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Fundic Gland Polyp

MedGen UID:
214715
Concept ID:
C0920184
Neoplastic Process
Synonym: Polyps, fundic gland
SNOMED CT: Fundic gland polyp (447420007)

Definition

The most common gastric polyp in the Western hemisphere. The lesion consists of a localized hyperplasia of the deep epithelial compartment of the oxyntic mucosa, with variable degrees of cystic dilatation. Malignant transformation is the exception. (WHO, 2000) [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFundic Gland Polyp

Professional guidelines

PubMed

Castro R, Pimentel-Nunes P, Dinis-Ribeiro M
Best Pract Res Clin Gastroenterol 2017 Aug;31(4):381-387. Epub 2017 Jun 13 doi: 10.1016/j.bpg.2017.06.001. PMID: 28842047
Schmocker RK, Lidor AO
Surg Clin North Am 2017 Apr;97(2):387-403. doi: 10.1016/j.suc.2016.11.011. PMID: 28325193

Recent clinical studies

Etiology

Amarapurkar AD, Kale KM, Naik LP, Shukla AP
Indian J Pathol Microbiol 2021 Jun;64(Supplement):S69-S72. doi: 10.4103/IJPM.IJPM_118_20. PMID: 34135141
Tacheci I, Repak R, Podhola M, Benesova L, Cyrany J, Bures J, Kohoutova D
Best Pract Res Clin Gastroenterol 2021 Mar-Apr;50-51:101728. Epub 2021 Feb 15 doi: 10.1016/j.bpg.2021.101728. PMID: 33975682
Notsu T, Adachi K, Mishiro T, Ishimura N, Ishihara S
J Gastroenterol Hepatol 2020 Jul;35(7):1158-1162. Epub 2019 Dec 31 doi: 10.1111/jgh.14934. PMID: 31734951
Velazquez-Dohorn M, López-Durand CF, Candanedo-González F, Araujo-Villalvazo EA, Gamboa-Domínguez A
Rev Gastroenterol Mex (Engl Ed) 2020 Jan-Mar;85(1):42-47. Epub 2019 May 22 doi: 10.1016/j.rgmx.2019.02.007. PMID: 31126726
Martin FC, Chenevix-Trench G, Yeomans ND
Aliment Pharmacol Ther 2016 Nov;44(9):915-925. Epub 2016 Sep 15 doi: 10.1111/apt.13800. PMID: 27634363

Diagnosis

Tacheci I, Repak R, Podhola M, Benesova L, Cyrany J, Bures J, Kohoutova D
Best Pract Res Clin Gastroenterol 2021 Mar-Apr;50-51:101728. Epub 2021 Feb 15 doi: 10.1016/j.bpg.2021.101728. PMID: 33975682
Velazquez-Dohorn M, López-Durand CF, Candanedo-González F, Araujo-Villalvazo EA, Gamboa-Domínguez A
Rev Gastroenterol Mex (Engl Ed) 2020 Jan-Mar;85(1):42-47. Epub 2019 May 22 doi: 10.1016/j.rgmx.2019.02.007. PMID: 31126726
Velázquez-Dohorn ME, López-Durand CF, Gamboa-Domínguez A
Rev Invest Clin 2018;70(1):40-45. doi: 10.24875/RIC.17002430. PMID: 29513301
Castro R, Pimentel-Nunes P, Dinis-Ribeiro M
Best Pract Res Clin Gastroenterol 2017 Aug;31(4):381-387. Epub 2017 Jun 13 doi: 10.1016/j.bpg.2017.06.001. PMID: 28842047
Schmocker RK, Lidor AO
Surg Clin North Am 2017 Apr;97(2):387-403. doi: 10.1016/j.suc.2016.11.011. PMID: 28325193

