi: 10.1053/j.ajkd.2007.03.018. PMID: 17533017
Fatal, complete splenic infarction and hepatic infection due to disseminated Trichosporon beigelii infection: CT findings.
Viscomi SG, Mortelé KJ, Cantisani V, Glickman J, Silverman SG
Abdom Imaging 2004 Mar-Apr;29(2):228-30. doi: 10.1007/s00261-003-0099-6. PMID: 15290951
High prevalence of HCV infection among the general population in a rural area of central Italy.
Raffaele A, Valenti M, Iovenitti M, Matani A, Bruno ML, Altobelli E, D'Alessandro A, Barnabei R, Leonardis B, Taglieri G
Eur J Epidemiol 2001;17(1):41-6. doi: 10.1023/a:1010932832190. PMID: 11523574
Amebic liver abscess: epidemiology, clinical features, and outcome.
Seeto RK, Rockey DC
West J Med 1999 Feb;170(2):104-9. PMID: 10063397Free PMC Article

Clinical prediction guides

Flexible 3D Cell-Based Platforms for the Discovery and Profiling of Novel Drugs Targeting Plasmodium Hepatic Infection.
Arez F, Rebelo SP, Fontinha D, Simão D, Martins TR, Machado M, Fischli C, Oeuvray C, Badolo L, Carrondo MJT, Rottmann M, Spangenberg T, Brito C, Greco B, Prudêncio M, Alves PM
ACS Infect Dis 2019 Nov 8;5(11):1831-1842. Epub 2019 Sep 13 doi: 10.1021/acsinfecdis.9b00144. PMID: 31479238
Inhibition of Plasmodium Hepatic Infection by Antiretroviral Compounds.
Machado M, Sanches-Vaz M, Cruz JP, Mendes AM, Prudêncio M
Front Cell Infect Microbiol 2017;7:329. Epub 2017 Jul 19 doi: 10.3389/fcimb.2017.00329. PMID: 28770176Free PMC Article
Host AMPK Is a Modulator of Plasmodium Liver Infection.
Ruivo MTG, Vera IM, Sales-Dias J, Meireles P, Gural N, Bhatia SN, Mota MM, Mancio-Silva L
Cell Rep 2016 Sep 6;16(10):2539-2545. Epub 2016 Aug 25 doi: 10.1016/j.celrep.2016.08.001. PMID: 27568570Free PMC Article
Time to blood culture positivity as a predictor of clinical outcome of Staphylococcus aureus bloodstream infection.
Marra AR, Edmond MB, Forbes BA, Wenzel RP, Bearman GM
J Clin Microbiol 2006 Apr;44(4):1342-6. doi: 10.1128/JCM.44.4.1342-1346.2006. PMID: 16597860Free PMC Article
Prevalence of chronic hepatitis C virus genotypes among patients between 21 to 65 years old in Puerto Rico.
Rodríguez-Pérez F, Suárez-Pérez E, Alvarez-Rohena M, Toro DH
P R Health Sci J 2004 Jun;23(2 Suppl):49-56. PMID: 16929587

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