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Pleural Infection

MedGen UID:
214712
•Concept ID:
C0919907
•
Disease or Syndrome

Definition

An infectious process affecting the pleura. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPleural Infection

Professional guidelines

PubMed

ERS/ESTS statement on the management of pleural infection in adults.
Bedawi EO, Ricciardi S, Hassan M, Gooseman MR, Asciak R, Castro-Añón O, Armbruster K, Bonifazi M, Poole S, Harris EK, Elia S, Krenke R, Mariani A, Maskell NA, Polverino E, Porcel JM, Yarmus L, Belcher EP, Opitz I, Rahman NM
Eur Respir J 2023 Feb;61(2) Epub 2023 Feb 2 doi: 10.1183/13993003.01062-2022. PMID: 36229045
Management of post-hepatectomy complications.
Jin S, Fu Q, Wuyun G, Wuyun T
World J Gastroenterol 2013 Nov 28;19(44):7983-91. doi: 10.3748/wjg.v19.i44.7983. PMID: 24307791Free PMC Article
Management of pleural infection in adults: British Thoracic Society Pleural Disease Guideline 2010.
Davies HE, Davies RJ, Davies CW; BTS Pleural Disease Guideline Group
Thorax 2010 Aug;65 Suppl 2:ii41-53. doi: 10.1136/thx.2010.137000. PMID: 20696693

Recent clinical studies

Etiology

Parapneumonic Effusion and Empyema.
Addala DN, Bedawi EO, Rahman NM
Clin Chest Med 2021 Dec;42(4):637-647. doi: 10.1016/j.ccm.2021.08.001. PMID: 34774171
Tuberculous pleural effusion.
Shaw JA, Diacon AH, Koegelenberg CFN
Respirology 2019 Oct;24(10):962-971. Epub 2019 Aug 16 doi: 10.1111/resp.13673. PMID: 31418985
A clinical score (RAPID) to identify those at risk for poor outcome at presentation in patients with pleural infection.
Rahman NM, Kahan BC, Miller RF, Gleeson FV, Nunn AJ, Maskell NA
Chest 2014 Apr;145(4):848-855. doi: 10.1378/chest.13-1558. PMID: 24264558
Intrapleural use of tissue plasminogen activator and DNase in pleural infection.
Rahman NM, Maskell NA, West A, Teoh R, Arnold A, Mackinlay C, Peckham D, Davies CW, Ali N, Kinnear W, Bentley A, Kahan BC, Wrightson JM, Davies HE, Hooper CE, Lee YC, Hedley EL, Crosthwaite N, Choo L, Helm EJ, Gleeson FV, Nunn AJ, Davies RJ
N Engl J Med 2011 Aug 11;365(6):518-26. doi: 10.1056/NEJMoa1012740. PMID: 21830966
Management of pleural infection in adults: British Thoracic Society Pleural Disease Guideline 2010.
Davies HE, Davies RJ, Davies CW; BTS Pleural Disease Guideline Group
Thorax 2010 Aug;65 Suppl 2:ii41-53. doi: 10.1136/thx.2010.137000. PMID: 20696693

Diagnosis

ERS/ESTS statement on the management of pleural infection in adults.
Bedawi EO, Ricciardi S, Hassan M, Gooseman MR, Asciak R, Castro-Añón O, Armbruster K, Bonifazi M, Poole S, Harris EK, Elia S, Krenke R, Mariani A, Maskell NA, Polverino E, Porcel JM, Yarmus L, Belcher EP, Opitz I, Rahman NM
Eur Respir J 2023 Feb;61(2) Epub 2023 Feb 2 doi: 10.1183/13993003.01062-2022. PMID: 36229045
Parapneumonic Effusion and Empyema.
Addala DN, Bedawi EO, Rahman NM
Clin Chest Med 2021 Dec;42(4):637-647. doi: 10.1016/j.ccm.2021.08.001. PMID: 34774171
Tuberculous pleural effusion.
Shaw JA, Diacon AH, Koegelenberg CFN
Respirology 2019 Oct;24(10):962-971. Epub 2019 Aug 16 doi: 10.1111/resp.13673. PMID: 31418985
A clinical score (RAPID) to identify those at risk for poor outcome at presentation in patients with pleural infection.
Rahman NM, Kahan BC, Miller RF, Gleeson FV, Nunn AJ, Maskell NA
Chest 2014 Apr;145(4):848-855. doi: 10.1378/chest.13-1558. PMID: 24264558
Management of pleural infection in adults: British Thoracic Society Pleural Disease Guideline 2010.
Davies HE, Davies RJ, Davies CW; BTS Pleural Disease Guideline Group
Thorax 2010 Aug;65 Suppl 2:ii41-53. doi: 10.1136/thx.2010.137000. PMID: 20696693

