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Transient organic mental disorder

MedGen UID:
21769
•Concept ID:
C0041891
•
Mental or Behavioral Dysfunction
Synonym: Transient Organic Mental Disorder
SNOMED CT: Transient organic mental disorder (428703001)

Definition

An organic mental disorder that is temporary in nature. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTransient organic mental disorder

Professional guidelines

PubMed

Detection and Management of Amyloid-Related Imaging Abnormalities in Patients with Alzheimer's Disease Treated with Anti-Amyloid Beta Therapy.
Barakos J, Purcell D, Suhy J, Chalkias S, Burkett P, Marsica Grassi C, Castrillo-Viguera C, Rubino I, Vijverberg E
J Prev Alzheimers Dis 2022;9(2):211-220. doi: 10.14283/jpad.2022.21. PMID: 35542992
Management of concussion in soccer.
Hubertus V, Marklund N, Vajkoczy P
Acta Neurochir (Wien) 2019 Mar;161(3):425-433. Epub 2019 Jan 28 doi: 10.1007/s00701-019-03807-6. PMID: 30687899
Acute Brain Failure: Pathophysiology, Diagnosis, Management, and Sequelae of Delirium.
Maldonado JR
Crit Care Clin 2017 Jul;33(3):461-519. doi: 10.1016/j.ccc.2017.03.013. PMID: 28601132

Recent clinical studies

Etiology

Cognitive Decline in Early and Premature Menopause.
Sochocka M, Karska J, Pszczołowska M, Ochnik M, Fułek M, Fułek K, Kurpas D, Chojdak-Łukasiewicz J, Rosner-Tenerowicz A, Leszek J
Int J Mol Sci 2023 Mar 31;24(7) doi: 10.3390/ijms24076566. PMID: 37047549Free PMC Article
Postoperative cognitive dysfunction - current preventive strategies.
Kotekar N, Shenkar A, Nagaraj R
Clin Interv Aging 2018;13:2267-2273. Epub 2018 Nov 8 doi: 10.2147/CIA.S133896. PMID: 30519008Free PMC Article
Acute Brain Failure: Pathophysiology, Diagnosis, Management, and Sequelae of Delirium.
Maldonado JR
Crit Care Clin 2017 Jul;33(3):461-519. doi: 10.1016/j.ccc.2017.03.013. PMID: 28601132
Stroke injury, cognitive impairment and vascular dementia.
Kalaria RN, Akinyemi R, Ihara M
Biochim Biophys Acta 2016 May;1862(5):915-25. Epub 2016 Jan 22 doi: 10.1016/j.bbadis.2016.01.015. PMID: 26806700Free PMC Article
Iodine deficiency.
Zimmermann MB
Endocr Rev 2009 Jun;30(4):376-408. Epub 2009 May 21 doi: 10.1210/er.2009-0011. PMID: 19460960

Diagnosis

Transient Global Amnesia.
Ropper AH
N Engl J Med 2023 Feb 16;388(7):635-640. doi: 10.1056/NEJMra2213867. PMID: 36791163
Acute-onset amnesia: transient global amnesia and other causes.
Miller TD, Butler CR
Pract Neurol 2022 Jun;22(3):201-208. Epub 2022 May 3 doi: 10.1136/practneurol-2020-002826. PMID: 35504698
Acute Brain Failure: Pathophysiology, Diagnosis, Management, and Sequelae of Delirium.
Maldonado JR
Crit Care Clin 2017 Jul;33(3):461-519. doi: 10.1016/j.ccc.2017.03.013. PMID: 28601132
Stroke injury, cognitive impairment and vascular dementia.
Kalaria RN, Akinyemi R, Ihara M
Biochim Biophys Acta 2016 May;1862(5):915-25. Epub 2016 Jan 22 doi: 10.1016/j.bbadis.2016.01.015. PMID: 26806700Free PMC Article
Young-onset dementia.
Kuruppu DK, Matthews BR
Semin Neurol 2013 Sep;33(4):365-85. Epub 2013 Nov 14 doi: 10.1055/s-0033-1359320. PMID: 24234358Free PMC Article

Therapy

Cognitive Decline in Early and Premature Menopause.
Sochocka M, Karska J, Pszczołowska M, Ochnik M, Fułek M, Fułek K, Kurpas D, Chojdak-Łukasiewicz J, Rosner-Tenerowicz A, Leszek J
Int J Mol Sci 2023 Mar 31;24(7) doi: 10.3390/ijms24076566. PMID: 37047549Free PMC Article
γ-Secretase in Alzheimer's disease.
Hur JY
Exp Mol Med 2022 Apr;54(4):433-446. Epub 2022 Apr 8 doi: 10.1038/s12276-022-00754-8. PMID: 35396575Free PMC Article
Postoperative cognitive dysfunction - current preventive strategies.
Kotekar N, Shenkar A, Nagaraj R
Clin Interv Aging 2018;13:2267-2273. Epub 2018 Nov 8 doi: 10.2147/CIA.S133896. PMID: 30519008Free PMC Article
Iodine deficiency.
Zimmermann MB
Endocr Rev 2009 Jun;30(4):376-408. Epub 2009 May 21 doi: 10.1210/er.2009-0011. PMID: 19460960
The effects of benzodiazepines on cognition.
Stewart SA
J Clin Psychiatry 2005;66 Suppl 2:9-13. PMID: 15762814

