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Gonococcal Infection of Genitourinary Tract

MedGen UID:: 208895
•Concept ID:: C0854337
•: Disease or Syndrome

Definition

A genitourinary infection that is caused by Neisseria gonorrhoeae. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVGonococcal Infection of Genitourinary Tract

Clinical finding
- Finding by Cause
  - Infection
    - Bacterial Infections and Mycoses
      - Bacterial infectious disease
        Gonorrhea
        Gonococcal Infection of Genitourinary Tract
        Acute Gonococcal Infection of Lower Genitourinary Tract
        Acute Gonococcal Infection of Upper Genitourinary Tract

Professional guidelines

PubMed

Outpatient sexually transmitted infection testing and treatment patterns in the United States: a real-world database study.

Lillis R, Kuritzky L, Huynh Z, Arcenas R, Hansra A, Shah R, Yang B, Taylor SN
BMC Infect Dis 2023 Jul 13;23(1):469. doi: 10.1186/s12879-023-08434-2. PMID: 37442964 Free PMC Article

Gepotidacin: a novel, oral, 'first-in-class' triazaacenaphthylene antibiotic for the treatment of uncomplicated urinary tract infections and urogenital gonorrhoea.

Watkins RR, Thapaliya D, Lemonovich TL, Bonomo RA
J Antimicrob Chemother 2023 May 3;78(5):1137-1142. doi: 10.1093/jac/dkad060. PMID: 36883591

Common Bacterial and Viral Infections: Review of Management in the Pregnant Patient.

Rac H, Gould AP, Eiland LS, Griffin B, McLaughlin M, Stover KR, Bland CM, Bookstaver PB
Ann Pharmacother 2019 Jun;53(6):639-651. Epub 2018 Dec 17 doi: 10.1177/1060028018817935. PMID: 30556401

See all (102)

Recent clinical studies

Etiology

Etiology and Diagnosis of Pelvic Inflammatory Disease: Looking Beyond Gonorrhea and Chlamydia.

Mitchell CM, Anyalechi GE, Cohen CR, Haggerty CL, Manhart LE, Hillier SL
J Infect Dis 2021 Aug 16;224(12 Suppl 2):S29-S35. doi: 10.1093/infdis/jiab067. PMID: 34396407 Free PMC Article

Bacterial vaginosis-A brief synopsis of the literature.

Coudray MS, Madhivanan P
Eur J Obstet Gynecol Reprod Biol 2020 Feb;245:143-148. Epub 2019 Dec 24 doi: 10.1016/j.ejogrb.2019.12.035. PMID: 31901667 Free PMC Article

Infections During Pregnancy.

Leeper C, Lutzkanin A 3rd
Prim Care 2018 Sep;45(3):567-586. Epub 2018 Jul 9 doi: 10.1016/j.pop.2018.05.013. PMID: 30115342

The diagnosis of chronic endometritis in infertile asymptomatic women: a comparative study of histology, microbial cultures, hysteroscopy, and molecular microbiology.

Moreno I, Cicinelli E, Garcia-Grau I, Gonzalez-Monfort M, Bau D, Vilella F, De Ziegler D, Resta L, Valbuena D, Simon C
Am J Obstet Gynecol 2018 Jun;218(6):602.e1-602.e16. Epub 2018 Feb 23 doi: 10.1016/j.ajog.2018.02.012. PMID: 29477653

Periurethral abscess.

Walther MM, Mann BB, Finnerty DP
J Urol 1987 Nov;138(5):1167-70. doi: 10.1016/s0022-5347(17)43538-5. PMID: 3669161

See all (492)

Diagnosis

Etiology and Diagnosis of Pelvic Inflammatory Disease: Looking Beyond Gonorrhea and Chlamydia.

Mitchell CM, Anyalechi GE, Cohen CR, Haggerty CL, Manhart LE, Hillier SL
J Infect Dis 2021 Aug 16;224(12 Suppl 2):S29-S35. doi: 10.1093/infdis/jiab067. PMID: 34396407 Free PMC Article

Infections During Pregnancy.

Leeper C, Lutzkanin A 3rd
Prim Care 2018 Sep;45(3):567-586. Epub 2018 Jul 9 doi: 10.1016/j.pop.2018.05.013. PMID: 30115342

Gonococcal arthritis.

Bardin T
Best Pract Res Clin Rheumatol 2003 Apr;17(2):201-8. doi: 10.1016/s1521-6942(02)00125-0. PMID: 12787521

Pediatric vulvovaginitis.

Altchek A
J Reprod Med 1984 Jun;29(6):359-75. PMID: 6747969

Urethral stricture.

Bewes PC
Trop Doct 1973 Apr;3(2):77-81. doi: 10.1177/004947557300300208. PMID: 4691433

See all (705)

Therapy

Gepotidacin: a novel, oral, 'first-in-class' triazaacenaphthylene antibiotic for the treatment of uncomplicated urinary tract infections and urogenital gonorrhoea.