Therapy

Early Video-assisted Thoracoscopic Surgery or Intrapleural Enzyme Therapy in Pleural Infection: A Feasibility Randomized Controlled Trial. The Third Multicenter Intrapleural Sepsis Trial-MIST-3.
Bedawi EO, Stavroulias D, Hedley E, Blyth KG, Kirk A, De Fonseka D, Edwards JG, Internullo E, Corcoran JP, Marchbank A, Panchal R, Caruana E, Kadwani O, Okiror L, Saba T, Purohit M, Mercer RM, Taberham R, Kanellakis N, Condliffe AM, Lewis LG, Addala DN, Asciak R, Banka R, George V, Hassan M, McCracken D, Sundaralingam A, Wrightson JM, Dobson M, West A, Barnes G, Harvey J, Slade M, Chester-Jones M, Dutton S, Miller RF, Maskell NA, Belcher E, Rahman NM
Am J Respir Crit Care Med 2023 Dec 15;208(12):1305-1315. doi: 10.1164/rccm.202305-0854OC. PMID: 37820359Free PMC Article
Parapneumonic Effusion and Empyema.
Addala DN, Bedawi EO, Rahman NM
Clin Chest Med 2021 Dec;42(4):637-647. doi: 10.1016/j.ccm.2021.08.001. PMID: 34774171
Tuberculous pleural effusion.
Shaw JA, Diacon AH, Koegelenberg CFN
Respirology 2019 Oct;24(10):962-971. Epub 2019 Aug 16 doi: 10.1111/resp.13673. PMID: 31418985
Intrapleural use of tissue plasminogen activator and DNase in pleural infection.
Rahman NM, Maskell NA, West A, Teoh R, Arnold A, Mackinlay C, Peckham D, Davies CW, Ali N, Kinnear W, Bentley A, Kahan BC, Wrightson JM, Davies HE, Hooper CE, Lee YC, Hedley EL, Crosthwaite N, Choo L, Helm EJ, Gleeson FV, Nunn AJ, Davies RJ
N Engl J Med 2011 Aug 11;365(6):518-26. doi: 10.1056/NEJMoa1012740. PMID: 21830966
Management of pleural infection in adults: British Thoracic Society Pleural Disease Guideline 2010.
Davies HE, Davies RJ, Davies CW; BTS Pleural Disease Guideline Group
Thorax 2010 Aug;65 Suppl 2:ii41-53. doi: 10.1136/thx.2010.137000. PMID: 20696693

Prognosis

ERS/ESTS statement on the management of pleural infection in adults.
Bedawi EO, Ricciardi S, Hassan M, Gooseman MR, Asciak R, Castro-Añón O, Armbruster K, Bonifazi M, Poole S, Harris EK, Elia S, Krenke R, Mariani A, Maskell NA, Polverino E, Porcel JM, Yarmus L, Belcher EP, Opitz I, Rahman NM
Eur Respir J 2023 Feb;61(2) Epub 2023 Feb 2 doi: 10.1183/13993003.01062-2022. PMID: 36229045
Emerging concepts in pleural infection.
Chan KP, Fitzgerald DB, Lee YCG
Curr Opin Pulm Med 2018 Jul;24(4):367-373. doi: 10.1097/MCP.0000000000000487. PMID: 29538080
Advances in pleuroscopy.
Anevlavis S, Froudarakis ME
Clin Respir J 2018 Mar;12(3):839-847. Epub 2017 Jan 11 doi: 10.1111/crj.12597. PMID: 27997741
A clinical score (RAPID) to identify those at risk for poor outcome at presentation in patients with pleural infection.
Rahman NM, Kahan BC, Miller RF, Gleeson FV, Nunn AJ, Maskell NA
Chest 2014 Apr;145(4):848-855. doi: 10.1378/chest.13-1558. PMID: 24264558
Management of pleural infection in adults: British Thoracic Society Pleural Disease Guideline 2010.
Davies HE, Davies RJ, Davies CW; BTS Pleural Disease Guideline Group
Thorax 2010 Aug;65 Suppl 2:ii41-53. doi: 10.1136/thx.2010.137000. PMID: 20696693