Prognosis

Acute-onset amnesia: transient global amnesia and other causes.
Miller TD, Butler CR
Pract Neurol 2022 Jun;22(3):201-208. Epub 2022 May 3 doi: 10.1136/practneurol-2020-002826. PMID: 35504698
Post-traumatic amnesia.
Parker TD, Rees R, Rajagopal S, Griffin C, Goodliffe L, Dilley M, Jenkins PO
Pract Neurol 2022 Apr;22(2):129-137. Epub 2021 Dec 14 doi: 10.1136/practneurol-2021-003056. PMID: 34906998
Insight across mental disorders: A multifaceted metacognitive phenomenon.
Konstantakopoulos G
Psychiatriki 2019 Jan-Mar;30(1):13-16. doi: 10.22365/jpsych.2019.301.13. PMID: 31115349
Transient global amnesia.
Arena JE, Rabinstein AA
Mayo Clin Proc 2015 Feb;90(2):264-72. doi: 10.1016/j.mayocp.2014.12.001. PMID: 25659242
Amnesic disorders.
Markowitsch HJ, Staniloiu A
Lancet 2012 Oct 20;380(9851):1429-40. Epub 2012 Apr 13 doi: 10.1016/S0140-6736(11)61304-4. PMID: 22503117

Clinical prediction guides

Evaluating the Safety and Efficacy of Crenezumab vs Placebo in Adults With Early Alzheimer Disease: Two Phase 3 Randomized Placebo-Controlled Trials.
Ostrowitzki S, Bittner T, Sink KM, Mackey H, Rabe C, Honig LS, Cassetta E, Woodward M, Boada M, van Dyck CH, Grimmer T, Selkoe DJ, Schneider A, Blondeau K, Hu N, Quartino A, Clayton D, Dolton M, Dang Y, Ostaszewski B, Sanabria-Bohórquez SM, Rabbia M, Toth B, Eichenlaub U, Smith J, Honigberg LA, Doody RS
JAMA Neurol 2022 Nov 1;79(11):1113-1121. doi: 10.1001/jamaneurol.2022.2909. PMID: 36121669Free PMC Article
Transient global amnesia: Model, mechanism, hypothesis.
Larner AJ
Cortex 2022 Apr;149:137-147. Epub 2022 Jan 31 doi: 10.1016/j.cortex.2022.01.011. PMID: 35228100
Impact of Donepezil and Memantine on Behavioral and Psychological Symptoms of Alzheimer Disease: Six-month Open-label Study.
Bago Rožanković P, Rožanković M, Badžak J, Stojić M, Šušak Sporiš I
Cogn Behav Neurol 2021 Dec 2;34(4):288-294. doi: 10.1097/WNN.0000000000000285. PMID: 34851866
Insight across mental disorders: A multifaceted metacognitive phenomenon.
Konstantakopoulos G
Psychiatriki 2019 Jan-Mar;30(1):13-16. doi: 10.22365/jpsych.2019.301.13. PMID: 31115349
Transient Global Amnesia: Emergency Department Evaluation And Management.
Faust JS, Nemes A
Emerg Med Pract 2016 Aug;18(8):1-20. Epub 2016 Aug 1 PMID: 27416582

Recent systematic reviews

Periodontal bacteria in the brain-Implication for Alzheimer's disease: A systematic review.
Parra-Torres V, Melgar-Rodríguez S, Muñoz-Manríquez C, Sanhueza B, Cafferata EA, Paula-Lima AC, Díaz-Zúñiga J
Oral Dis 2023 Jan;29(1):21-28. Epub 2021 Nov 10 doi: 10.1111/odi.14054. PMID: 34698406
Prevalence of Clinical and Neuroimaging Markers in Cerebral Amyloid Angiopathy: A Systematic Review and Meta-Analysis.
Malhotra K, Theodorou A, Katsanos AH, Zompola C, Shoamanesh A, Boviatsis E, Paraskevas GP, Spilioti M, Cordonnier C, Werring DJ, Alexandrov AV, Tsivgoulis G
Stroke 2022 Jun;53(6):1944-1953. Epub 2022 Mar 10 doi: 10.1161/STROKEAHA.121.035836. PMID: 35264008
Amyloid-Related Imaging Abnormalities and β-Amyloid-Targeting Antibodies: A Systematic Review.
Filippi M, Cecchetti G, Spinelli EG, Vezzulli P, Falini A, Agosta F
JAMA Neurol 2022 Mar 1;79(3):291-304. doi: 10.1001/jamaneurol.2021.5205. PMID: 35099507
Antipsychotics and the Risk of Cerebrovascular Accident: A Systematic Review and Meta-Analysis of Observational Studies.
Hsu WT, Esmaily-Fard A, Lai CC, Zala D, Lee SH, Chang SS, Lee CC
J Am Med Dir Assoc 2017 Aug 1;18(8):692-699. Epub 2017 Apr 18 doi: 10.1016/j.jamda.2017.02.020. PMID: 28431909
Psychiatric symptomatology after delirium: a systematic review.
Langan C, Sarode DP, Russ TC, Shenkin SD, Carson A, Maclullich AMJ
Psychogeriatrics 2017 Sep;17(5):327-335. Epub 2017 Jan 27 doi: 10.1111/psyg.12240. PMID: 28127828

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