Therapy

Coyne JD, Thampy S
Int J Surg Pathol 2021 Aug;29(5):503-505. Epub 2021 Apr 7 doi: 10.1177/1066896921994183. PMID: 33827319
Velazquez-Dohorn M, López-Durand CF, Candanedo-González F, Araujo-Villalvazo EA, Gamboa-Domínguez A
Rev Gastroenterol Mex (Engl Ed) 2020 Jan-Mar;85(1):42-47. Epub 2019 May 22 doi: 10.1016/j.rgmx.2019.02.007. PMID: 31126726
Fukuda M, Ishigaki H, Sugimoto M, Mukaisho KI, Matsubara A, Ishida H, Moritani S, Itoh Y, Sugihara H, Andoh A, Ogasawara K, Murakami K, Kushima R
Histopathology 2019 Oct;75(4):537-545. Epub 2019 Aug 2 doi: 10.1111/his.13902. PMID: 31087669
Takeda T, Asaoka D, Tajima Y, Matsumoto K, Takeda N, Hiromoto T, Okubo S, Saito H, Aoyama T, Shibuya T, Sakamoto N, Hojo M, Osada T, Nagahara A, Yao T, Watanabe S
Clin J Gastroenterol 2017 Oct;10(5):478-484. Epub 2017 Jun 28 doi: 10.1007/s12328-017-0756-x. PMID: 28660530Free PMC Article
Martin FC, Chenevix-Trench G, Yeomans ND
Aliment Pharmacol Ther 2016 Nov;44(9):915-925. Epub 2016 Sep 15 doi: 10.1111/apt.13800. PMID: 27634363

Prognosis

Dutta AK, Uedo N, David D, Chandramohan J, Jain A, Patnayak I, Gupta P, Ayapati BK, Chatterjee K, Jaleel R, Kurien RT, Chowdhury SD, Simon EG, Joseph AJ, Pulimood AB
Indian J Gastroenterol 2022 Dec;41(6):599-609. Epub 2022 Dec 23 doi: 10.1007/s12664-022-01278-9. PMID: 36562941
Brito HLF, Barros C, Freire MV, Silva Filho MND, Nascimento TV
Arq Gastroenterol 2018 Oct-Dec;55(4):380-384. doi: 10.1590/S0004-2803.201800000-82. PMID: 30785522
Yamaguchi T, Ishida H, Ueno H, Kobayashi H, Hinoi T, Inoue Y, Ishida F, Kanemitsu Y, Konishi T, Tomita N, Matsubara N, Watanabe T, Sugihara K
Jpn J Clin Oncol 2016 Apr;46(4):310-5. Epub 2016 Jan 26 doi: 10.1093/jjco/hyv210. PMID: 26819281Free PMC Article
Hongo M, Fujimoto K; Gastric Polyps Study Group
J Gastroenterol 2010 Jun;45(6):618-24. Epub 2010 Feb 23 doi: 10.1007/s00535-010-0207-7. PMID: 20177714
Teichmann J, Weickert U, Riemann JF
Eur J Med Res 2008 May 26;13(5):192-5. PMID: 18559299

Clinical prediction guides

Dutta AK, Uedo N, David D, Chandramohan J, Jain A, Patnayak I, Gupta P, Ayapati BK, Chatterjee K, Jaleel R, Kurien RT, Chowdhury SD, Simon EG, Joseph AJ, Pulimood AB
Indian J Gastroenterol 2022 Dec;41(6):599-609. Epub 2022 Dec 23 doi: 10.1007/s12664-022-01278-9. PMID: 36562941
Sato Y, Ban S, Katayama Y, Mitsui T
Hum Pathol 2022 Jul;125:23-34. Epub 2022 Apr 14 doi: 10.1016/j.humpath.2022.04.001. PMID: 35430166
Orr CE, Beneck D, Jessurun J, Qin L, Tyryshkin K, Yantiss RK, Chen YT
Histopathology 2022 Jan;80(2):314-321. Epub 2021 Oct 13 doi: 10.1111/his.14549. PMID: 34424570
Nonaka S, Hashimoto T, Oda I, Sekine S
Gastric Cancer 2020 Nov;23(6):1102-1106. Epub 2020 May 15 doi: 10.1007/s10120-020-01082-4. PMID: 32415517
Velázquez-Dohorn ME, López-Durand CF, Gamboa-Domínguez A
Rev Invest Clin 2018;70(1):40-45. doi: 10.24875/RIC.17002430. PMID: 29513301

Recent systematic reviews

Martin FC, Chenevix-Trench G, Yeomans ND
Aliment Pharmacol Ther 2016 Nov;44(9):915-925. Epub 2016 Sep 15 doi: 10.1111/apt.13800. PMID: 27634363

Supplemental Content

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