Watkins RR, Thapaliya D, Lemonovich TL, Bonomo RA
J Antimicrob Chemother 2023 May 3;78(5):1137-1142. doi: 10.1093/jac/dkad060. PMID: 36883591

The vaginal microbiota and its association with human papillomavirus, Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium infections: a systematic review and meta-analysis.

Tamarelle J, Thiébaut ACM, de Barbeyrac B, Bébéar C, Ravel J, Delarocque-Astagneau E
Clin Microbiol Infect 2019 Jan;25(1):35-47. Epub 2018 May 3 doi: 10.1016/j.cmi.2018.04.019. PMID: 29729331 Free PMC Article

Gonococcal arthritis.

Bardin T
Best Pract Res Clin Rheumatol 2003 Apr;17(2):201-8. doi: 10.1016/s1521-6942(02)00125-0. PMID: 12787521

Ofloxacin.

Tunkel AR, Scheld WM
Infect Control Hosp Epidemiol 1991 Sep;12(9):549-57. doi: 10.1086/646408. PMID: 1940278

Doxycycline.

Cunha BA, Sibley CM, Ristuccia AM
Ther Drug Monit 1982;4(2):115-35. doi: 10.1097/00007691-198206000-00001. PMID: 7048645

See all (413)

Prognosis

Bacterial vaginosis-A brief synopsis of the literature.

Coudray MS, Madhivanan P
Eur J Obstet Gynecol Reprod Biol 2020 Feb;245:143-148. Epub 2019 Dec 24 doi: 10.1016/j.ejogrb.2019.12.035. PMID: 31901667 Free PMC Article

Pathogenesis of Neisseria gonorrhoeae and the Host Defense in Ascending Infections of Human Fallopian Tube.

Lenz JD, Dillard JP
Front Immunol 2018;9:2710. Epub 2018 Nov 21 doi: 10.3389/fimmu.2018.02710. PMID: 30524442 Free PMC Article

The diagnosis of chronic endometritis in infertile asymptomatic women: a comparative study of histology, microbial cultures, hysteroscopy, and molecular microbiology.

Infectious arthritis.

Smith JW
Infect Dis Clin North Am 1990 Sep;4(3):523-38. PMID: 2212604

Periurethral abscess.

Walther MM, Mann BB, Finnerty DP
J Urol 1987 Nov;138(5):1167-70. doi: 10.1016/s0022-5347(17)43538-5. PMID: 3669161

See all (195)

Clinical prediction guides

Gonococcal Pelvic Inflammatory Disease: Placing Mechanistic Insights Into the Context of Clinical and Epidemiological Observations.

Xu SX, Gray-Owen SD
J Infect Dis 2021 Aug 16;224(12 Suppl 2):S56-S63. doi: 10.1093/infdis/jiab227. PMID: 34396410 Free PMC Article

Prevalence and Clinical Manifestations of Penile Gonococcal Cutaneous and Accessory Gland Infections in Men With Gonorrhea.

Fan W, Zhang Q, Zhang J, Fan Z, Jiang T
Sex Transm Dis 2021 Oct 1;48(10):781-786. doi: 10.1097/OLQ.0000000000001413. PMID: 34110739

The vaginal microbiota and its association with human papillomavirus, Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium infections: a systematic review and meta-analysis.

The diagnosis of chronic endometritis in infertile asymptomatic women: a comparative study of histology, microbial cultures, hysteroscopy, and molecular microbiology.

Infectious arthritis.

Smith JW
Infect Dis Clin North Am 1990 Sep;4(3):523-38. PMID: 2212604

See all (280)

Recent systematic reviews

Association of mycoplasma with prostate cancer: A systematic review and meta-analysis.

Tantengco OAG, Aquino IMC, de Castro Silva M, Rojo RD, Abad CLR
Cancer Epidemiol 2021 Dec;75:102021. Epub 2021 Sep 10 doi: 10.1016/j.canep.2021.102021. PMID: 34517226

Modulation effect of vaginal mucosal microflora and susceptibility to Neisseria gonorrhoeae infections: a systematic review and meta-analysis.

Zeng J, Yang R, He W, Zhong X, Liu W, Zhu H, Zhang X, Luo Q
Arch Gynecol Obstet 2019 Aug;300(2):261-267. Epub 2019 Jun 7 doi: 10.1007/s00404-019-05200-1. PMID: 31175401

The vaginal microbiota and its association with human papillomavirus, Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium infections: a systematic review and meta-analysis.

The effect of genital tract infections on HIV-1 shedding in the genital tract: a systematic review and meta-analysis.

Johnson LF, Lewis DA
Sex Transm Dis 2008 Nov;35(11):946-59. doi: 10.1097/OLQ.0b013e3181812d15. PMID: 18685546

Intrauterine device and upper-genital-tract infection.

Grimes DA
Lancet 2000 Sep 16;356(9234):1013-9. doi: 10.1016/S0140-6736(00)02699-4. PMID: 11041414

See all (9)