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Gastric xanthoma

MedGen UID:
220915
•Concept ID:
C1282522
•
Disease or Syndrome
Synonyms: Gastric xanthelasma; Gastric Xanthelasma; Gastric Xanthoma; Gastric xanthomas; Gastric xanthomata; Xanthoma of Stomach; Xanthoma of the Stomach
SNOMED CT: Gastric xanthelasma (315057000)
 
HPO: HP:0034468

Definition

Gastric xanthomas (also known as xanthelasmas) are are plaque-like red lesions defined by the presence of histiocytic containing lipids. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGastric xanthoma

Professional guidelines

PubMed

Impact of Cyclooxygenase-2 1195 G-Carrier Genotype Associated with Intestinal Metaplasia and Endoscopic Findings Based on Kyoto Classification.
Kodaka Y, Futagami S, Tatsuguchi A, Yamawaki H, Sato H, Hashimoto S, Kawagoe T, Ueki N, Nagoya H, Maruki Y, Miyake K, Gudis K, Sakamoto C, Iwakiri K
Digestion 2017;96(3):173-183. Epub 2017 Sep 26 doi: 10.1159/000479864. PMID: 28946145

Recent clinical studies

Etiology

Relationship between gastric xanthoma, gastric precancerous lesions, and gastric cancer: A retrospective study.
Shen WN, Qu XD, Chen SS, Liu YH, Gao MJ, Shi YQ
J Dig Dis 2023 May;24(5):340-347. Epub 2023 Jul 28 doi: 10.1111/1751-2980.13202. PMID: 37417403
ABC Classification Is Less Useful for Older Koreans Born before 1960.
Kwon H, Lee SY, Kim JH, Lee SP, Kim JH, Sung IK, Park HS, Shim CS
Gut Liver 2019 Sep 15;13(5):522-530. doi: 10.5009/gnl18399. PMID: 30970432Free PMC Article
Gastric Xanthoma Is a Predictive Marker for Early Gastric Cancer Detected after Helicobacter pylori Eradication.
Shibukawa N, Ouchi S, Wakamatsu S, Wakahara Y, Kaneko A
Intern Med 2019 Mar 15;58(6):779-784. Epub 2018 Nov 19 doi: 10.2169/internalmedicine.0925-18. PMID: 30449773Free PMC Article
Non-gastric Gastrointestinal Xanthomas: Case Series and Literature Review.
Díaz Del Arco C, Álvarez Sánchez Á, Fernández Aceñero MJ
J Gastrointestin Liver Dis 2016 Sep;25(3):389-94. PMID: 27689205
A close relationship between Helicobacter pylori infection and gastric xanthoma.
Isomoto H, Mizuta Y, Inoue K, Matsuo T, Hayakawa T, Miyazaki M, Onita K, Takeshima F, Murase K, Shimokawa I, Kohno S
Scand J Gastroenterol 1999 Apr;34(4):346-52. doi: 10.1080/003655299750026344. PMID: 10365893

Diagnosis

Gastric Xanthoma: An Incidental and Unusual Finding.
Abu-Alreesh S, Rosen D, Nalbantoglu I, Arbizu RA
J Pediatr Gastroenterol Nutr 2021 Jul 1;73(1):e26. doi: 10.1097/MPG.0000000000003085. PMID: 33605661
Gastric Xanthoma Associated with Gastric Cancer Development: An Updated Review.
Moumin FA, Mohamed AA, Osman AA, Cai J
Can J Gastroenterol Hepatol 2020;2020:3578927. Epub 2020 Feb 21 doi: 10.1155/2020/3578927. PMID: 32149048Free PMC Article
Gastric Xanthoma Is a Predictive Marker for Early Gastric Cancer Detected after Helicobacter pylori Eradication.
Shibukawa N, Ouchi S, Wakamatsu S, Wakahara Y, Kaneko A
Intern Med 2019 Mar 15;58(6):779-784. Epub 2018 Nov 19 doi: 10.2169/internalmedicine.0925-18. PMID: 30449773Free PMC Article
Non-gastric Gastrointestinal Xanthomas: Case Series and Literature Review.
Díaz Del Arco C, Álvarez Sánchez Á, Fernández Aceñero MJ
J Gastrointestin Liver Dis 2016 Sep;25(3):389-94. PMID: 27689205
Gastric xanthoma.
Kunze KC, Baum RA, Nasrallah SM
Gastrointest Endosc 1987 Apr;33(2):114-5. doi: 10.1016/s0016-5107(87)71525-9. PMID: 3569789