Clinical prediction guides

ERS/ESTS statement on the management of pleural infection in adults.
Bedawi EO, Ricciardi S, Hassan M, Gooseman MR, Asciak R, Castro-Añón O, Armbruster K, Bonifazi M, Poole S, Harris EK, Elia S, Krenke R, Mariani A, Maskell NA, Polverino E, Porcel JM, Yarmus L, Belcher EP, Opitz I, Rahman NM
Eur Respir J 2023 Feb;61(2) Epub 2023 Feb 2 doi: 10.1183/13993003.01062-2022. PMID: 36229045
Advances in pleuroscopy.
Anevlavis S, Froudarakis ME
Clin Respir J 2018 Mar;12(3):839-847. Epub 2017 Jan 11 doi: 10.1111/crj.12597. PMID: 27997741
A clinical score (RAPID) to identify those at risk for poor outcome at presentation in patients with pleural infection.
Rahman NM, Kahan BC, Miller RF, Gleeson FV, Nunn AJ, Maskell NA
Chest 2014 Apr;145(4):848-855. doi: 10.1378/chest.13-1558. PMID: 24264558
Intrapleural use of tissue plasminogen activator and DNase in pleural infection.
Rahman NM, Maskell NA, West A, Teoh R, Arnold A, Mackinlay C, Peckham D, Davies CW, Ali N, Kinnear W, Bentley A, Kahan BC, Wrightson JM, Davies HE, Hooper CE, Lee YC, Hedley EL, Crosthwaite N, Choo L, Helm EJ, Gleeson FV, Nunn AJ, Davies RJ
N Engl J Med 2011 Aug 11;365(6):518-26. doi: 10.1056/NEJMoa1012740. PMID: 21830966
Imaging of the pleura.
Helm EJ, Matin TN, Gleeson FV
J Magn Reson Imaging 2010 Dec;32(6):1275-86. doi: 10.1002/jmri.22372. PMID: 21105134

Recent systematic reviews

Efficacy of Small versus Large-Bore Chest Drain in Pleural Infection: A Systematic Review and Meta-Analysis.
Mei F, Rota M, Bonifazi M, Zuccatosta L, Porcarelli FM, Sediari M, Bedawi EO, Sundaralingam A, Addala D, Gasparini S, Rahman NM
Respiration 2023;102(3):247-256. Epub 2023 Jan 24 doi: 10.1159/000529027. PMID: 36693327
Clinical relevance of molecular testing methods in the diagnosis and guidance of therapy in patients with staphylococcal empyema: a systematic review and meta-analysis.
Ojha SC, Chen K, Yuan Y, Ahmed S, Malik AA, Nisha M, Sheng YJ, Sun C, Wu G, Deng CL
Front Cell Infect Microbiol 2022;12:758833. Epub 2022 Jul 29 doi: 10.3389/fcimb.2022.758833. PMID: 35967859Free PMC Article
Intra-pleural fibrinolytic therapy versus placebo, or a different fibrinolytic agent, in the treatment of adult parapneumonic effusions and empyema.
Altmann ES, Crossingham I, Wilson S, Davies HR
Cochrane Database Syst Rev 2019 Oct 30;2019(10) doi: 10.1002/14651858.CD002312.pub4. PMID: 31684683Free PMC Article
A systematic review of comorbidities and outcomes of adult patients with pleural infection.
Cargill TN, Hassan M, Corcoran JP, Harriss E, Asciak R, Mercer RM, McCracken DJ, Bedawi EO, Rahman NM
Eur Respir J 2019 Sep;54(3) Epub 2019 Oct 1 doi: 10.1183/13993003.00541-2019. PMID: 31391221Free PMC Article
The microbiology of pleural infection in adults: a systematic review.
Hassan M, Cargill T, Harriss E, Asciak R, Mercer RM, Bedawi EO, McCracken DJ, Psallidas I, Corcoran JP, Rahman NM
Eur Respir J 2019 Sep;54(3) Epub 2019 Oct 1 doi: 10.1183/13993003.00542-2019. PMID: 31248959

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