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Lung hilum neoplasm

MedGen UID:
224849
•Concept ID:
C1290358
•
Neoplastic Process
Synonyms: Hilar Lung Neoplasm; hilar lung neoplasm; Hilar Lung Tumor; hilar lung tumor; hilar lung tumour; Lung Hilum Neoplasm; lung hilum neoplasm; Lung Hilum Tumor; lung hilum tumor; lung hilum tumour; lung hilus neoplasm; lung hilus neoplasm (disease); lung hilus tumor; lung hilus tumour; Neoplasm of hilus of lung; neoplasm of hilus of lung; neoplasm of lung hilus; tumor of lung hilus; tumour of lung hilus
SNOMED CT: Neoplasm of hilus of lung (126707007)
 
Monarch Initiative: MONDO:0003639

Definition

A benign or malignant neoplasm that arises from the hilar region of the lung. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLung hilum neoplasm

Professional guidelines

PubMed

Salvage treatment of NSCLC recurrence after first-line chemotherapy failure: Iodine-125 seed brachytherapy or microwave ablation?
Liu B, Wang Y, Tian S, Hertzanu Y, Zhao X, Li Y
Thorac Cancer 2020 Mar;11(3):697-703. Epub 2020 Jan 29 doi: 10.1111/1759-7714.13320. PMID: 31995853Free PMC Article
The role of image-guided therapy in the management of colorectal cancer metastatic disease.
de Baere T, Tselikas L, Yevich S, Boige V, Deschamps F, Ducreux M, Goere D, Nguyen F, Malka D
Eur J Cancer 2017 Apr;75:231-242. Epub 2017 Feb 24 doi: 10.1016/j.ejca.2017.01.010. PMID: 28237869
Microwave ablation therapy: clinical utility in treatment of pulmonary metastases.
Vogl TJ, Naguib NN, Gruber-Rouh T, Koitka K, Lehnert T, Nour-Eldin NE
Radiology 2011 Nov;261(2):643-51. doi: 10.1148/radiol.11101643. PMID: 22012906

Recent clinical studies

Etiology

MSCT findings of primary Pulmonary mucoepidermoid carcinoma.
Liu Y, Liu M, Nie Y
Ann Med 2023;55(2):2263869. Epub 2023 Oct 2 doi: 10.1080/07853890.2023.2263869. PMID: 37783202Free PMC Article
Solitary Lung Nodule: CT-Guided Transthoracic Biopsy vs Transbronchial Biopsy With Endobronchial Ultrasound and Flexible Bronchoscope, a Meta-Analysis of Randomized Controlled Trials.
Ho ATN, Gorthi R, Lee R, Chawla M, Patolia S
Lung 2023 Feb;201(1):85-93. Epub 2023 Jan 25 doi: 10.1007/s00408-023-00596-9. PMID: 36695890
Primary pulmonary plasmacytoma: a case report introduction.
Nie S, Peng DC, Gong HH, Ye CL, Nie X, Li HJ
World J Surg Oncol 2016 Aug 4;14(1):205. doi: 10.1186/s12957-016-0948-8. PMID: 27487779Free PMC Article
Interventional chest radiology.
Tarver RD, Conces DJ Jr
Radiol Clin North Am 1994 Jul;32(4):689-709. PMID: 8022975
Selective mediastinoscopy.
Acosta JL, Manfredi F
Chest 1977 Feb;71(2):150-4. doi: 10.1378/chest.71.2.150. PMID: 832484

Diagnosis

Solitary Lung Nodule: CT-Guided Transthoracic Biopsy vs Transbronchial Biopsy With Endobronchial Ultrasound and Flexible Bronchoscope, a Meta-Analysis of Randomized Controlled Trials.
Ho ATN, Gorthi R, Lee R, Chawla M, Patolia S
Lung 2023 Feb;201(1):85-93. Epub 2023 Jan 25 doi: 10.1007/s00408-023-00596-9. PMID: 36695890
Primary pulmonary plasmacytoma: a case report introduction.
Nie S, Peng DC, Gong HH, Ye CL, Nie X, Li HJ
World J Surg Oncol 2016 Aug 4;14(1):205. doi: 10.1186/s12957-016-0948-8. PMID: 27487779Free PMC Article
Radiofrequency thermocoagulation of lung tumours. Where we are, where we are headed.
Gómez FM, Palussière J, Santos E, Tourdias T, Cornélis F, Sáiz V, Montes H, Eker O
Clin Transl Oncol 2009 Jan;11(1):28-34. doi: 10.1007/s12094-009-0307-0. PMID: 19155201
Mediastinoscopy, thoracoscopy, and video-assisted thoracic surgery in the diagnosis and staging of lung cancer.
Mentzer SJ
Hematol Oncol Clin North Am 1997 Jun;11(3):435-47. doi: 10.1016/s0889-8588(05)70442-1. PMID: 9209904
Interventional chest radiology.
Tarver RD, Conces DJ Jr
Radiol Clin North Am 1994 Jul;32(4):689-709. PMID: 8022975

