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Large cell carcinoma with rhabdoid phenotype

MedGen UID:
226828
•Concept ID:
C1265997
•
Neoplastic Process
Synonyms: Large Cell Carcinoma with Rhabdoid Phenotype; large cell carcinoma with rhabdoid phenotype; large cell carcinoma with rhabdoid phenotype (morphologic abnormality); Large Cell Lung Carcinoma with Rhabdoid Phenotype; large cell lung carcinoma with rhabdoid phenotype; Lung Large Cell Carcinoma with Rhabdoid Phenotype; RLCLC
SNOMED CT: Large cell carcinoma with rhabdoid phenotype (128629005)
 
Monarch Initiative: MONDO:0004237

Definition

A large cell lung carcinoma characterized by the presence of rhabdoid cells. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLarge cell carcinoma with rhabdoid phenotype

Professional guidelines

PubMed

SMARCA4-deficient Thoracic Sarcomas: Clinicopathologic Study of 30 Cases With an Emphasis on Their Nosology and Differential Diagnoses.
Perret R, Chalabreysse L, Watson S, Serre I, Garcia S, Forest F, Yvorel V, Pissaloux D, Thomas de Montpreville V, Masliah-Planchon J, Lantuejoul S, Brevet M, Blay JY, Coindre JM, Tirode F, Le Loarer F
Am J Surg Pathol 2019 Apr;43(4):455-465. doi: 10.1097/PAS.0000000000001188. PMID: 30451731

Recent clinical studies

Diagnosis

Large cell carcinoma of lung: On the verge of extinction?
Weissferdt A
Semin Diagn Pathol 2014 Jul;31(4):278-88. Epub 2014 Jun 12 doi: 10.1053/j.semdp.2014.06.005. PMID: 25023633
Pulmonary large cell carcinoma with rhabdoid phenotype.
Hiroshima K, Shibuya K, Shimamura F, Toyozaki T, Haga Y, Ohwada H, Iyoda A, Sekine Y, Iizasa T, Fujisawa T
Ultrastruct Pathol 2003 Jan-Feb;27(1):55-9. doi: 10.1080/01913120309949. PMID: 12554537

Prognosis

Pulmonary large cell carcinoma with rhabdoid phenotype.
Hiroshima K, Shibuya K, Shimamura F, Toyozaki T, Haga Y, Ohwada H, Iyoda A, Sekine Y, Iizasa T, Fujisawa T
Ultrastruct Pathol 2003 Jan-Feb;27(1):55-9. doi: 10.1080/01913120309949. PMID: 12554537

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