Therapy

Gastric Xanthoma Is a Predictive Marker for Early Gastric Cancer Detected after Helicobacter pylori Eradication.
Shibukawa N, Ouchi S, Wakamatsu S, Wakahara Y, Kaneko A
Intern Med 2019 Mar 15;58(6):779-784. Epub 2018 Nov 19 doi: 10.2169/internalmedicine.0925-18. PMID: 30449773Free PMC Article

Prognosis

A Retroflexed View into the Metabolic Syndrome.
Hathorn KE, Najdawi F, Hamilton MJ
Gastroenterology 2020 Nov;159(5):e6-e7. Epub 2020 Apr 19 doi: 10.1053/j.gastro.2020.03.082. PMID: 32320691
Gastric Xanthoma Associated with Gastric Cancer Development: An Updated Review.
Moumin FA, Mohamed AA, Osman AA, Cai J
Can J Gastroenterol Hepatol 2020;2020:3578927. Epub 2020 Feb 21 doi: 10.1155/2020/3578927. PMID: 32149048Free PMC Article
Gastric Xanthoma Is a Predictive Marker for Early Gastric Cancer Detected after Helicobacter pylori Eradication.
Shibukawa N, Ouchi S, Wakamatsu S, Wakahara Y, Kaneko A
Intern Med 2019 Mar 15;58(6):779-784. Epub 2018 Nov 19 doi: 10.2169/internalmedicine.0925-18. PMID: 30449773Free PMC Article
Non-gastric Gastrointestinal Xanthomas: Case Series and Literature Review.
Díaz Del Arco C, Álvarez Sánchez Á, Fernández Aceñero MJ
J Gastrointestin Liver Dis 2016 Sep;25(3):389-94. PMID: 27689205
Esophagogastric pathology in morbid obese patient: Preoperative diagnosis, influence in the selection of surgical technique.
Estévez-Fernández S, Sánchez-Santos R, Mariño-Padín E, González-Fernández S, Turnes-Vázquez J
Rev Esp Enferm Dig 2015 Jul;107(7):408-12. PMID: 26140632

Clinical prediction guides

Relationship between gastric xanthoma, gastric precancerous lesions, and gastric cancer: A retrospective study.
Shen WN, Qu XD, Chen SS, Liu YH, Gao MJ, Shi YQ
J Dig Dis 2023 May;24(5):340-347. Epub 2023 Jul 28 doi: 10.1111/1751-2980.13202. PMID: 37417403
A Retroflexed View into the Metabolic Syndrome.
Hathorn KE, Najdawi F, Hamilton MJ
Gastroenterology 2020 Nov;159(5):e6-e7. Epub 2020 Apr 19 doi: 10.1053/j.gastro.2020.03.082. PMID: 32320691
Gastric Xanthoma Associated with Gastric Cancer Development: An Updated Review.
Moumin FA, Mohamed AA, Osman AA, Cai J
Can J Gastroenterol Hepatol 2020;2020:3578927. Epub 2020 Feb 21 doi: 10.1155/2020/3578927. PMID: 32149048Free PMC Article
Gastric Xanthoma Is a Predictive Marker for Early Gastric Cancer Detected after Helicobacter pylori Eradication.
Shibukawa N, Ouchi S, Wakamatsu S, Wakahara Y, Kaneko A
Intern Med 2019 Mar 15;58(6):779-784. Epub 2018 Nov 19 doi: 10.2169/internalmedicine.0925-18. PMID: 30449773Free PMC Article
Non-gastric Gastrointestinal Xanthomas: Case Series and Literature Review.
Díaz Del Arco C, Álvarez Sánchez Á, Fernández Aceñero MJ
J Gastrointestin Liver Dis 2016 Sep;25(3):389-94. PMID: 27689205

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