Therapy

Stereotactic body radiation therapy for isolated hilar and mediastinal non-small cell lung cancers.
Horne ZD, Richman AH, Dohopolski MJ, Clump DA, Burton SA, Heron DE
Lung Cancer 2018 Jan;115:1-4. Epub 2017 Nov 10 doi: 10.1016/j.lungcan.2017.10.014. PMID: 29290248
The role of image-guided therapy in the management of colorectal cancer metastatic disease.
de Baere T, Tselikas L, Yevich S, Boige V, Deschamps F, Ducreux M, Goere D, Nguyen F, Malka D
Eur J Cancer 2017 Apr;75:231-242. Epub 2017 Feb 24 doi: 10.1016/j.ejca.2017.01.010. PMID: 28237869
Segmentectomy for c-T1N0M0 non-small cell lung cancer.
Nomori H
Surg Today 2014 May;44(5):812-9. Epub 2013 Jun 29 doi: 10.1007/s00595-013-0649-7. PMID: 23812915
Radiofrequency thermocoagulation of lung tumours. Where we are, where we are headed.
Gómez FM, Palussière J, Santos E, Tourdias T, Cornélis F, Sáiz V, Montes H, Eker O
Clin Transl Oncol 2009 Jan;11(1):28-34. doi: 10.1007/s12094-009-0307-0. PMID: 19155201
Interventional chest radiology.
Tarver RD, Conces DJ Jr
Radiol Clin North Am 1994 Jul;32(4):689-709. PMID: 8022975

Prognosis

Lobectomy versus segmentectomy: a propensity score-matched comparison of postoperative complications, pulmonary function and prognosis.
Nomori H, Yamazaki I, Machida Y, Otsuki A, Cong Y, Sugimura H, Oyama Y
Interact Cardiovasc Thorac Surg 2022 Jan 6;34(1):57-65. Epub 2021 Oct 25 doi: 10.1093/icvts/ivab212. PMID: 34999814Free PMC Article
Two-port intrapericardial left VATS pneumonectomy.
Nicotra S, Comacchio G, Natale G, Pangoni A, Rebusso A, Rea F
Multimed Man Cardiothorac Surg 2019 Dec 20;2019 doi: 10.1510/mmcts.2019.047. PMID: 31869011
Adenocarcinoma of the Rete Testis: Clinicopathologic and Immunohistochemical Characterization of 6 Cases and Review of the Literature.
Al-Obaidy KI, Idrees MT, Grignon DJ, Ulbright TM
Am J Surg Pathol 2019 May;43(5):670-681. doi: 10.1097/PAS.0000000000001219. PMID: 30676333
Primary pulmonary plasmacytoma: a case report introduction.
Nie S, Peng DC, Gong HH, Ye CL, Nie X, Li HJ
World J Surg Oncol 2016 Aug 4;14(1):205. doi: 10.1186/s12957-016-0948-8. PMID: 27487779Free PMC Article
Segmentectomy for c-T1N0M0 non-small cell lung cancer.
Nomori H
Surg Today 2014 May;44(5):812-9. Epub 2013 Jun 29 doi: 10.1007/s00595-013-0649-7. PMID: 23812915

Clinical prediction guides

Staplers versus energy devices for the intersegmental plane separation in thoracoscopic segmentectomy: a comparative study.
Han J, Yu H, Ma H
J Cardiothorac Surg 2022 Dec 17;17(1):319. doi: 10.1186/s13019-022-02070-8. PMID: 36528771Free PMC Article
Relationship between the Size and Location of the Mass and Hilar and Mediastinal Lymph Node Metastasis in Early and Locally Advanced Non-small Cell Lung Cancer.
Kuzucuoglu M, Gokyer A, Kula O, Yekdes AC, Sunal BS, Karamustafaoglu YA, Yoruk Y, Cicin I
J Coll Physicians Surg Pak 2020 Feb;30(2):172-176. doi: 10.29271/jcpsp.2020.02.172. PMID: 32036826
Adenocarcinoma of the Rete Testis: Clinicopathologic and Immunohistochemical Characterization of 6 Cases and Review of the Literature.
Al-Obaidy KI, Idrees MT, Grignon DJ, Ulbright TM
Am J Surg Pathol 2019 May;43(5):670-681. doi: 10.1097/PAS.0000000000001219. PMID: 30676333
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA): an overview and update for the cytopathologist.
VanderLaan PA, Wang HH, Majid A, Folch E
Cancer Cytopathol 2014 Aug;122(8):561-76. Epub 2014 Apr 23 doi: 10.1002/cncy.21431. PMID: 24760496
Port-access thoracoscopic anatomical lung subsegmentectomy.
Kato H, Oizumi H, Inoue T, Oba E, Nakamura K, Hayashi J, Watarai H, Yasumoto T, Sadahiro M
Interact Cardiovasc Thorac Surg 2013 Jun;16(6):824-9. Epub 2013 Feb 20 doi: 10.1093/icvts/ivt037. PMID: 23427315Free PMC Article

Recent systematic reviews

Development of the Korean Association for Lung Cancer Clinical Practice Guidelines: Recommendations on Radial Probe Endobronchial Ultrasound for Diagnosing Lung Cancer - An Updated Meta-Analysis.
Kim SH, Chung HS, Kim J, Kim MH, Lee MK, Kim I, Eom JS
Cancer Res Treat 2024 Apr;56(2):464-483. Epub 2023 Nov 29 doi: 10.4143/crt.2023.749. PMID: 38037321Free PMC Article
Ultrathin Bronchoscopy for the Diagnosis of Peripheral Pulmonary Lesions: A Meta-Analysis.
Kim SH, Kim J, Pak K, Eom JS
Respiration 2023;102(1):34-45. Epub 2022 Nov 22 doi: 10.1159/000527362. PMID: 36412624Free PMC Article
Computed Tomography Bronchus Sign and the Diagnostic Yield of Guided Bronchoscopy for Peripheral Pulmonary Lesions. A Systematic Review and Meta-Analysis.
Ali MS, Sethi J, Taneja A, Musani A, Maldonado F
Ann Am Thorac Soc 2018 Aug;15(8):978-987. doi: 10.1513/AnnalsATS.201711-856OC. PMID: 29877715

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