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Lipomatous hamartoma

MedGen UID:
227000
•Concept ID:
C1302836
•
Disease or Syndrome
Synonym: Lipomatous Hamartoma
SNOMED CT: Lipomatous hamartoma (400111008); Lipomatous hamartoma (788527002)

Definition

A benign hamartomatous lesion composed predominantly of adipose tissue. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLipomatous hamartoma

Professional guidelines

PubMed

Syndromes with focal overgrowth in infancy: diagnostic approach and surgical treatment.
Mirastschijski U, Altmann S, Lenz-Scharf O, Muschke P, Schneider W
J Plast Surg Hand Surg 2012 Feb;46(1):45-8. Epub 2010 Sep 6 doi: 10.3109/02844310902957728. PMID: 21446802

Recent clinical studies

Etiology

Pancreatic Lipomatous Hamartoma: A Hitherto Unrecognized Variant.
Tanaka M, Ushiku T, Ikemura M, Takazawa Y, Igari T, Shimizu M, Yamaguchi H, Fukushima N, Sakuma K, Arita J, Sakamoto Y, Hasegawa K, Watadani T, Nakai Y, Koike K, Fukayama M
Am J Surg Pathol 2018 Jul;42(7):891-897. doi: 10.1097/PAS.0000000000001075. PMID: 29738363
Endobronchial lipomatous hamartoma with mediastinal extension.
Tsitouridis I, Michaelides M, Kyriakou V, Arvanity M
J Thorac Imaging 2010 Feb;25(1):W6-9. doi: 10.1097/RTI.0b013e318199fbd5. PMID: 20160589

Diagnosis

Pancreatic hamartoma: detection of harbouring NAB2::STAT6 fusion gene.
Tanigawa M, Koga Y, Naito Y, Yamaguchi H, Iwasaki T, Kohashi K, Ohike N, Hanada K, Higashi M, Komatsu M, Imai H, Yamakita K, Nagakawa T, Okabe Y, Kato S, Noguchi H, Nakayama T, Yasuda M, Kusano H, Akiba J, Oda Y, Yano H
Histopathology 2022 Sep;81(3):319-328. Epub 2022 Jul 14 doi: 10.1111/his.14703. PMID: 35758200
Rare case of pancreatic lipomatous hamartoma.
Tee CL, Lin EY, Bundele MM, Low JK
BMJ Case Rep 2022 Apr 7;15(4) doi: 10.1136/bcr-2021-248132. PMID: 35393275Free PMC Article
Encephalocraniocutaneous Lipomatosis: Haberland Syndrome.
Özdoğan S, Saymaz C, Yaltırık CK, Düzkalır HG, Kaya M, Demirel N, Düzkalır AH, Sarıkaya B, Aktekin B
Am J Case Rep 2017 Dec 1;18:1271-1275. doi: 10.12659/ajcr.907685. PMID: 29192135Free PMC Article
Primary valvular lipomatous hamartoma: a case report and a collective review of the literature.
Karasu BB, Yeter E, Yilmazer D, Kiziltepe U, Ulular O, Akdemir R
Cardiovasc Pathol 2011 Nov-Dec;20(6):377-80. Epub 2010 Oct 30 doi: 10.1016/j.carpath.2010.09.005. PMID: 21036628
Encephalocraniocutaneous lipomatosis.
Gawel J, Schwartz RA, Józwiak S
J Cutan Med Surg 2003 Jan-Feb;7(1):61-5. Epub 2002 Oct 9 doi: 10.1007/s10227-002-1142-x. PMID: 12362260

Prognosis

Rare case of pancreatic lipomatous hamartoma.
Tee CL, Lin EY, Bundele MM, Low JK
BMJ Case Rep 2022 Apr 7;15(4) doi: 10.1136/bcr-2021-248132. PMID: 35393275Free PMC Article
Endobronchial lipomatous hamartoma with mediastinal extension.
Tsitouridis I, Michaelides M, Kyriakou V, Arvanity M
J Thorac Imaging 2010 Feb;25(1):W6-9. doi: 10.1097/RTI.0b013e318199fbd5. PMID: 20160589
Encephalocraniocutaneous lipomatosis.
Gawel J, Schwartz RA, Józwiak S
J Cutan Med Surg 2003 Jan-Feb;7(1):61-5. Epub 2002 Oct 9 doi: 10.1007/s10227-002-1142-x. PMID: 12362260

Clinical prediction guides

Pancreatic hamartoma: detection of harbouring NAB2::STAT6 fusion gene.
Tanigawa M, Koga Y, Naito Y, Yamaguchi H, Iwasaki T, Kohashi K, Ohike N, Hanada K, Higashi M, Komatsu M, Imai H, Yamakita K, Nagakawa T, Okabe Y, Kato S, Noguchi H, Nakayama T, Yasuda M, Kusano H, Akiba J, Oda Y, Yano H
Histopathology 2022 Sep;81(3):319-328. Epub 2022 Jul 14 doi: 10.1111/his.14703. PMID: 35758200
Mammary cystosarcoma with mature adipose stromal differentiation (lipophyllodes tumor) arising in a lipomatous hamartoma.
Rosen PP, Romain K, Liberman L
Arch Pathol Lab Med 1994 Jan;118(1):91-4. PMID: 8285842

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